GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	Lectin Name All	UniProt ID	PDB IDs	Species	Taxonomy ID ▼	GO Labels	GO IDs
GL_001896	Zona pellucida sperm-binding protein 3	Zona pellucida sperm-binding protein 3	P48830		Bos taurus	9913	acrosin binding binding of sperm to zona pellucida blastocyst formation carbohydrate binding collagen-containing extracellular matrix egg coat egg coat formation extracellular matrix extracellular space humoral immune response mediated by circulating immunoglobulin negative regulation of DNA-templated transcription oocyte development plasma membrane positive regulation of DNA-templated transcription positive regulation of T cell proliferation positive regulation of acrosomal vesicle exocytosis positive regulation of acrosome reaction positive regulation of antral ovarian follicle growth positive regulation of humoral immune response positive regulation of inflammatory response positive regulation of interleukin-4 production positive regulation of leukocyte migration positive regulation of ovarian follicle development positive regulation of type II interferon production positive regulation of type IV hypersensitivity protein-containing complex receptor ligand activity structural constituent of egg coat	GO:0001809 GO:0001825 GO:0002455 GO:0002687 GO:0002922 GO:0005615 GO:0005886 GO:0007339 GO:0030246 GO:0031012 GO:0032190 GO:0032729 GO:0032753 GO:0032991 GO:0035803 GO:0035804 GO:0035805 GO:0042102 GO:0045892 GO:0045893 GO:0048018 GO:0048599 GO:0050729 GO:0062023 GO:2000344 GO:2000368 GO:2000386 GO:2000388
GL_001144	Tetranectin	Tetranectin	Q2KIS7		Bos taurus	9913	bone mineralization calcium ion binding carbohydrate binding cytoplasm extracellular space granular component heparin binding ossification positive regulation of plasminogen activation	GO:0001503 GO:0001652 GO:0005509 GO:0005615 GO:0005737 GO:0008201 GO:0010756 GO:0030246 GO:0030282
GL_000977	Protein FAM3C	Protein FAM3C	A5PKI3		Bos taurus	9913	carbohydrate binding cytoplasmic vesicle extracellular space	GO:0005615 GO:0030246 GO:0031410
GL_000147	C-type lectin domain family 12 member B	C-type lectin domain family 12 member B	Q2NL33		Bos taurus	9913	carbohydrate binding external side of plasma membrane melanocyte proliferation natural killer cell inhibitory signaling pathway negative regulation of receptor signaling pathway via STAT protein phosphatase binding signaling receptor regulator activity	GO:0002769 GO:0009897 GO:0019903 GO:0030246 GO:0030545 GO:0097325 GO:1904893
GL_002326	Cation-independent mannose-6-phosphate receptor	Cation-independent mannose-6-phosphate receptor	P08169	1Q25 1SYO 1SZ0 2KVA 2KVB 6UM1 6UM2	Bos taurus	9913	Golgi apparatus Golgi membrane cell surface endocytic vesicle endosome membrane insulin-like growth factor binding kringle domain binding late endosome lysosomal transport mannose binding phosphoprotein binding plasma membrane signaling receptor activity trans-Golgi network	GO:0000139 GO:0005520 GO:0005537 GO:0005770 GO:0005794 GO:0005802 GO:0005886 GO:0007041 GO:0009986 GO:0010008 GO:0030139 GO:0036143 GO:0038023 GO:0051219
GL_002028	L-selectin	L-selectin	P98131		Bos taurus	9913	calcium ion binding calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules cell adhesion external side of plasma membrane extracellular space heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte tethering or rolling membrane oligosaccharide binding plasma membrane response to cytokine sialic acid binding	GO:0005509 GO:0005615 GO:0005886 GO:0007155 GO:0007157 GO:0009897 GO:0016020 GO:0016339 GO:0033691 GO:0034097 GO:0050901 GO:0070492
GL_001170	Versican core protein	Versican core protein	P81282		Bos taurus	9913	calcium ion binding carbohydrate binding cell adhesion central nervous system development extracellular region extracellular space glial cell differentiation hyaluronic acid binding interphotoreceptor matrix perineuronal net photoreceptor outer segment positive regulation of neuroblast proliferation skeletal system development synapse	GO:0001501 GO:0001750 GO:0002052 GO:0005509 GO:0005540 GO:0005576 GO:0005615 GO:0007155 GO:0007417 GO:0010001 GO:0030246 GO:0033165 GO:0045202 GO:0072534
GL_001023	Pulmonary surfactant-associated protein D	Pulmonary surfactant-associated protein D	P35246		Bos taurus	9913	carbohydrate binding collagen trimer extracellular space innate immune response lung alveolus development multivesicular body positive regulation of phagocytosis respiratory gaseous exchange by respiratory system surfactant homeostasis	GO:0005581 GO:0005615 GO:0005771 GO:0007585 GO:0030246 GO:0043129 GO:0045087 GO:0048286 GO:0050766
GL_002003	E-selectin	E-selectin	P98107		Bos taurus	9913	actin filament-based process calcium ion binding caveola clathrin-coated pit cortical cytoskeleton external side of plasma membrane extracellular space heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte tethering or rolling oligosaccharide binding perinuclear region of cytoplasm phospholipase binding positive regulation of leukocyte migration positive regulation of leukocyte tethering or rolling positive regulation of receptor internalization response to cytokine response to interleukin-1 sialic acid binding transmembrane signaling receptor activity	GO:0002092 GO:0002687 GO:0004888 GO:0005509 GO:0005615 GO:0005901 GO:0005905 GO:0007157 GO:0009897 GO:0030029 GO:0030863 GO:0033691 GO:0034097 GO:0043274 GO:0048471 GO:0050901 GO:0070492 GO:0070555 GO:1903238
GL_000515	Galectin-9	Galectin-9	Q3MHZ8		Bos taurus	9913	carbohydrate binding cytosol extracellular region galactoside binding immune system process negative regulation of CD4-positive, alpha-beta T cell proliferation negative regulation of type II interferon production nucleus positive regulation of gene expression	GO:0002376 GO:0005576 GO:0005634 GO:0005829 GO:0010628 GO:0016936 GO:0030246 GO:0032689 GO:2000562