GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	Short Names ▲	Lectin Name All	UniProt ID	PDB IDs	LfDB IDs	Monosaccharide Specificities	Species	Taxonomy ID	MCAW IDs	GO Labels	GO IDs
GL_000688	Lectin	ECorL	ECorL Lectin	P16404	1AX0 1AX1 1AX2 1AXY 1AXZ 1FYU 1LTE 1SFY 3N35 3N36 3N3H	LfDB0198	Gal GalNAc	Erythrina corallodendron	3843		carbohydrate binding	GO:0030246
GL_002417	Lectin 2	EEA EEL	EEA EEL Lectin 2	B3SV75		LfDB0222	Others	Euonymus europaeus	123417
GL_002416	Lectin 1	EEA EEL	EEA EEL Lectin 1	B3SV73		LfDB0222	Others	Euonymus europaeus	123417
GL_001937	29-kDa galactose-binding lectin	EW29	EW29 29-kDa galactose-binding lectin	O96048	2DRY 2DRZ 2DS0 2RST 2ZQN 2ZQO	LfDB0357		Lumbricus terrestris	6398		carbohydrate binding	GO:0030246
GL_002361	Mannose-specific lectin	GNA GNL	GNA GNL Mannose-specific lectin	P30617	1JPC 1MSA 1NIV	LfDB0206	Man	Galanthus nivalis	4670		defense response extracellular region mannose binding regulation of defense response to virus response to virus	GO:0005537 GO:0005576 GO:0006952 GO:0009615 GO:0050688
GL_001959	GSI-B4 isolectin (Fragment)	GS-I GSL-I GSL-l B4	GS-I GSL-I GSL-l B4 GSI-B4 isolectin (Fragment)	Q8W1R6	1GNZ 1HQL	LfDB0223 LfDB0230	Gal GalNAc	Griffonia simplicifolia	3850		carbohydrate binding metal ion binding	GO:0030246 GO:0046872
GL_001972	Insecticidal N-acetylglucosamine-specific lectin (Fragment)	GS-II GSL-II	GS-II GSL-II Insecticidal N-acetylglucosamine-specific lectin (Fragment)	Q41263		LfDB0176	GlcNAc	Griffonia simplicifolia	3850		carbohydrate binding	GO:0030246
GL_001974	GSI-A4 isolectin (Fragment)	GSL-l A4	GSL-l A4 GSI-A4 isolectin (Fragment)	Q8W1R7		LfDB0229	Gal GalNAc	Griffonia simplicifolia	3850		carbohydrate binding	GO:0030246
GL_000491	Galectin-3	Gal3 Galectin-3 (Human)	Gal3 Galectin-3 (Human) Galectin-3	P17931	1A3K 1KJL 1KJR 2NMN 2NMO 2NN8 2XG3 3AYA 3AYC 3AYD 3AYE 3T1L 3T1M 3ZSJ 3ZSK 3ZSL 3ZSM 4BLI 4BLJ 4BM8 4JC1 4JCK 4LBJ 4LBK 4LBL 4LBM 4LBN 4LBO 4R9A 4R9B 4R9C 4R9D 4RL7 4XBN 5E88 5E89 5E8A 5EXO 5H9P 5H9R 5IUQ 5NF7 5NF9 5NFA 5NFB 5NFC 5OAX 5ODY 6B8K 6EOG 6EOL 6EXY 6EYM 6F2Q 6F6Y 6FK2 6FOF 6G0V 6H64 6I74 6I75 6I76 6I77 6I78 6KXA 6KXB 6Q0Q 6Q17 6QGE 6QGF 6QLN 6QLO 6QLP 6QLQ 6QLR 6QLS 6QLT 6QLU 6RHL 6RHM 6RZF 6RZG 6RZH 6RZI 6RZJ 6RZK 6RZL 6RZM 6TF6 6TF7 6Y4C 6Y78 6ZVF 7BE3 7CXA 7DF5 7RDO 7RDP 7RGX 7RGY 7RGZ 7RH0 7RH1 7RH3 7RH4 7XFA 7ZQX 8BZ3 8OJI 8OJK 8OJM 8OJO 8PPN	LfDB0056 LfDB0065	Gal	Homo sapiens	9606	103 104 106 107 108 115 116 5108	IgE binding RNA binding RNA splicing carbohydrate binding cell surface chemoattractant activity collagen-containing extracellular matrix cytoplasm cytosol eosinophil chemotaxis epithelial cell differentiation extracellular exosome extracellular region extracellular space ficolin-1-rich granule membrane immunological synapse