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Seed lectin subunit I

Summary

Lectin Name Aliases

DBA
DBL
Dolichos Biflorus Agglutinin

Monosaccharide Specificities

Gal
GalNAc

Organism

Vigna cylindrica

External Links

UniProt

P05045

LfDB

LfDB0174

UniLectin

P05045

CarboGrove

Annotation

Keyword

3D-structure
Calcium
Glycoprotein
Mannose-binding
Signal

Gene Ontology (GO)

Displaying 1 entry
GO Term
mannose binding

Annotation information from UniProt.

Reference

Displaying **all 3** entries
PubMed ID	Title	First Author
8724140	Forssman disaccharide is the specific ligand of a galectin from the sponge Geodia cydonium but does not mediate its binding to nuclear protein np56.	Hanisch FG
15985430	Involvement of inflammation, degradation, and apoptosis in a mouse model of glaucoma.	Zhou X
27236198	Differentiation-related glycan epitopes identify discrete domains of the muscle glycocalyx.	McMorran BJ

Lectin Frontier DataBase (LfDB)

GlyTouCan: G51497IR
V-V₀: 24.8

GlyTouCan: G39932JF
V-V₀: 13.94

GlyTouCan: G86157UQ
V-V₀: 5.79

LfDB provides quantitative interaction data in terms of the affinity constants (K_a) of a series of lectins toward a panel of pyridylaminated (PA) glycans obtained by an automated frontal affinity chromatography with fluorescence detection (FAC-FD) system. Since the data are accurate and reliable, providing the absolute values of sugar-protein interactions, LfDB would be a valuable resource in the studies of glycan-related biology.

The MCAW profile of the top three glycans above, which resulted from FAC analysis.

UniLectin

UniProt
P05045

CarboGrove

Lectin Name: Dolichos Biflorus Agglutinin
Common Name: DBA

Automated Analysis report (Top 10 high affinity glycans)

Array Source

CFG

Protein Source

Vector

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G97834OQ	1598.48	294.44
G80062GG	1311.88	361.31
G08157XK	1002.46	54.37
G19687OL	189.75	31.11
G09520ZQ	156.31	8.12
G96881BQ	147.15	74.11
G18988VX	125.43	28.46
G42463OP	111.49	18.5
G52724WY	109.85	5.02
G25707UW	105.73	11.17

GlyTouCan ID	Binding Intensity	Stdev
G08157XK	5176.69	408.14
G80062GG	5104.39	4087.59
G97834OQ	4932.63	2779.25
G58980LZ	480.75	39.02
G19687OL	416.28	30.41
G25707UW	344.95	102.45
G09520ZQ	339.88	42.81
G41052GC	255.83	139.59
G00052MO	196.32	49.83
G73932YR	188.78	23.25

GlyTouCan ID	Binding Intensity	Stdev
G80062GG	23064.5	1069.51
G97834OQ	18817.15	944.16
G08157XK	15250.48	193.97
G79389NT	10826	292.74
G41052GC	7664	270.51
G36698XD	683.57	56.88
G26298FT	652.57	60.87
G88274ER	646.21	64.9
G41052GC	577.93	626.58
G09520ZQ	311.87	65.1

GlyTouCan ID	Binding Intensity	Stdev
G80062GG	29632.21	3264.38
G97834OQ	28979.22	764.33
G08157XK	25385.72	1746.88
G79389NT	22707.85	2251.04
G41052GC	20901.45	905.46
G41052GC	16240.02	1120.56
G74353FF	4749.63	294.44
G46503KK	4433.61	1629.92
G00052MO	3874.69	657.79
G26298FT	2494.3	499.57

CarboGrove View

Array Source

Microbial

Protein Source

Vector

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G88108BY	30677.5	1200.67
G75291AO	19652	2020.2
G57321FI	12310.5	400.22
G02657AK	5588	647
G57321FI	1519.5	72.12
G57321FI	1423	374.06
G58896AZ	494	13.44
G08772KU	361	23.33
G04941YC	291	7.78
G26156WV	218	20.51

GlyTouCan ID	Binding Intensity	Stdev
G88108BY	30677.5	1200.67
G75291AO	19652	2020.2
G57321FI	12310.5	400.22
G02657AK	5588	647
G57321FI	1519.5	72.12
G57321FI	1423	374.06
G58896AZ	494	13.44
G08772KU	361	23.33
G04941YC	291	7.78
G26156WV	218	20.51

CarboGrove View

Array Source

NCFG

Protein Source

Vector

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G08157XK	32466	4663
G80062GG	24727	2945
G97834OQ	6816	562
G79389NT	3054	325
G41052GC	2050	608
G41052GC	1046	31
G19687OL	430	36
G80966KZ	320	9
G42463OP	288	18
G09588MX	271	65

GlyTouCan ID	Binding Intensity	Stdev
G08157XK	33928	1647
G80062GG	33656	3004
G79389NT	26094	2158
G97834OQ	21055	882
G41052GC	14715	3526
G41052GC	11535	324
G93612YS	1577	119
G19687OL	562	73
G26298FT	535	13
G80966KZ	385	20

CarboGrove View

Array Source

ZBiotech

Protein Source

Vector

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G19524AS	40593.17	0
G66163TI	34120.17	0
G17480GI	28707.34	0
G02710ET	23042.67	0
G74353FF	18405	0
G00066MO	16695.17	0
G99315PE	12706.67	0
G61168WC	10691.34	0
G88609PK	1622.84	0
G90789UO	1395.84	0

CarboGrove View

Array Source

ZBiotech

Protein Source

Vector

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G48059CD	16490.5	1407.85
G51331BY	4188.25	190.57
G88393MK	3465	2428.21
G45827GY	1693.75	276.83
G74621DY	1540.25	145.31
G10422IZ	983.75	466.34
G55205ZV	288.75	218.85
G87315SO	215.5	66.47
G78436BB	86.5	36.06
G95341UA	72.5	6.36

CarboGrove View

CarboGrove is populated with the results from 35 types of glycan arrays, 13 glycan families, 5 experimental methods, and 19 laboratories or companies by processing and interpreting data from various types of glycan arrays.

PDB

1BJQ

1LU1

1LU2

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

Lectin Frontier DataBase (LfDB)

CarboGrove

PDB

International Collaboration

Acknowledgements

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

Lectin Frontier DataBase (LfDB)

CarboGrove

0.1

1

10

100

50

50

1

10

10

10

PDB

International Collaboration

Acknowledgements