GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgM	Patient 1	10	moderate	G43648DB	32
IgM	Patient 1	22	moderate	G43648DB	53
IgA	Patient 2	15	mild	G43648DB	506
IgA	Patient 2	24	mild	G43648DB	593
IgG	Patient 2	15	mild	G43648DB	85
IgG	Patient 2	24	mild	G43648DB	90
IgM	Patient 2	15	mild	G43648DB	703
IgM	Patient 2	24	mild	G43648DB	791
IgG	Patient 1	6	moderate	G43648DB	25
IgM	Patient 1	6	moderate	G43648DB	27
IgA	Patient 2	3	mild	G43648DB	329
IgG	Patient 2	3	mild	G43648DB	41
IgM	Patient 2	3	mild	G43648DB	131
IgA	Patient 3	-180	mild	G43648DB	1049
IgA	Patient 3	11	mild	G43648DB	2073
IgG	Patient 3	-180	mild	G43648DB	326
IgM	Patient 3	-180	mild	G43648DB	2796
IgA	Patient 3	4	mild	G43648DB	1827
IgG	Patient 3	11	mild	G43648DB	652
IgG	Patient 3	4	mild	G43648DB	575
IgM	Patient 3	11	mild	G43648DB	6334
IgM	Patient 3	4	mild	G43648DB	5607
IgA	Patient 4	12	mild	G43648DB	406
IgG	Patient 4	12	mild	G43648DB	214
IgM	Patient 4	12	mild	G43648DB	158