GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	Lectin Name All	UniProt ID	PDB IDs	Species	Taxonomy ID	GO Labels	GO IDs
GL_000211	C-type lectin domain-containing protein 88	C-type lectin domain-containing protein 88	Q86NG3		Caenorhabditis elegans	6239	carbohydrate binding external side of plasma membrane	GO:0009897 GO:0030246
GL_001447	Endoglucanase 19	Endoglucanase 19	Q8L7I0		Arabidopsis thaliana	3702	carbohydrate binding cell wall organization cellulase activity cellulose catabolic process extracellular region	GO:0005576 GO:0008810 GO:0030245 GO:0030246 GO:0071555
GL_000315	Chitinase-3-like protein 1	Chitinase-3-like protein 1	Q6TMG6	1SR0 1ZBK 1ZL1 2DPE 2DSU 2DSV 2DSW 2FDM 2G41 2G8Z 2PI6 5Z4V	Ovis aries	9940	activation of NF-kappaB-inducing kinase activity apoptotic process carbohydrate binding carbohydrate metabolic process cellular response to tumor necrosis factor chitin binding cytoplasm endoplasmic reticulum extracellular space inflammatory response lung development perinuclear region of cytoplasm positive regulation of ERK1 and ERK2 cascade positive regulation of angiogenesis positive regulation of interleukin-8 production positive regulation of peptidyl-threonine phosphorylation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction response to interleukin-1 response to interleukin-6 response to mechanical stimulus response to tumor necrosis factor	GO:0005615 GO:0005737 GO:0005783 GO:0005975 GO:0006915 GO:0006954 GO:0007250 GO:0008061 GO:0009612 GO:0010800 GO:0030246 GO:0030324 GO:0032757 GO:0034612 GO:0045766 GO:0048471 GO:0051897 GO:0070374 GO:0070555 GO:0070741 GO:0071356
GL_002008	E-selectin	E-selectin	Q95LG1		Equus caballus	9796	calcium ion binding external side of plasma membrane extracellular space heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte tethering or rolling oligosaccharide binding positive regulation of leukocyte tethering or rolling response to cytokine sialic acid binding	GO:0005509 GO:0005615 GO:0007157 GO:0009897 GO:0033691 GO:0034097 GO:0050901 GO:0070492 GO:1903238
GL_001414	Contactin-1	Contactin-1	P12960	7OL2 7OL4	Mus musculus	10090	Notch signaling pathway axon axon guidance brain development carbohydrate binding cell-cell adhesion cell-cell adhesion mediator activity central nervous system myelin formation cerebellum development gene expression locomotory behavior myelin sheath myelination neuron projection development plasma membrane positive regulation of gene expression positive regulation of neuron projection development positive regulation of peptidyl-tyrosine phosphorylation positive regulation of sodium ion transport postsynaptic membrane presynaptic membrane side of membrane	GO:0005886 GO:0007219 GO:0007411 GO:0007420 GO:0007626 GO:0010467 GO:0010628 GO:0010765 GO:0010976 GO:0021549 GO:0030246 GO:0030424 GO:0031175 GO:0032289 GO:0042552 GO:0042734 GO:0043209 GO:0045211 GO:0050731 GO:0098552 GO:0098609 GO:0098632
GL_001152	Type-2 ice-structuring protein	Type-2 ice-structuring protein	A0ZT93	2ZIB	Brachyopsis segaliensis	1633465	carbohydrate binding extracellular region	GO:0005576 GO:0030246
GL_001464	ER degradation-enhancing alpha-mannosidase-like protein 1	ER degradation-enhancing alpha-mannosidase-like protein 1	O94726		Schizosaccharomyces pombe 972h-	284812	calcium ion binding carbohydrate binding carbohydrate metabolic process cytosol endoplasmic reticulum endoplasmic reticulum lumen membrane response to unfolded protein ubiquitin-dependent glycoprotein ERAD pathway	GO:0005509 GO:0005783 GO:0005788 GO:0005829 GO:0005975 GO:0006986 GO:0016020 GO:0030246 GO:0097466
GL_000879	Polycystin-1-like protein 3	Polycystin-1-like protein 3	Q2EG98	7D7E 7D7F	Mus musculus	10090	calcium channel activity calcium ion binding carbohydrate binding cation channel complex cellular response to acidic pH detection of chemical stimulus involved in sensory perception of sour taste detection of mechanical stimulus membrane monoatomic cation transport plasma membrane receptor complex sensory perception of sour taste transmembrane transporter binding	GO:0001581 GO:0005262 GO:0005509 GO:0005886 GO:0006812 GO:0016020 GO:0030246 GO:0034703 GO:0043235 GO:0044325 GO:0050915 GO:0050982 GO:0071468
GL_001522	Glucans biosynthesis protein D	Glucans biosynthesis protein D	B2U143		Shigella boydii CDC 3083-94	344609	carbohydrate binding catalytic activity glucan biosynthetic process periplasmic space	GO:0003824 GO:0009250 GO:0030246 GO:0042597
GL_001614	Glucans biosynthesis protein G	Glucans biosynthesis protein G	Q3Z375		Shigella sonnei Ss046	300269	carbohydrate binding catalytic activity glucan biosynthetic process periplasmic space	GO:0003824 GO:0009250 GO:0030246 GO:0042597