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MIRAGE
Agglutinin

Summary
Lectin Name Aliases
  • HPA
  • Helix Pomatia Agglutinin
Organism
Helix pomatia (Roman snail)
UniProt
Q2F1K8
LfDB
UniLectin
Q2F1K8
CarboGrove
Annotation
Keyword
  • 3D-structure
  • Metal-binding
  • Signal
  • Zinc
Gene Ontology (GO)
Displaying 1 entry
GO Term
cell-cell adhesion
Annotation information from UniProt.
Reference
Displaying all 5 entries
PubMed ID Title First Author
8724140 Forssman disaccharide is the specific ligand of a galectin from the sponge Geodia cydonium but does not mediate its binding to nuclear protein np56. Hanisch FG
16704980 Biochemical and structural analysis of Helix pomatia agglutinin. A hexameric lectin with a novel fold. Sanchez JF
17652409 Structural basis for recognition of breast and colon cancer epitopes Tn antigen and Forssman disaccharide by Helix pomatia lectin. Lescar J
21372134 Identification, cloning, and characterization of two N-acetylgalactosamine-binding lectins from the albumen gland of Helix pomatia. Markiv A
22322011 The lectin Helix pomatia agglutinin recognizes O-GlcNAc containing glycoproteins in human breast cancer. Rambaruth ND
Lectin Frontier DataBase (LfDB)
GlyTouCan
G51497IR
V-V0
175.8
GlyTouCan
G37918PT
V-V0
35.64
GlyTouCan
G08453FV
V-V0
32.49
LfDB provides quantitative interaction data in terms of the affinity constants (Ka) of a series of lectins toward a panel of pyridylaminated (PA) glycans obtained by an automated frontal affinity chromatography with fluorescence detection (FAC-FD) system. Since the data are accurate and reliable, providing the absolute values of sugar-protein interactions, LfDB would be a valuable resource in the studies of glycan-related biology.
MCAW
The MCAW profile of the top three glycans above, which resulted from FAC analysis.
UniLectin
UniProt
Q2F1K8
CarboGrove
Lectin Name
Helix Pomatia Agglutinin
Common Name
HPA
Automated Analysis report (Top 10 high affinity glycans)
Array Source
CFG
Protein Source
EY Labs
Concentration (ug/mL)

GlyTouCan ID Binding Intensity Stdev
G19687OL
211.03 130.5
G11960UF
149.2 10.77
G06714AG
114.73 15.16
G35382VN
103.86 8.94
G18988VX
99.09 12.62
G09520ZQ
91.76 15.65
G64586PM
88.1 13.49
G71121NN
87.77 19.29
G95492XR
87.23 58.42
G02522JF
83.51 11.93

GlyTouCan ID Binding Intensity Stdev
G19687OL
247.33 31.69
G80062GG
184.59 62.6
G11960UF
159.59 34.61
G80966KZ
110.53 9.09
G35382VN
95.19 24.32
G18988VX
75.35 21.72
G80313NY
71.67 5.53
G00031MO
67.6 45.22
G06714AG
54.14 23.69
G85213RR
52.89 93.28

GlyTouCan ID Binding Intensity Stdev
G80062GG
2876.72 1443.24
G80313NY
536.31 22.68
G08157XK
492.74 81.27
G97834OQ
346.6 89.85
G35382VN
342.69 30.98
G19687OL
293.04 184.8
G00031MO
280.97 9.05
G40696TO
279.21 60.59
G40696TO
215.16 32.85
G42463OP
211.83 20.16

GlyTouCan ID Binding Intensity Stdev
G80062GG
35009.99 1366.54
G00031MO
31710.86 2511.88
G00035MO
31566.08 1123.39
G26166QH
31356.2 1711.24
G97834OQ
30674.26 704.71
G92743LI
28814.82 650.35
G75472OU
24585.17 1637.18
G08157XK
20775.65 516.34
G60233WN
18875 1841.73
G80313NY
16140.52 762.78
CarboGrove View
Array Source
CFG
Protein Source
Sigma
Concentration (ug/mL)

GlyTouCan ID Binding Intensity Stdev
G88356HA
4328.52 657.92
G36698XD
4156.59 586.6
G54826OZ
4069.69 170.2
G08157XK
3909.83 235.45
G87385MI
3904.23 171.38
G40025AL
3800.97 281.13
G04187IN
3361.42 272.38
G26298FT
3192.21 489.76
G66163TI
2985.43 307.56
G66367EU
2866.78 192.49

