GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgG	Patient 3	-180	mild	G57449OF	44
IgM	Patient 3	-180	mild	G57449OF	71
IgA	Patient 3	4	mild	G57449OF	489
IgG	Patient 3	11	mild	G57449OF	197
IgG	Patient 3	4	mild	G57449OF	208
IgM	Patient 3	11	mild	G57449OF	89
IgM	Patient 3	4	mild	G57449OF	95
IgA	Patient 4	12	mild	G57449OF	352
IgG	Patient 4	12	mild	G57449OF	41
IgM	Patient 4	12	mild	G57449OF	79
IgA	Patient 1	10	moderate	G58547FH	340
IgA	Patient 1	22	moderate	G58547FH	349
IgA	Patient 1	6	moderate	G58547FH	311
IgG	Patient 1	10	moderate	G58547FH	22
IgG	Patient 1	22	moderate	G58547FH	27
IgM	Patient 1	10	moderate	G58547FH	39
IgM	Patient 1	22	moderate	G58547FH	91
IgA	Patient 2	15	mild	G58547FH	425
IgA	Patient 2	24	mild	G58547FH	494
IgG	Patient 2	15	mild	G58547FH	41
IgG	Patient 2	24	mild	G58547FH	40
IgM	Patient 2	15	mild	G58547FH	225
IgM	Patient 2	24	mild	G58547FH	256
IgG	Patient 1	6	moderate	G58547FH	22
IgM	Patient 1	6	moderate	G58547FH	33