GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	Short Names	Lectin Name All	UniProt ID	PDB IDs ▲	LfDB IDs	Monosaccharide Specificities	Species	Taxonomy ID	MCAW IDs	GO Labels	GO IDs
GL_002303	Concanavalin-A	ConA	ConA Concanavalin-A	P02866	1APN 1BXH 1C57 1CES 1CJP 1CN1 1CON 1CVN 1DQ0 1DQ1 1DQ2 1DQ4 1DQ5 1DQ6 1ENQ 1ENR 1ENS 1GIC 1GKB 1HQW 1I3H 1JBC 1JN2 1JOJ 1JUI 1JW6 1JYC 1JYI 1NLS 1NXD 1ONA 1QGL 1QNY 1SCR 1SCS 1TEI 1VAL 1VAM 1XQN 2CNA 2CTV 2ENR 2UU8 2YZ4 3CNA 3D4K 3ENR 3NWK 4P9W 4P9X 4P9Y 4PF5 5CNA 5O6N 5WEY 5Z5L 5Z5N 5Z5P 5Z5Y 5ZAC 6AHG 6H2M 6XT6 7MG1 7MG2 7MG3 7MG4 7MG5 7MG6 7MG7 7MG8 7MG9 7MGA 7MGB 7MGC 7MGD	LfDB0170	Glc Man	Canavalia ensiformis	3823	5342	defense response mannose binding metal ion binding regulation of defense response to virus	GO:0005537 GO:0006952 GO:0046872 GO:0050688
GL_000065	Arcelin-1		Arcelin-1	P19329	1AVB			Phaseolus vulgaris	3885		carbohydrate binding defense response nutrient reservoir activity toxin activity	GO:0006952 GO:0030246 GO:0045735 GO:0090729
GL_000688	Lectin	ECorL	ECorL Lectin	P16404	1AX0 1AX1 1AX2 1AXY 1AXZ 1FYU 1LTE 1SFY 3N35 3N36 3N3H	LfDB0198	Gal GalNAc	Erythrina corallodendron	3843		carbohydrate binding	GO:0030246
GL_002372	Concanavalin-Br		Concanavalin-Br	P55915	1AZD 1QDC 1QDO 2CYF 3JU9 4H55 4P14 4PCR 5YGM 6VB8			Canavalia brasiliensis	61861		mannose binding metal ion binding toxin activity	GO:0005537 GO:0046872 GO:0090729
GL_001022	Pulmonary surfactant-associated protein D		Pulmonary surfactant-associated protein D	P35247	1B08 1M7L 1PW9 1PWB 2GGU 2GGX 2ORJ 2ORK 2OS9 2RIA 2RIB 2RIC 2RID 2RIE 3DBZ 3G81 3G83 3G84 3IKN 3IKP 3IKQ 3IKR 4E52 4M17 4M18 5OXR 5OXS			Homo sapiens	9606	1417 1452 1477	carbohydrate binding clathrin-coated endocytic vesicle collagen trimer defense response to bacterium endocytic vesicle endoplasmic reticulum membrane extracellular region extracellular space identical protein binding innate immune response lung alveolus development lysosome macrophage chemotaxis multivesicular body negative regulation of T cell proliferation negative regulation of interleukin-2 production positive regulation of phagocytosis reactive oxygen species metabolic process receptor-mediated endocytosis regulation of cytokine production respiratory gaseous exchange by respiratory system surfactant homeostasis	GO:0001817 GO:0005576 GO:0005581 GO:0005615 GO:0005764 GO:0005771 GO:0005789 GO:0006898 GO:0007585 GO:0030139 GO:0030246 GO:0032703 GO:0042130 GO:0042742 GO:0042802 GO:0043129 GO:0045087 GO:0045334 GO:0048246 GO:0048286 GO:0050766 GO:0072593
GL_002302	C-reactive protein		C-reactive protein	P02741	1B09 1GNH 1LJ7 3L2Y 3PVN 3PVO 7PK9 7PKB 7PKD 7PKE 7PKF 7PKG 7PKH 7TBA			Homo sapiens	9606		acute-phase response calcium ion binding choline binding complement component C1q complex binding defense response to Gram-positive bacterium extracellular region extracellular space identical protein binding inflammatory response innate immune response low-density lipoprotein particle binding low-density lipoprotein particle receptor binding negative regulation of lipid storage negative regulation of macrophage derived foam cell differentiation negative regulation of mononuclear cell proliferation opsonization positive regulation of gene expression positive regulation of superoxide anion generation regulation of interleukin-8 production vasoconstriction	GO:0001849 GO:0005509 GO:0005576 GO:0005615 GO:0006953 GO:0006954 GO:0008228 GO:0010628 GO:0010745 GO:0010888 GO:0030169 GO:0032677 GO:0032930 GO:0032945 GO:0033265 GO:0042310 GO:0042802 GO:0045087 GO:0050750 GO:0050830