GlyTouCan ID Binding Intensity Stdev
G26298FT
21969.07 2453.9
G36698XD
20840.07 2270.15
G88356HA
20037.13 308.38
G40025AL
19362.26 1477.05
G44060QH
19088.44 1992.07
G04187IN
19018.47 423.47
G08157XK
18307.26 337.14
G87385MI
18121.17 1315.35
G80062GG
17065.9 863.51
G54826OZ
15575.54 866.6

GlyTouCan ID Binding Intensity Stdev
G36698XD
34579.14 1931.88
G26298FT
31081.93 1512.06
G92743LI
28553.26 1501.78
G00066MO
27607.07 1007.93
G60233WN
27335.64 632.16
G40025AL
26618.71 2414.21
G88356HA
26288.21 2569.65
G04187IN
26230.26 1973.23
G97834OQ
25750.44 850.24
G44060QH
25725.46 2343.46

GlyTouCan ID Binding Intensity Stdev
G97834OQ
39634.01 1308.17
G00066MO
37398.41 1841.19
G66916RU
29407.99 3680.12
G60233WN
28506.02 1277.85
G92743LI
28026.85 616.11
G74353FF
27937.43 2060.71
G26298FT
26480.71 231.46
G57321FI
25857.14 1280.54
G36698XD
25273.67 883.02
G00066MO
24603.06 805.79
CarboGrove View
Array Source
NCFG
Protein Source
Sigma
Concentration (ug/mL)

GlyTouCan ID Binding Intensity Stdev
G27432KC
61241 3725
G26298FT
60994 2845
G79809MM
57353 4310
G19524AS
55193 4038
G04187IN
54726 2340
G40025AL
52471 1687
G87385MI
51296 5422
G44060QH
50230 3197
G88356HA
49583 692
G70021TR
47714 2828

GlyTouCan ID Binding Intensity Stdev
G31152NK
61931 2415
G26298FT
60758 3096
G19524AS
60166 2203
G79809MM
57434 4660
G00066MO
56978 2573
G74353FF
56090 1647
G57321FI
54653 598
G44060QH
54079 2455
G70021TR
53646 6095
G27432KC
52756 4414
CarboGrove View
Array Source
NGGM
Protein Source
Sigma
Concentration (ug/mL)

GlyTouCan ID Binding Intensity Stdev
G96428WC
11900 0
G48061MK
8493 0
G88356HA
2334 0
G61026ND
1542 0
G11928TH
1345 0
G33888AF
1258 0
G77620XT
1135 0
G88766TD
1122 0
G06031DD
995 0
G48600JD
632 0
CarboGrove View
Array Source
NGGM-TM
Protein Source
Sigma
Concentration (ug/mL)

GlyTouCan ID Binding Intensity Stdev
G06031DD
65395.75 156.58
G77620XT
65186.75 297.91
G11928TH
64928.75 344.12
G88766TD
64631.75 668.44
G48061MK
64523.25 174.93
G61026ND
64405.5 1180.78
G48600JD
64350.5 1009.38
G96428WC
64096.25 330.85
G33888AF
63949.75 914.73
G88356HA
63551 322.79
CarboGrove View
Array Source
ZBiotech
Protein Source
Sigma
Concentration (ug/mL)

GlyTouCan ID Binding Intensity Stdev
G57321FI
16116.33 0
G17480GI
10087.66 0
G19524AS
8643.83 0
G66163TI
7963.83 0
G57321FI
7709.66 0
G99315PE
7190.5 0
G00066MO
4709 0
G74353FF
4699.33 0
G02710ET
3278.5 0
G00031MO
552.83 0
CarboGrove View
CarboGrove is populated with the results from 35 types of glycan arrays, 13 glycan families, 5 experimental methods, and 19 laboratories or companies by processing and interpreting data from various types of glycan arrays.
MCAW-DB (Glycan Recognition Profile)
MCAW-DB is a database whereby users can view the multiple alignment analysis results obtained from the MCAW tool, which can computationally find common glycan substructures among a group of glycan structures. The data in MCAW-DB are analysis results of glycan array experiments; those glycans having higher binding affinity to glycan binding proteins (GBPs) have been analyzed and can be viewed as “glycan recognition profiles”. Currently, this database provides published analysis results of glycan array data from the Consortium for Functional Glycomics (CFG).
PDB
2CCV
© PDBj クリエイティブ・コモンズ 表示 4.0 国際 ライセンス
2CE6
© PDBj クリエイティブ・コモンズ 表示 4.0 国際 ライセンス
2CGY
© PDBj クリエイティブ・コモンズ 表示 4.0 国際 ライセンス
2CGZ
© PDBj クリエイティブ・コモンズ 表示 4.0 国際 ライセンス
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025