innate immune response laminin binding mRNA processing macrophage chemotaxis membrane mitochondrial inner membrane molecular condensate scaffold activity monocyte chemotaxis mononuclear cell migration negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell negative regulation of T cell receptor signaling pathway negative regulation of endocytosis negative regulation of extrinsic apoptotic signaling pathway negative regulation of immunological synapse formation negative regulation of protein tyrosine phosphatase activity neutrophil chemotaxis nucleoplasm nucleus plasma membrane positive chemotaxis positive regulation of calcium ion import positive regulation of mononuclear cell migration positive regulation of protein localization to plasma membrane positive regulation of protein-containing complex assembly protein phosphatase binding protein phosphatase inhibitor activity regulation of T cell apoptotic process regulation of T cell proliferation regulation of extrinsic apoptotic signaling pathway via death domain receptors secretory granule membrane spliceosomal complex	GO:0001772 GO:0002548 GO:0003723 GO:0004864 GO:0005576 GO:0005615 GO:0005634 GO:0005654 GO:0005681 GO:0005737 GO:0005743 GO:0005829 GO:0005886 GO:0006397 GO:0008380 GO:0009986 GO:0016020 GO:0019863 GO:0019903 GO:0030246 GO:0030593 GO:0030667 GO:0030855 GO:0031334 GO:0042056 GO:0042129 GO:0043236 GO:0045087 GO:0045806 GO:0048245 GO:0048246 GO:0050860 GO:0050918 GO:0062023 GO:0070062 GO:0070232 GO:0071674 GO:0071677 GO:0090280 GO:0101003 GO:0140693 GO:1902041 GO:1903078 GO:1903614 GO:2000521 GO:2001189 GO:2001237
GL_000469	Galectin-1	Galectin-1	Galectin-1 Galectin-1	P09382	1GZW 1W6M 1W6N 1W6O 1W6P 1W6Q 2KM2 2ZKN 3OY8 3OYW 3T2T 3W58 3W59 4Q1P 4Q1R 4Q26 4Q27 4Q2F 4XBL 4Y1U 4Y1V 4Y1X 4Y1Y 4Y1Z 4Y20 4Y22 4Y24 5MWT 5MWX 6B94 6F83 6M5Y 7LTA 7NML 8B0W 8B0Z	LfDB0270		Homo sapiens	9606	1273 1290 1291 1292 1720 1723 1724 1725 295 296 2985 2989 2991 2992 2993 2996 416 417 5109	RNA binding T cell costimulation apoptotic process carbohydrate binding cell-cell adhesion collagen-containing extracellular matrix cytoplasm cytosol endoplasmic reticulum lumen extracellular exosome extracellular region extracellular space galectin complex laminin binding myoblast differentiation plasma cell differentiation positive regulation of apoptotic process positive regulation of canonical NF-kappaB signal transduction positive regulation of inflammatory response positive regulation of viral entry into host cell regulation of apoptotic process	GO:0002317 GO:0003723 GO:0005576 GO:0005615 GO:0005737 GO:0005788 GO:0005829 GO:0006915 GO:0030246 GO:0031295 GO:0042981 GO:0043065 GO:0043123 GO:0043236 GO:0045445 GO:0046598 GO:0050729 GO:0062023 GO:0070062 GO:0098609 GO:1990724