GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgG	Patient 2	24	mild	G36544AC	256
IgM	Patient 2	15	mild	G36544AC	665
IgM	Patient 2	24	mild	G36544AC	935
IgG	Patient 1	6	moderate	G36544AC	32
IgM	Patient 1	6	moderate	G36544AC	95
IgA	Patient 2	3	mild	G36544AC	1007
IgG	Patient 2	3	mild	G36544AC	258
IgM	Patient 2	3	mild	G36544AC	623
IgA	Patient 3	-180	mild	G36544AC	267
IgA	Patient 3	11	mild	G36544AC	457
IgG	Patient 3	-180	mild	G36544AC	47
IgM	Patient 3	-180	mild	G36544AC	89
IgA	Patient 3	4	mild	G36544AC	494
IgG	Patient 3	11	mild	G36544AC	54
IgG	Patient 3	4	mild	G36544AC	54
IgM	Patient 3	11	mild	G36544AC	198
IgM	Patient 3	4	mild	G36544AC	185
IgA	Patient 4	12	mild	G36544AC	486
IgG	Patient 4	12	mild	G36544AC	95
IgM	Patient 4	12	mild	G36544AC	311
IgA	Patient 1	10	moderate	G37036SF	432
IgA	Patient 1	22	moderate	G37036SF	346
IgA	Patient 1	6	moderate	G37036SF	403
IgG	Patient 1	10	moderate	G37036SF	22
IgG	Patient 1	22	moderate	G37036SF	24