Agglutinin alpha chain

Summary
Lectin Name Aliases
  • Artocarpus Integrifolia Agglutinin
  • Jacalin
  • jacalin
Monosaccharide Specificities
  • Gal
Organism
Artocarpus integer
UniProt
P18670
LfDB
UniLectin
P18670
CarboGrove
Annotation
Keyword
  • 3D-structure
  • Direct protein sequencing
  • Glycoprotein
  • IgA-binding protein
  • Lectin
  • Repeat
Gene Ontology (GO)
Displaying all 2 entries
GO Term
IgA binding
carbohydrate binding
Reference
Displaying entries 11 - 20 of 22 in total
PubMed ID Title First Author
15342645 An inhibitor of O-glycosylation induces apoptosis in NIH3T3 cells and developing mouse embryonic mandibular tissues. Tian E
15329359 A database analysis of jacalin-like lectins: sequence-structure-function relationships. Raval S
15944373 Crystal structure of banana lectin reveals a novel second sugar binding site. Meagher JL
16177266 Elucidation of binding specificity of Jacalin toward O-glycosylated peptides: quantitative analysis by frontal affinity chromatography. Tachibana K
17210577 Maize beta-glucosidase-aggregating factor is a polyspecific jacalin-related chimeric lectin, and its lectin domain is responsible for beta-glucosidase aggregation. Kittur FS
19056785 Homolog of the maize beta-glucosidase aggregating factor from sorghum is a jacalin-related GalNAc-specific lectin but lacks protein aggregating activity. Kittur FS
20080975 A lectin isolated from bananas is a potent inhibitor of HIV replication. Swanson MD
21846723 Hemolysin induces Toll-like receptor (TLR)-independent apoptosis and multiple TLR-associated parallel activation of macrophages. Chakraborty DC
21948871 ZG16p, an animal homolog of β-prism fold plant lectins, interacts with heparan sulfate proteoglycans in pancreatic zymogen granules. Kumazawa-Inoue K
21964726 Jacalin interaction with human immunoglobulin A1 and bovine immunoglobulin G1: affinity constant determined by piezoelectric biosensoring. Pedroso MM
Lectin Frontier DataBase (LfDB)
GlyTouCan
G19083SI
V-V0
50.79
GlyTouCan
G62167DK
V-V0
45.44
GlyTouCan
G83131MU
V-V0
44.29
UniLectin
UniProt
P18670
CarboGrove
Lectin Name
Artocarpus Integrifolia Agglutinin
Common Name
Jacalin
Automated Analysis report (Top 10 high affinity glycans)
Array Source
CFG
Protein Source
Vector
Concentration (ug/mL)

GlyTouCan ID Binding Intensity Stdev
G00035MO
973.09 32.23
G32723SL
924.53 41.17
G26166QH
792.53 66.23
G76607YV
543.61 17.8
G76355TG
455.82 37.17
G75472OU
419.92 8.11
G57321FI
401.46 4.71
G00031MO
401.02 137.07
G00035MO
390.14 27.47
G97763JB
373.47 9.76

GlyTouCan ID Binding Intensity Stdev
G65562ZE
40277.82 2014.56
G26166QH
36580.89 323.38
G75472OU
36553.51 1080.19
G00031MO
36337.1 632.92
G77477NL
35996.59 2583.39
G65562ZE
34227.09 2033.91
G76355TG
33974.96 1196.27
G32723SL
33173.54 350.21
G00035MO
32958.7 809.62
G00035MO
31373.91 1486.2

GlyTouCan ID Binding Intensity Stdev
G01801SZ
47815.46 13655.63
G75472OU
46194.58 1124.96
G23438NR
45443.4 12680.72
G97763JB
38540.01 1602.28
G32723SL
38301.36 1321.12
G00035MO
37557 845.17
G77477NL
36997.99 11075.92
G57321FI
36866.7 849.31
G51162XR
36117.79 2526.28
G65562ZE
36107.49 511.44

GlyTouCan ID Binding Intensity Stdev
G75472OU
46978.21 2173.63
G77477NL
41438.68 6869.46
G73991ZU
41165.36 10079.52
G92115PW
41162.64 5422.24
G23438NR
40406.36 12010.57
G11647UD
39533.42 6805.28
G01801SZ
39456.16 5100.01
G32723SL
39067.42 2426.95
G97763JB
38683.35 945.39
G65562ZE
38377.72 1290.4
Array Source
ZBiotech
Protein Source
Vector
Concentration (ug/mL)

GlyTouCan ID Binding Intensity Stdev
G57321FI
31915.83 0
G00031MO
31062.17 0
G88313DY
29717 0
G99315PE
29614.33 0
G94435QH
28848.5 0
G47548GA
27742.33 0
G00035MO
27723 0
G00068MO
27001.17 0
G83950JR
26724 0
G83120FP
25512 0

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025