GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgA	Patient 1	10	moderate	G00057MO	450
IgA	Patient 1	22	moderate	G00057MO	477
IgA	Patient 1	6	moderate	G00057MO	365
IgG	Patient 1	10	moderate	G00057MO	54
IgG	Patient 1	22	moderate	G00057MO	79
IgG	Patient 1	6	moderate	G00057MO	58
IgM	Patient 1	10	moderate	G00057MO	276
IgM	Patient 1	22	moderate	G00057MO	543
IgA	Patient 2	15	mild	G00057MO	677
IgA	Patient 2	24	mild	G00057MO	879
IgG	Patient 2	15	mild	G00057MO	115
IgG	Patient 2	24	mild	G00057MO	155
IgM	Patient 2	15	mild	G00057MO	943
IgM	Patient 2	24	mild	G00057MO	1330
IgM	Patient 1	6	moderate	G00057MO	325
IgA	Patient 2	3	mild	G00057MO	817
IgG	Patient 2	3	mild	G00057MO	143
IgM	Patient 2	3	mild	G00057MO	1155
IgA	Patient 3	-180	mild	G00057MO	390
IgA	Patient 3	11	mild	G00057MO	818
IgG	Patient 3	-180	mild	G00057MO	84
IgG	Patient 3	11	mild	G00057MO	215
IgM	Patient 3	-180	mild	G00057MO	442
IgA	Patient 3	4	mild	G00057MO	945
IgG	Patient 3	4	mild	G00057MO	216