GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgM	Patient 3	11	mild	G47362BJ	1619
IgM	Patient 3	4	mild	G47362BJ	1637
IgA	Patient 4	12	mild	G47362BJ	790
IgG	Patient 4	12	mild	G47362BJ	190
IgM	Patient 4	12	mild	G47362BJ	1337
IgA	Patient 1	10	moderate	G47548GA	321
IgA	Patient 1	22	moderate	G47548GA	304
IgA	Patient 1	6	moderate	G47548GA	320
IgG	Patient 1	10	moderate	G47548GA	22
IgG	Patient 1	22	moderate	G47548GA	22
IgM	Patient 1	10	moderate	G47548GA	31
IgM	Patient 1	22	moderate	G47548GA	34
IgA	Patient 2	15	mild	G47548GA	416
IgA	Patient 2	24	mild	G47548GA	464
IgG	Patient 2	15	mild	G47548GA	80
IgG	Patient 2	24	mild	G47548GA	83
IgM	Patient 2	15	mild	G47548GA	428
IgM	Patient 2	24	mild	G47548GA	470
IgG	Patient 1	6	moderate	G47548GA	24
IgM	Patient 1	6	moderate	G47548GA	29
IgA	Patient 2	3	mild	G47548GA	480
IgG	Patient 2	3	mild	G47548GA	94
IgM	Patient 2	3	mild	G47548GA	516
IgA	Patient 3	-180	mild	G47548GA	298
IgA	Patient 3	11	mild	G47548GA	397