GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	Lectin Name All	UniProt ID	PDB IDs	Species	Taxonomy ID ▼	MCAW IDs	GO Labels	GO IDs
GL_000145	C-type lectin domain family 12 member B	C-type lectin domain family 12 member B	Q149M0		Mus musculus	10090		carbohydrate binding external side of plasma membrane melanocyte proliferation natural killer cell inhibitory signaling pathway negative regulation of natural killer cell mediated cytotoxicity negative regulation of receptor signaling pathway via STAT protein phosphatase binding protein-containing complex signaling receptor inhibitor activity	GO:0002769 GO:0009897 GO:0019903 GO:0030246 GO:0030547 GO:0032991 GO:0045953 GO:0097325 GO:1904893
GL_001639	Glycogen phosphorylase, brain form	Glycogen phosphorylase, brain form	Q8CI94		Mus musculus	10090		SHG alpha-glucan phosphorylase activity axon carbohydrate binding cytoplasm glycogen catabolic process glycogen metabolic process glycogen phosphorylase activity identical protein binding linear malto-oligosaccharide phosphorylase activity organic cyclic compound binding pyridoxal phosphate binding	GO:0005737 GO:0005977 GO:0005980 GO:0008184 GO:0030170 GO:0030246 GO:0030424 GO:0042802 GO:0097159 GO:0102250 GO:0102499
GL_001946	C-type lectin domain family 4, member a4	C-type lectin domain family 4, member a4	Q5YIR8	3VYJ 3VYK	Mus musculus	10090		antifungal innate immune response calcium ion binding carbohydrate binding carbohydrate derivative binding external side of plasma membrane mannose binding	GO:0005509 GO:0005537 GO:0009897 GO:0030246 GO:0061760 GO:0097367
GL_000319	Chondrolectin	Chondrolectin	Q9CXM0		Mus musculus	10090		carbohydrate binding centrosome cytoplasm cytosol membrane nervous system development perinuclear region of cytoplasm positive regulation of axonogenesis regulation of neuron projection development	GO:0005737 GO:0005813 GO:0005829 GO:0007399 GO:0010975 GO:0016020 GO:0030246 GO:0048471 GO:0050772
GL_000781	Myeloid cell surface antigen CD33	Myeloid cell surface antigen CD33	Q63994		Mus musculus	10090		Golgi apparatus carbohydrate binding cell adhesion cell surface cytosol external side of plasma membrane nucleoplasm peroxisome plasma membrane protein phosphatase binding sialic acid binding	GO:0005654 GO:0005777 GO:0005794 GO:0005829 GO:0005886 GO:0007155 GO:0009897 GO:0009986 GO:0019903 GO:0030246 GO:0033691
GL_002067	Regenerating islet-derived protein 3-gamma	Regenerating islet-derived protein 3-gamma	O09049		Mus musculus	10090		MyD88-dependent toll-like receptor signaling pathway acute-phase response antimicrobial humoral immune response mediated by antimicrobial peptide collagen-containing extracellular matrix defense response to Gram-negative bacterium defense response to Gram-positive bacterium extracellular space hormone activity metal ion binding negative regulation of inflammatory response negative regulation of inflammatory response to wounding negative regulation of keratinocyte differentiation oligosaccharide binding peptidoglycan binding positive regulation of cell population proliferation positive regulation of detection of glucose positive regulation of keratinocyte proliferation positive regulation of wound healing response to bacterium response to peptide hormone response to symbiotic bacterium secretory granule signaling receptor activity	GO:0002755 GO:0005179 GO:0005615 GO:0006953 GO:0008284 GO:0009609 GO:0009617 GO:0010838 GO:0030141 GO:0038023 GO:0042834 GO:0043434 GO:0045617 GO:0046872 GO:0050728 GO:0050829 GO:0050830 GO:0061844 GO:0062023 GO:0070492 GO:0090303 GO:0106015 GO:2000972
GL_000484	Galectin-10 (Fragment)	Galectin-10 (Fragment)	P97400		Mus musculus	10090		T cell apoptotic process carbohydrate binding cysteine-type endopeptidase activity involved in apoptotic process cytosol regulation of T cell anergy regulation of T cell cytokine production regulation of activated T cell proliferation	GO:0002667 GO:0002724 GO:0005829 GO:0030246 GO:0046006 GO:0070231 GO:0097153
GL_000958	Prostatic spermine-binding protein	Prostatic spermine-binding protein	P15501		Mus musculus	10090		carbohydrate binding extracellular region extracellular space	GO:0005576 GO:0005615 GO:0030246
GL_001502	Galactose mutarotase	Galactose mutarotase	Q8K157		Mus musculus	10090		aldose 1-epimerase activity carbohydrate binding carbohydrate metabolic process cytoplasm galactose catabolic process via UDP-galactose galactose metabolic process glucose metabolic process	GO:0004034 GO:0005737 GO:0005975 GO:0006006 GO:0006012 GO:0030246 GO:0033499
GL_002073	Sialic acid-binding Ig-like lectin 12	Sialic acid-binding Ig-like lectin 12	Q91Y57		Mus musculus	10090	5403	cell adhesion external side of plasma membrane inflammatory response membrane monosaccharide binding negative regulation of inflammatory response negative regulation of phagocytosis, engulfment phagocytosis, engulfment plasma membrane sialic acid binding	GO:0005886 GO:0006911 GO:0006954 GO:0007155 GO:0009897 GO:0016020 GO:0033691 GO:0048029 GO:0050728 GO:0060101