GlyCosmos Portal

Submissions

Lectin/endochitinase 1

Summary

Lectin Name Aliases

UDA
Urtica Dioica Agglutinin

Monosaccharide Specificities

GlcNAc

Organism

Urtica dioica (great nettle)

External Links

UniProt

P11218

LfDB

LfDB0168

UniLectin

P11218

CarboGrove

1267

Annotation

Keyword

3D-structure
Chitin degradation
Chitin-binding
Direct protein sequencing
Disulfide bond
Fungicide
Glycoprotein
Glycosidase
Lectin
Metal-binding
Plant defense
Pyrrolidone carboxylic acid
Repeat
Signal
Zinc

Gene Ontology (GO)

Displaying **all 5** entries
GO Term
cell wall macromolecule catabolic process
chitin catabolic process
polysaccharide catabolic process
killing of cells of another organism
defense response to fungus

Displaying **all 4** entries
GO Term
chitinase activity
chitin binding
carbohydrate binding
metal ion binding

Annotation information from UniProt.

Reference

Displaying **all 3** entries
PubMed ID	Title	First Author
1375935	The gene for stinging nettle lectin (Urtica dioica agglutinin) encodes both a lectin and a chitinase.	Lerner DR
16183648	Carbohydrate-binding agents cause deletions of highly conserved glycosylation sites in HIV GP120: a new therapeutic concept to hit the achilles heel of HIV.	Balzarini J
20507987	Microvirin, a novel alpha(1,2)-mannose-specific lectin isolated from Microcystis aeruginosa, has anti-HIV-1 activity comparable with that of cyanovirin-N but a much higher safety profile.	Huskens D

Lectin Frontier DataBase (LfDB)

GlyTouCan: G87825QP
V-V₀: 1586.8

GlyTouCan: G66257KQ
V-V₀: 1528.8

GlyTouCan: G70358QM
V-V₀: 1117.5

LfDB provides quantitative interaction data in terms of the affinity constants (K_a) of a series of lectins toward a panel of pyridylaminated (PA) glycans obtained by an automated frontal affinity chromatography with fluorescence detection (FAC-FD) system. Since the data are accurate and reliable, providing the absolute values of sugar-protein interactions, LfDB would be a valuable resource in the studies of glycan-related biology.

UniLectin

UniProt
P11218

CarboGrove

Lectin Name: Urtica Dioica Agglutinin
Common Name: UDA

Automated Analysis report (Top 10 high affinity glycans)

Array Source

CFG

Protein Source

EY Labs

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G80966KZ	7872.13	835.03
G40702WU	6953.03	502.92
G55220VL	5825.69	29.09
G60230HH	4297.95	160.79
G63337SS	3973.45	376.49
G22768VO	2517.56	123.97
G22768VO	1498.51	96.5
G62112AO	1046.08	155.05
G69411IG	970.97	26.56
G82348BZ	686.15	45.31

GlyTouCan ID	Binding Intensity	Stdev
G80966KZ	16804.2	1588.98
G40702WU	15723.9	446.16
G22768VO	14550.48	1900.44
G55220VL	11983.52	420.53
G63337SS	10603.81	783.67
G69411IG	6789.62	427.03
G22768VO	6455.43	448.75
G60230HH	6006.31	180.6
G62112AO	5433.84	130.92
G82348BZ	2387.7	226.1

GlyTouCan ID	Binding Intensity	Stdev
G22768VO	20542.8	3309.91
G80966KZ	18082.13	416.89
G40702WU	17600.84	290.94
G55220VL	16714.8	441.63
G22768VO	11622.98	1318.44
G69411IG	11587.77	936.83
G63337SS	11056.35	1761.66
G62112AO	10058.57	771.86
G60230HH	7717.79	293.05
G07670VS	5884.95	560.21

GlyTouCan ID	Binding Intensity	Stdev
G80966KZ	25159.88	1105.75
G22768VO	23450.37	885.14
G00720XU	21706.03	2004.26
G55220VL	21030.2	348.35
G69411IG	20317.37	1439.5
G40702WU	19391.7	780.29
G47362BJ	19370.44	1245.34
G70021TR	18944.13	520.84
G62112AO	18696.13	1914.07
G22768VO	18325.43	1711.14

CarboGrove View

CarboGrove is populated with the results from 35 types of glycan arrays, 13 glycan families, 5 experimental methods, and 19 laboratories or companies by processing and interpreting data from various types of glycan arrays.

PDB

1EN2

1ENM

1IQB

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

Lectin Frontier DataBase (LfDB)

CarboGrove

PDB

International Collaboration

Acknowledgements

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

Lectin Frontier DataBase (LfDB)

CarboGrove

0.1

1

10

100

PDB

International Collaboration

Acknowledgements