GL_001465	ER membrane protein complex subunit 7		ER membrane protein complex subunit 7	Q9NPA0	1B0G 1LP9 2J8U 2JCC 2UWE 6WW7 6Z3W 7ADO 8EOI 8S9S			Homo sapiens	9606		EMC complex carbohydrate binding endoplasmic reticulum membrane membrane protein insertion into ER membrane by stop-transfer membrane-anchor sequence tail-anchored membrane protein insertion into ER membrane	GO:0005789 GO:0016020 GO:0030246 GO:0045050 GO:0071816 GO:0072546
GL_002276	Lectin SCAman (Fragment)		Lectin SCAman (Fragment)	Q9ZP49	1B2P			Hyacinthoides hispanica	81759		response to other organism	GO:0051707
GL_002333	Heat-labile enterotoxin B chain		Heat-labile enterotoxin B chain	P0CK94	1B44 1LTR 2O2L 3EFX			Escherichia coli	562		extracellular region toxin activity	GO:0005576 GO:0090729
GL_000876	Polycystin-1		Polycystin-1	P98161	1B4R 6A70			Homo sapiens	9606		Golgi apparatus Golgi membrane Golgi-associated vesicle membrane Wnt receptor activity anatomical structure morphogenesis basolateral plasma membrane branching morphogenesis of an epithelial tube calcium channel activity calcium channel complex calcium ion transmembrane transport calcium ion transport calcium-independent cell-matrix adhesion carbohydrate binding cartilage condensation cartilage development cation channel complex cell surface cell-cell signaling by wnt cell-matrix adhesion ciliary membrane cilium cytoplasm detection of mechanical stimulus digestive tract development embryonic placenta development endoplasmic reticulum establishment of epithelial cell polarity extracellular exosome genitalia development heart development homophilic cell adhesion via plasma membrane adhesion molecules in utero embryonic development kidney development lateral plasma membrane liver development lung epithelium development lymph vessel morphogenesis membrane mesonephric duct development mesonephric tubule development metanephric ascending thin limb development metanephric collecting duct development metanephric distal tubule morphogenesis metanephric proximal tubule development motile cilium neural tube development nucleus peptidyl-serine phosphorylation placenta blood vessel development plasma membrane polycystin complex positive regulation of cytosolic calcium ion concentration positive regulation of transcription by RNA polymerase II protein domain specific binding protein export from nucleus protein heterotetramerization protein kinase binding receptor signaling pathway via JAK-STAT regulation of G1/S transition of mitotic cell cycle regulation of cell adhesion regulation of cell cycle regulation of mitotic spindle organization regulation of proteasomal protein catabolic process response to fluid shear stress skin development spinal cord development transcription regulator inhibitor activity transmembrane transporter binding	GO:0000139 GO:0001502 GO:0001701 GO:0001822 GO:0001889 GO:0001892 GO:0002133 GO:0005262 GO:0005634 GO:0005737 GO:0005783 GO:0005794 GO:0005886 GO:0005929 GO:0006611 GO:0006816 GO:0007156 GO:0007160 GO:0007161 GO:0007204 GO:0007259 GO:0007507 GO:0009653 GO:0009986 GO:0016020 GO:0016323 GO:0016328 GO:0018105 GO:0019901 GO:0019904 GO:0021510 GO:0021915 GO:0030155 GO:0030246 GO:0030660 GO:0031514 GO:0034405 GO:0034703 GO:0034704 GO:0036303 GO:0042813 GO:0043588 GO:0044325 GO:0045944 GO:0048565 GO:0048754 GO:0048806 GO:0050982 GO:0051216 GO:0051290 GO:0051726 GO:0060170 GO:0060236 GO:0060428 GO:0060674 GO:0061136 GO:0070062 GO:0070588 GO:0072164 GO:0072177 GO:0072205 GO:0072218 GO:0072237 GO:0072287 GO:0090162 GO:0140416 GO:0198738 GO:2000045