GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▼	Arbitrary Fluorescence Units (AFU)
IgA	Patient 2	3	mild	G47566FL	420
IgG	Patient 2	3	mild	G47566FL	8386
IgM	Patient 2	3	mild	G47566FL	165
IgA	Patient 3	-180	mild	G47566FL	254
IgA	Patient 3	11	mild	G47566FL	451
IgG	Patient 3	-180	mild	G47566FL	46
IgM	Patient 3	-180	mild	G47566FL	61
IgA	Patient 3	4	mild	G47566FL	500
IgG	Patient 3	11	mild	G47566FL	64
IgG	Patient 3	4	mild	G47566FL	65
IgM	Patient 3	11	mild	G47566FL	79
IgM	Patient 3	4	mild	G47566FL	68
IgA	Patient 4	12	mild	G47566FL	398
IgG	Patient 4	12	mild	G47566FL	94
IgM	Patient 4	12	mild	G47566FL	244
IgA	Patient 1	10	moderate	G47548GA	321
IgA	Patient 1	22	moderate	G47548GA	304
IgA	Patient 1	6	moderate	G47548GA	320
IgG	Patient 1	10	moderate	G47548GA	22
IgG	Patient 1	22	moderate	G47548GA	22
IgM	Patient 1	10	moderate	G47548GA	31
IgM	Patient 1	22	moderate	G47548GA	34
IgA	Patient 2	15	mild	G47548GA	416
IgA	Patient 2	24	mild	G47548GA	464
IgG	Patient 2	15	mild	G47548GA	80