GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	Short Names	Lectin Name All	UniProt ID	PDB IDs	LfDB IDs ▲	Monosaccharide Specificities	Species	Taxonomy ID	MCAW IDs	GO Labels	GO IDs
GL_001382	CD209 antigen	DC-SIGN LSECtin CRD Fc	DC-SIGN LSECtin CRD Fc CD209 antigen	Q9NNX6	1K9I 1SL4 1SL5 2B6B 2IT5 2IT6 2XR5 2XR6 6GHV 7NL6 7NL7	LfDB0019 LfDB0277	Man	Homo sapiens	9606		B cell adhesion adaptive immune response antigen processing and presentation carbohydrate binding cell surface cell-cell recognition cytoplasm endocytosis external side of plasma membrane extracellular region heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules host cell immune response innate immune response intracellular signal transduction intracellular transport of virus leukocyte cell-cell adhesion mannose binding membrane metal ion binding peptide antigen binding peptide antigen transport plasma membrane positive regulation of T cell proliferation positive regulation of viral life cycle regulation of T cell proliferation viral entry into host cell viral genome replication virion attachment to host cell virion binding virus receptor activity	GO:0001618 GO:0002250 GO:0005537 GO:0005576 GO:0005737 GO:0005886 GO:0006897 GO:0006955 GO:0007157 GO:0007159 GO:0009897 GO:0009986 GO:0009988 GO:0016020 GO:0019062 GO:0019079 GO:0019882 GO:0030246 GO:0035556 GO:0042102 GO:0042129 GO:0042605 GO:0043657 GO:0045087 GO:0046718 GO:0046790 GO:0046872 GO:0046968 GO:0075733 GO:0097323 GO:1903902
GL_000399	Fucolectin	AAA	AAA Fucolectin	Q7SIC1	1K12	LfDB0045	Fuc	Anguilla anguilla	7936		calcium ion binding carbohydrate binding extracellular region fucose binding regulation of cellular defense response regulation of complement activation, lectin pathway regulation of innate immune response	GO:0001868 GO:0005509 GO:0005576 GO:0010185 GO:0030246 GO:0042806 GO:0045088
GL_000001	16 kDa beta-galactoside-binding lectin	C16 CG-16	C16 CG-16 16 kDa beta-galactoside-binding lectin	P23668	1QMJ	LfDB0050	Gal	Gallus gallus	9031		carbohydrate binding extracellular space laminin binding	GO:0005615 GO:0030246 GO:0043236
GL_000489	Galectin-2	Galectin-2 (Rat)	Galectin-2 (Rat) Galectin-2	Q9Z144		LfDB0052		Rattus norvegicus	10116		T cell homeostasis carbohydrate binding cell-cell adhesion galactoside binding galectin complex positive regulation of apoptotic process positive regulation of inflammatory response	GO:0016936 GO:0030246 GO:0043029 GO:0043065 GO:0050729 GO:0098609 GO:1990724
GL_000487	Galectin-2	Galectin-2 (Human)	Galectin-2 (Human) Galectin-2	P05162	1HLC 5DG1 5DG2 5EWS	LfDB0055	Gal	Homo sapiens	9606	5110	T cell homeostasis carbohydrate binding cell-cell adhesion galactoside binding galectin complex positive regulation of apoptotic process positive regulation of inflammatory response	GO:0016936 GO:0030246 GO:0043029 GO:0043065 GO:0050729 GO:0098609 GO:1990724
GL_000491	Galectin-3	Gal3 Galectin-3 (Human)	Gal3 Galectin-3 (Human) Galectin-3	P17931	1A3K 1KJL 1KJR 2NMN 2NMO 2NN8 2XG3 3AYA 3AYC 3AYD 3AYE 3T1L 3T1M 3ZSJ 3ZSK 3ZSL 3ZSM 4BLI 4BLJ 4BM8 4JC1 4JCK 4LBJ 4LBK 4LBL 4LBM 4LBN 4LBO 4R9A 4R9B 4R9C 4R9D 4RL7 4XBN 5E88 5E89 5E8A 5EXO 5H9P 5H9R 5IUQ 5NF7 5NF9 5NFA 5NFB 5NFC 5OAX 5ODY 6B8K 6EOG 6EOL 6EXY 6EYM 6F2Q 6F6Y 6FK2 6FOF 6G0V 6H64 6I74 6I75 6I76 6I77 6I78 6KXA 6KXB 6Q0Q 6Q17 6QGE 6QGF 6QLN 6QLO 6QLP 6QLQ 6QLR 6QLS 6QLT 6QLU 6RHL 6RHM 6RZF 6RZG 6RZH 6RZI 6RZJ 6RZK 6RZL 6RZM 6TF6 6TF7 6Y4C 6Y78 6ZVF 7BE3 7CXA 7DF5 7RDO 7RDP 7RGX 7RGY 7RGZ 7RH0 