GlyCosmos Portal

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Sialic acid-binding Ig-like lectin 12

Summary

Lectin Name Aliases

Mouse Siglec-E
Siglec-E

Organism

Mus musculus (house mouse)

External Links

UniProt

Q91Y57

CarboGrove

1115

Annotation

Keyword

Cell adhesion
Disulfide bond
Glycoprotein
Immunoglobulin domain
Lectin
Phosphoprotein
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 5** entries
GO Term
inflammatory response
cell adhesion
negative regulation of inflammatory response
phagocytosis, engulfment
negative regulation of phagocytosis, engulfment

Displaying **all 2** entries
GO Term
external side of plasma membrane
membrane

Displaying **all 2** entries
GO Term
monosaccharide binding
sialic acid binding

Annotation information from UniProt.

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Mus musculus
Neutrophil degranulation	Mus musculus

CarboGrove

Lectin Name: Mouse Siglec-E
Common Name: Siglec-E

Automated Analysis report (Top 10 high affinity glycans)

Array Source

CFG

Protein Source

Investigator Provided

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G76571JT	1561.89	448.77
G19134QI	540.39	192.57
G90672BM	530.63	172.74
G91237TK	504.42	79.64
G78008YE	468.72	349.47
G49542DJ	448.98	203.49
G65562ZE	426.75	119.46
G09546QO	384.8	65
G91257NC	366.69	109.1
G90562PB	353.15	20.77

CarboGrove View

CarboGrove is populated with the results from 35 types of glycan arrays, 13 glycan families, 5 experimental methods, and 19 laboratories or companies by processing and interpreting data from various types of glycan arrays.

MCAW-DB (Glycan Recognition Profile)

5403

MCAW-DB is a database whereby users can view the multiple alignment analysis results obtained from the MCAW tool, which can computationally find common glycan substructures among a group of glycan structures. The data in MCAW-DB are analysis results of glycan array experiments; those glycans having higher binding affinity to glycan binding proteins (GBPs) have been analyzed and can be viewed as “glycan recognition profiles”. Currently, this database provides published analysis results of glycan array data from the Consortium for Functional Glycomics (CFG).

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