GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgA	Patient 1	10	moderate	G41200QS	373
IgA	Patient 1	22	moderate	G41200QS	403
IgA	Patient 1	6	moderate	G41200QS	359
IgG	Patient 1	10	moderate	G41200QS	25
IgG	Patient 1	22	moderate	G41200QS	37
IgM	Patient 1	10	moderate	G41200QS	50
IgM	Patient 1	22	moderate	G41200QS	187
IgA	Patient 2	15	mild	G41200QS	378
IgA	Patient 2	24	mild	G41200QS	384
IgG	Patient 2	15	mild	G41200QS	1253
IgG	Patient 2	24	mild	G41200QS	1135
IgM	Patient 2	15	mild	G41200QS	71
IgM	Patient 2	24	mild	G41200QS	62
IgG	Patient 1	6	moderate	G41200QS	27
IgM	Patient 1	6	moderate	G41200QS	58
IgA	Patient 2	3	mild	G41200QS	374
IgG	Patient 2	3	mild	G41200QS	1878
IgM	Patient 2	3	mild	G41200QS	75
IgA	Patient 3	-180	mild	G41200QS	255
IgA	Patient 3	11	mild	G41200QS	424
IgG	Patient 3	-180	mild	G41200QS	38
IgM	Patient 3	-180	mild	G41200QS	57
IgA	Patient 3	4	mild	G41200QS	427
IgG	Patient 3	11	mild	G41200QS	186
IgG	Patient 3	4	mild	G41200QS	162