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Hexokinase-1

Summary

Organism: Homo sapiens (human)

External Links

UniProt: P19367

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Allosteric enzyme
Alternative splicing
Charcot-Marie-Tooth disease
Cytoplasm
Direct protein sequencing
Disease variant
Glycolysis
Inflammatory response
Innate immunity
Intellectual disability
Kinase
Mitochondrion outer membrane
Neurodegeneration
Phosphoprotein
Reference proteome
Repeat
Retinitis pigmentosa

Gene Ontology (GO)

Displaying entries **1 - 10** of 14 in total

1

2

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GO Term
mannose metabolic process
positive regulation of cytokine production involved in immune response
glucose metabolic process
glycolytic process
inflammatory response
innate immune response
intracellular glucose homeostasis
fructose 6-phosphate metabolic process
positive regulation of interleukin-1 beta production
carbohydrate phosphorylation

Displaying **all 4** entries
GO Term
cytosol
mitochondrion
mitochondrial outer membrane
membrane raft

Displaying **all 8** entries
GO Term
peptidoglycan binding
ATP binding
glucokinase activity
hexokinase activity
glucose binding
fructokinase activity
mannokinase activity
glucosamine kinase activity

Annotation information from UniProt.

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Defective HK1 causes hexokinase deficiency (HK deficiency)	Homo sapiens
Glycolysis	Homo sapiens
Synthesis of GDP-mannose	Homo sapiens

MCAW-DB (Glycan Recognition Profile)

MCAW-DB is a database whereby users can view the multiple alignment analysis results obtained from the MCAW tool, which can computationally find common glycan substructures among a group of glycan structures. The data in MCAW-DB are analysis results of glycan array experiments; those glycans having higher binding affinity to glycan binding proteins (GBPs) have been analyzed and can be viewed as “glycan recognition profiles”. Currently, this database provides published analysis results of glycan array data from the Consortium for Functional Glycomics (CFG).