GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	Lectin Name All ▼	UniProt ID	PDB IDs	Species	Taxonomy ID	GO Labels	GO IDs
GL_001237	Alpha-mannosidase 2x	Alpha-mannosidase 2x	Q8BRK9		Mus musculus	10090	Golgi membrane N-glycan processing alpha-mannosidase activity carbohydrate binding hydrolase activity, hydrolyzing N-glycosyl compounds mannose metabolic process mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity metal ion binding protein glycosylation	GO:0000139 GO:0004559 GO:0004572 GO:0006013 GO:0006486 GO:0006491 GO:0015923 GO:0016799 GO:0030246 GO:0046872
GL_001236	Alpha-mannosidase 2C1	Alpha-mannosidase 2C1	P21139		Rattus norvegicus	10116	alpha-mannosidase activity carbohydrate binding cytosol mannose metabolic process metal ion binding oligosaccharide catabolic process	GO:0004559 GO:0005829 GO:0006013 GO:0009313 GO:0030246 GO:0046872
GL_001234	Alpha-mannosidase 2C1	Alpha-mannosidase 2C1	Q91W89		Mus musculus	10090	alpha-mannosidase activity carbohydrate binding cytosol mannose metabolic process metal ion binding nucleoplasm oligosaccharide catabolic process	GO:0004559 GO:0005654 GO:0005829 GO:0006013 GO:0009313 GO:0030246 GO:0046872
GL_001235	Alpha-mannosidase 2C1	Alpha-mannosidase 2C1	Q9NTJ4		Homo sapiens	9606	alpha-mannosidase activity carbohydrate binding cytosol mannose metabolic process metal ion binding nucleoplasm oligosaccharide catabolic process	GO:0004559 GO:0005654 GO:0005829 GO:0006013 GO:0009313 GO:0030246 GO:0046872
GL_001233	Alpha-mannosidase 2	Alpha-mannosidase 2	O18497		Spodoptera frugiperda	7108	Golgi membrane N-glycan processing carbohydrate binding endoplasmic reticulum mannose metabolic process mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity metal ion binding protein glycosylation	GO:0000139 GO:0004572 GO:0005783 GO:0006013 GO:0006486 GO:0006491 GO:0030246 GO:0046872
GL_001231	Alpha-mannosidase 2	Alpha-mannosidase 2	Q16706		Homo sapiens	9606	Golgi medial cisterna Golgi membrane N-glycan processing alpha-mannosidase activity carbohydrate binding cis-Golgi network extracellular exosome hydrolase activity, hydrolyzing N-glycosyl compounds in utero embryonic development liver development lung alveolus development mannose metabolic process mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity membrane metal ion binding mitochondrion organization positive regulation of neurogenesis protein glycosylation protein homodimerization activity respiratory gaseous exchange by respiratory system retina morphogenesis in camera-type eye vacuole organization viral protein processing	GO:0000139 GO:0001701 GO:0001889 GO:0004559 GO:0004572 GO:0005797 GO:0005801 GO:0006013 GO:0006486 GO:0006491 GO:0007005 GO:0007033 GO:0007585 GO:0016020 GO:0016799 GO:0019082 GO:0030246 GO:0042803 GO:0046872 GO:0048286 GO:0050769 GO:0060042 GO:0070062
GL_001232	Alpha-mannosidase 2	Alpha-mannosidase 2	P27046		Mus musculus	10090	Golgi apparatus Golgi medial cisterna Golgi membrane N-glycan processing alpha-mannosidase activity carbohydrate binding cis-Golgi network extracellular space hydrolase activity hydrolase activity, hydrolyzing N-glycosyl compounds identical protein binding in utero embryonic development liver development lung alveolus development mannose metabolic process mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity metal ion binding mitochondrion organization positive regulation of neurogenesis protein glycosylation protein homodimerization activity respiratory gaseous exchange by respiratory system retina morphogenesis in camera-type eye vacuole organization	GO:0000139 GO:0001701 GO:0001889 GO:0004559 GO:0004572 GO:0005615 GO:0005794 GO:0005797 GO:0005801 GO:0006013 GO:0006486 GO:0006491 GO:0007005 GO:0007033 GO:0007585 GO:0015923 GO:0016787 GO:0016799 GO:0030246 GO:0042802 GO:0042803 GO:0046872 GO:0048286 GO:0050769 GO:0060042
GL_001230	Alpha-mannosidase 2	Alpha-mannosidase 2	P28494		Rattus norvegicus	10116	Golgi apparatus Golgi medial cisterna Golgi membrane N-glycan processing alpha-mannosidase activity carbohydrate binding cis-Golgi network extracellular space hydrolase activity hydrolase activity, hydrolyzing N-glycosyl compounds identical protein binding in utero embryonic development liver development lung alveolus development mannose metabolic process mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity mitochondrion organization positive regulation of neurogenesis protein glycosylation protein homodimerization activity respiratory gaseous exchange by respiratory system retina morphogenesis in camera-type eye vacuole organization zinc ion binding	GO:0000139 GO:0001701 GO:0001889 GO:0004559 GO:0004572 GO:0005615 GO:0005794 GO:0005797 GO:0005801 GO:0006013 GO:0006486 GO:0006491 GO:0007005 GO:0007033 GO:0007585 GO:0008270 GO:0015923 GO:0016787 GO:0016799 GO:0030246 GO:0042802 GO:0042803 GO:0048286 GO:0050769 GO:0060042
GL_001228	Alpha-mannosidase 2	Alpha-mannosidase 2	Q24451	1HTY 1HWW 1HXK 1PS3 1QWN 1QWU 1QX1 1R33 1R34 1TQS 1TQT 1TQU 1TQV 1TQW 2ALW 2F18 2F1A 2F1B 2F7O 2F7P 2F7Q 2F7R 2FYV 2OW6 2OW7 3BLB 3BUB 3BUD 3BUI 3BUP 3BUQ 3BVT 3BVU 3BVV 3BVW 3BVX 3CV5 3CZN 3CZS 3D4Y 3D4Z 3D50 3D51 3D52 3DDF 3DDG 3DX0 3DX1 3DX2 3DX3 3DX4 3EJP 3EJQ 3EJR 3EJS 3EJT 3EJU 6RPC 6RQZ 6RRH 6RRJ 6RRN 6RRU 6RRW 6RRX 6RRY 6RS0	Drosophila melanogaster	7227	Golgi membrane Golgi stack N-glycan processing alpha-mannosidase activity carbohydrate binding encapsulation of foreign target endoplasmic reticulum mannose metabolic process mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity metal ion binding protein deglycosylation protein glycosylation rhodopsin biosynthetic process	GO:0000139 GO:0004559 GO:0004572 GO:0005783 GO:0005795 GO:0006013 GO:0006486 GO:0006491 GO:0006517 GO:0015923 GO:0016063 GO:0030246 GO:0035010 GO:0046872
GL_001229	Alpha-mannosidase 2	Alpha-mannosidase 2	Q9LFR0		Arabidopsis thaliana	3702	Golgi apparatus Golgi cis cisterna Golgi membrane alpha-mannosidase activity carbohydrate binding endosome hyperosmotic salinity response mannose metabolic process mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity metal ion binding protein N-linked glycosylation trans-Golgi network	GO:0000137 GO:0000139 GO:0004559 GO:0004572 GO:0005768 GO:0005794 GO:0005802 GO:0006013 GO:0006487 GO:0030246 GO:0042538 GO:0046872