GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	Lectin Name All	UniProt ID	PDB IDs	Species	Taxonomy ID	GO Labels	GO IDs
GL_000782	Myeloid cell surface antigen CD33	Myeloid cell surface antigen CD33	P20138	5IHB 5J06 5J0B 6D48 6D49 6D4A 6TL8 7AW6	Homo sapiens	9606	Golgi apparatus carbohydrate binding cell adhesion cell surface cell-cell adhesion cell-cell signaling external side of plasma membrane immune response-inhibiting signal transduction negative regulation of calcium ion transport negative regulation of cell population proliferation negative regulation of interleukin-1 beta production negative regulation of interleukin-8 production negative regulation of monocyte activation negative regulation of tumor necrosis factor production nucleoplasm peroxisome plasma membrane positive regulation of protein secretion positive regulation of protein tyrosine phosphatase activity protein phosphatase binding sialic acid binding signal transduction signaling receptor activity specific granule membrane tertiary granule membrane	GO:0002765 GO:0005654 GO:0005777 GO:0005794 GO:0005886 GO:0007155 GO:0007165 GO:0007267 GO:0008285 GO:0009897 GO:0009986 GO:0019903 GO:0030246 GO:0032691 GO:0032717 GO:0032720 GO:0033691 GO:0035579 GO:0038023 GO:0050714 GO:0051926 GO:0070821 GO:0098609 GO:0150102 GO:1903615
GL_002003	E-selectin	E-selectin	P98107		Bos taurus	9913	actin filament-based process calcium ion binding caveola clathrin-coated pit cortical cytoskeleton external side of plasma membrane extracellular space heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte tethering or rolling oligosaccharide binding perinuclear region of cytoplasm phospholipase binding positive regulation of leukocyte migration positive regulation of leukocyte tethering or rolling positive regulation of receptor internalization response to cytokine response to interleukin-1 sialic acid binding transmembrane signaling receptor activity	GO:0002092 GO:0002687 GO:0004888 GO:0005509 GO:0005615 GO:0005901 GO:0005905 GO:0007157 GO:0009897 GO:0030029 GO:0030863 GO:0033691 GO:0034097 GO:0043274 GO:0048471 GO:0050901 GO:0070492 GO:0070555 GO:1903238
GL_002242	Agglutinin	Agglutinin	Q7Y041	8A9M	Hippeastrum vittatum	231486	response to other organism	GO:0051707
GL_001880	Uncharacterized isomerase YNR071C	Uncharacterized isomerase YNR071C	P53757	1YGA	Saccharomyces cerevisiae S288C	559292	aldose 1-epimerase activity carbohydrate binding galactose catabolic process via UDP-galactose glucose metabolic process	GO:0004034 GO:0006006 GO:0030246 GO:0033499
GL_002054	Protein ERGIC-53	Protein ERGIC-53	Q62902	1GV9 1R1Z	Rattus norvegicus	10116	COPII-coated ER to Golgi transport vesicle Golgi apparatus Golgi membrane Golgi organization calcium ion binding endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum organization endoplasmic reticulum to Golgi vesicle-mediated transport endoplasmic reticulum-Golgi intermediate compartment endoplasmic reticulum-Golgi intermediate compartment membrane identical protein binding mannose binding metal ion binding positive regulation of organelle organization protein transport sarcomere	GO:0000139 GO:0005509 GO:0005537 GO:0005783 GO:0005789 GO:0005793 GO:0005794 GO:0006888 GO:0007029 GO:0007030 GO:0010638 GO:0015031 GO:0030017 GO:0030134 GO:0033116 GO:0042802 GO:0046872
GL_001319	Beta-galactosidase	Beta-galactosidase	B7UJI9		Escherichia coli O127:H6 str. E2348/69	574521	beta-galactosidase activity beta-galactosidase complex carbohydrate binding carbohydrate metabolic process magnesium ion binding organic substance catabolic process	GO:0000287 GO:0004565 GO:0005975 GO:0009341 GO:0030246 GO:1901575
GL_001094	Seed lectin	Seed lectin	P81371	4U2A 4U36 4WV8 4XTM 4XTP 4XXA	Vatairea macrocarpa	77050	carbohydrate binding metal ion binding	GO:0030246 GO:0046872
GL_001539	Glucans biosynthesis protein D	Glucans biosynthesis protein D	Q4KHN0		Pseudomonas protegens Pf-5	220664	carbohydrate binding catalytic activity glucan biosynthetic process periplasmic space	GO:0003824 GO:0009250 GO:0030246 GO:0042597
GL_000557	Intelectin-1a	Intelectin-1a	O88310		Mus musculus	10090	brush border membrane calcium ion binding carbohydrate binding collagen-containing extracellular matrix extracellular space identical protein binding membrane raft oligosaccharide binding positive regulation of glucose import positive regulation of protein phosphorylation protein homotrimerization receptor complex response to nematode side of membrane	GO:0001934 GO:0005509 GO:0005615 GO:0009624 GO:0030246 GO:0031526 GO:0042802 GO:0043235 GO:0045121 GO:0046326 GO:0062023 GO:0070207 GO:0070492 GO:0098552
GL_001483	F-box protein PP2-A14	F-box protein PP2-A14	Q9FJ80		Arabidopsis thaliana	3702	carbohydrate binding nucleus protein ubiquitination	GO:0005634 GO:0016567 GO:0030246