GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	Lectin Name All	UniProt ID ▲	PDB IDs	Species	Taxonomy ID	GO Labels	GO IDs
GL_000045	Agglutinin-1	Agglutinin-1	Q9M6E9	2Q3N 2ZR1	Abrus precatorius	3816	carbohydrate binding defense response heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules negative regulation of translation positive regulation of apoptotic process in another organism rRNA N-glycosylase activity toxin activity	GO:0006952 GO:0007157 GO:0017148 GO:0030246 GO:0030598 GO:0044533 GO:0090729
GL_001449	Endoglucanase 5	Endoglucanase 5	Q9M995		Arabidopsis thaliana	3702	carbohydrate binding cell wall organization cellulase activity cellulose catabolic process extracellular region	GO:0005576 GO:0008810 GO:0030245 GO:0030246 GO:0071555
GL_000650	L-type lectin-domain containing receptor kinase S.1	L-type lectin-domain containing receptor kinase S.1	Q9M9E0		Arabidopsis thaliana	3702	ATP binding carbohydrate binding defense response to bacterium defense response to oomycetes phosphorylation plant-type vacuole plasma membrane protein serine kinase activity protein serine/threonine kinase activity	GO:0000325 GO:0002229 GO:0004674 GO:0005524 GO:0005886 GO:0016310 GO:0030246 GO:0042742 GO:0106310
GL_000572	Jacalin-related lectin 2	Jacalin-related lectin 2	Q9MA49		Arabidopsis thaliana	3702	carbohydrate binding	GO:0030246
GL_001695	Lysosomal alpha-glucosidase	Lysosomal alpha-glucosidase	Q9MYM4		Bos taurus	9913	alpha-1,4-glucosidase activity aorta development autolysosome lumen carbohydrate binding cardiac muscle contraction diaphragm contraction glycogen catabolic process glycophagy heart morphogenesis locomotory behavior lysosomal membrane lysosome organization maltose alpha-glucosidase activity muscle cell cellular homeostasis neuromuscular process controlling balance neuromuscular process controlling posture regulation of the force of heart contraction tissue development vacuolar sequestering	GO:0002026 GO:0002086 GO:0003007 GO:0004558 GO:0005765 GO:0005980 GO:0007040 GO:0007626 GO:0009888 GO:0030246 GO:0032450 GO:0035904 GO:0043181 GO:0046716 GO:0050884 GO:0050885 GO:0060048 GO:0061723 GO:0120282
GL_000821	NKG2-D type II integral membrane protein	NKG2-D type II integral membrane protein	Q9MZ37		Pan troglodytes	9598	adaptive immune response carbohydrate binding cell differentiation cell surface external side of plasma membrane natural killer cell mediated cytotoxicity negative regulation of natural killer cell chemotaxis positive regulation of natural killer cell mediated cytotoxicity signaling receptor activity	GO:0002250 GO:0009897 GO:0009986 GO:0030154 GO:0030246 GO:0038023 GO:0042267 GO:0045954 GO:2000502
GL_000806	Natural killer cells antigen CD94	Natural killer cells antigen CD94	Q9MZ41		Pan troglodytes	9598	HLA-E specific inhibitory MHC class Ib receptor activity MHC class I protein complex binding MHC class Ib protein binding, via antigen binding groove adaptive immune response carbohydrate binding external side of plasma membrane natural killer cell mediated immunity negative regulation of T cell mediated cytotoxicity negative regulation of natural killer cell mediated cytotoxicity plasma membrane positive regulation of natural killer cell mediated cytotoxicity protein antigen binding receptor complex stimulatory C-type lectin receptor signaling pathway transmembrane signaling receptor activity	GO:0001915 GO:0002223 GO:0002228 GO:0002250 GO:0004888 GO:0005886 GO:0009897 GO:0023024 GO:0023030 GO:0030246 GO:0043235 GO:0045953 GO:0045954 GO:0062082 GO:1990405
GL_000816	NKG2-A/NKG2-B type II integral membrane protein	NKG2-A/NKG2-B type II integral membrane protein	Q9MZJ3		Macaca mulatta	9544	CD8-positive, gamma-delta intraepithelial T cell differentiation HLA-E specific inhibitory MHC class Ib receptor activity adaptive immune response carbohydrate binding external side of plasma membrane innate immune response negative regulation of T cell mediated cytotoxicity negative regulation of natural killer cell mediated cytotoxicity plasma membrane positive regulation of natural killer cell mediated cytotoxicity stimulatory C-type lectin receptor signaling pathway transmembrane signaling receptor activity	GO:0001915 GO:0002223 GO:0002250 GO:0002305 GO:0004888 GO:0005886 GO:0009897 GO:0030246 GO:0045087 GO:0045953 GO:0045954 GO:0062082
GL_000828	NKG2-D type II integral membrane protein	NKG2-D type II integral membrane protein	Q9MZJ7		Macaca mulatta	9544	adaptive immune response carbohydrate binding cell differentiation cell surface external side of plasma membrane innate immune response positive regulation of natural killer cell mediated cytotoxicity signaling receptor activity	GO:0002250 GO:0009897 GO:0009986 GO:0030154 GO:0030246 GO:0038023 GO:0045087 GO:0045954
GL_000819	NKG2-C type II integral membrane protein	NKG2-C type II integral membrane protein	Q9MZK6		Macaca mulatta	9544	activating MHC class Ib receptor activity adaptive immune response carbohydrate binding external side of plasma membrane innate immune response plasma membrane positive regulation of natural killer cell degranulation positive regulation of natural killer cell mediated cytotoxicity stimulatory C-type lectin receptor signaling pathway transmembrane signaling receptor activity	GO:0002223 GO:0002250 GO:0004888 GO:0005886 GO:0009897 GO:0030246 GO:0043323 GO:0045087 GO:0045954 GO:0062081