7RH1 7RH3 7RH4 7XFA 7ZQX 8BZ3 8OJI 8OJK 8OJM 8OJO 8PPN	LfDB0056 LfDB0065	Gal	Homo sapiens	9606	103 104 106 107 108 115 116 5108	IgE binding RNA binding RNA splicing carbohydrate binding cell surface chemoattractant activity collagen-containing extracellular matrix cytoplasm cytosol eosinophil chemotaxis epithelial cell differentiation extracellular exosome extracellular region extracellular space ficolin-1-rich granule membrane immunological synapse innate immune response laminin binding mRNA processing macrophage chemotaxis membrane mitochondrial inner membrane molecular condensate scaffold activity monocyte chemotaxis mononuclear cell migration negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell negative regulation of T cell receptor signaling pathway negative regulation of endocytosis negative regulation of extrinsic apoptotic signaling pathway negative regulation of immunological synapse formation negative regulation of protein tyrosine phosphatase activity neutrophil chemotaxis nucleoplasm nucleus plasma membrane positive chemotaxis positive regulation of calcium ion import positive regulation of mononuclear cell migration positive regulation of protein localization to plasma membrane positive regulation of protein-containing complex assembly protein phosphatase binding protein phosphatase inhibitor activity regulation of T cell apoptotic process regulation of T cell proliferation regulation of extrinsic apoptotic signaling pathway via death domain receptors secretory granule membrane spliceosomal complex	GO:0001772 GO:0002548 GO:0003723 GO:0004864 GO:0005576 GO:0005615 GO:0005634 GO:0005654 GO:0005681 GO:0005737 GO:0005743 GO:0005829 GO:0005886 GO:0006397 GO:0008380 GO:0009986 GO:0016020 GO:0019863 GO:0019903 GO:0030246 GO:0030593 GO:0030667 GO:0030855 GO:0031334 GO:0042056 GO:0042129 GO:0043236 GO:0045087 GO:0045806 GO:0048245 GO:0048246 GO:0050860 GO:0050918 GO:0062023 GO:0070062 GO:0070232 GO:0071674 GO:0071677 GO:0090280 GO:0101003 GO:0140693 GO:1902041 GO:1903078 GO:1903614 GO:2000521 GO:2001189 GO:2001237
GL_000507	Galectin-7	Galectin-7 (Human)	Galectin-7 (Human) Galectin-7	P47929	1BKZ 2GAL 3GAL 3ZXE 3ZXF 4GAL 4UW3 4UW4 4UW5 4UW6 4XBQ 4Y26 5GAL 5H9Q 5H9S 6VTO 6VTP 6VTQ 6VTR 6VTS 7N4O 7N57 7N6C 7N8D 7N8G 7N96 7RDG 7TKW 7TKX 7TKY 7TKZ 7TRN 7TRO 7XAC 7XBL	LfDB0058	Gal	Homo sapiens	9606	1461 1702 1703 1710 5107	apoptotic process carbohydrate binding cytoplasm extracellular exosome extracellular space heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules nucleus	GO:0005615 GO:0005634 GO:0005737 GO:0006915 GO:0007157 GO:0030246 GO:0070062
GL_000096	Beta-galactoside-binding lectin	C14 CG-14	C14 CG-14 Beta-galactoside-binding lectin	P07583	3DUI	LfDB0063	Gal	Gallus gallus	9031		carbohydrate binding extracellular space laminin binding	GO:0005615 GO:0030246 GO:0043236
GL_001939	Agglutinin	HPA	HPA Agglutinin	Q2F1K8	2CCV 2CE6 2CGY 2CGZ	LfDB0105		Helix pomatia	6536	1356 1357 1358 1359 4881 4882	carbohydrate binding cell adhesion metal ion binding	GO:0007155 GO:0030246 GO:0046872
GL_002424	Alpha-L-arabinofuranosidase B	ABD	ABD Alpha-L-arabinofuranosidase B	Q8NK89	1WD3 1WD4 2D43 2D44 6SXR 6SXS 6SXT	LfDB0115	Others	Aspergillus luchuensis IFO 4308	1033177		L-arabinose metabolic process alpha-L-arabinofuranosidase activity arabinan catabolic process arabinose metabolic process extracellular region xylan catabolic process	GO:0005576 GO:0019566 GO:0031222 GO:0045493 GO:0046373 GO:0046556