GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Monosaccharide Specificities	Species	Taxonomy ID	GO Labels	GO IDs
GL_000684	Lectin	C0HJV2		Luffa acutangula	56866	carbohydrate binding	GO:0030246
GL_001149	Thiohydroximate-O-sulfate sulfur/sulfate-lyase (nitrile-forming) NSP3	O04318		Arabidopsis thaliana	3702	carbohydrate binding chloroplast cytosol glucosinolate catabolic process lyase activity metal ion binding nitrile biosynthetic process seed germination	GO:0005829 GO:0009507 GO:0009845 GO:0016829 GO:0019762 GO:0030246 GO:0046872 GO:0080028
GL_000874	Placental protein 13-like	Q8TCE9		Homo sapiens	9606	apoptotic process carbohydrate binding nucleoplasm	GO:0005654 GO:0006915 GO:0030246
GL_000992	Protein OS-9	Q5RKH6		Rattus norvegicus	10116	carbohydrate binding endoplasmic reticulum lumen endoplasmic reticulum unfolded protein response negative regulation of retrograde protein transport, ER to cytosol protease binding protein retention in ER lumen protein targeting protein ubiquitination response to endoplasmic reticulum stress retrograde protein transport, ER to cytosol ubiquitin-dependent ERAD pathway ubiquitin-dependent protein catabolic process	GO:0002020 GO:0005788 GO:0006511 GO:0006605 GO:0006621 GO:0016567 GO:0030246 GO:0030433 GO:0030968 GO:0030970 GO:0034976 GO:1904153
GL_001234	Alpha-mannosidase 2C1	Q91W89		Mus musculus	10090	alpha-mannosidase activity carbohydrate binding cytosol mannose metabolic process metal ion binding nucleoplasm oligosaccharide catabolic process	GO:0004559 GO:0005654 GO:0005829 GO:0006013 GO:0009313 GO:0030246 GO:0046872
GL_001410	Collagen alpha-1(IX) chain	P20849		Homo sapiens	9606	animal organ morphogenesis carbohydrate binding collagen type IX trimer collagen-containing extracellular matrix endoplasmic reticulum lumen extracellular matrix organization extracellular matrix structural constituent conferring tensile strength extracellular region extracellular space metal ion binding protein homodimerization activity	GO:0005576 GO:0005594 GO:0005615 GO:0005788 GO:0009887 GO:0030020 GO:0030198 GO:0030246 GO:0042803 GO:0046872 GO:0062023
GL_000313	Chitinase-3-like protein 1	Q9WTV1		Rattus norvegicus	10116	activation of NF-kappaB-inducing kinase activity apoptotic process carbohydrate binding carbohydrate metabolic process cellular response to interleukin-1 cellular response to tumor necrosis factor chitin binding chitin catabolic process cytoplasm endoplasmic reticulum extracellular region extracellular space inflammatory response lung development perinuclear region of cytoplasm positive regulation of ERK1 and ERK2 cascade positive regulation of angiogenesis positive regulation of interleukin-8 production positive regulation of peptidyl-threonine phosphorylation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction response to interleukin-1 response to interleukin-6 response to mechanical stimulus response to tumor necrosis factor	GO:0005576 GO:0005615 GO:0005737 GO:0005783 GO:0005975 GO:0006032 GO:0006915 GO:0006954 GO:0007250 GO:0008061 GO:0009612 GO:0010800 GO:0030246 GO:0030324 GO:0032757 GO:0034612 GO:0045766 GO:0048471 GO:0051897 GO:0070374 GO:0070555 GO:0070741 GO:0071347 GO:0071356
GL_002424	Alpha-L-arabinofuranosidase B	Q8NK89	Others	Aspergillus luchuensis IFO 4308	1033177	L-arabinose metabolic process alpha-L-arabinofuranosidase activity arabinan catabolic process arabinose metabolic process extracellular region xylan catabolic process	GO:0005576 GO:0019566 GO:0031222 GO:0045493 GO:0046373 GO:0046556
GL_000494	Galectin-3	P16110		Mus musculus	10090	Fc-gamma receptor I complex binding IgE binding RNA splicing advanced glycation end-product receptor activity antimicrobial humoral immune response mediated by antimicrobial peptide carbohydrate binding cell differentiation cell surface chemoattractant activity collagen-containing extracellular matrix cornified envelope cytoplasm cytosol disaccharide binding eosinophil chemotaxis external side of plasma membrane extracellular matrix extracellular matrix organization extracellular region extracellular space glial cell projection immunological synapse innate immune response killing of cells of another organism laminin binding mRNA processing macrophage chemotaxis mitochondrial inner membrane molecular condensate scaffold activity monocyte chemotaxis mononuclear cell migration monosaccharide binding negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell negative regulation of T cell receptor signaling pathway negative regulation of apoptotic process negative regulation of cell proliferation in bone marrow negative regulation of endocytosis negative regulation of extrinsic apoptotic signaling pathway negative regulation of immunological synapse formation neutrophil chemotaxis nucleoplasm nucleus oligosaccharide binding positive chemotaxis positive regulation of angiogenesis positive regulation of calcium ion import positive regulation of cell population proliferation positive regulation of mononuclear cell migration positive regulation of protein localization to plasma membrane positive regulation of protein-containing complex assembly positive regulation of serotonin secretion protein phosphatase binding regulation of T cell apoptotic process regulation of T cell proliferation regulation of extrinsic apoptotic signaling pathway via death domain receptors skeletal system development spliceosomal complex	GO:0001501 GO:0001533 GO:0001772 GO:0002548 GO:0005576 GO:0005615 GO:0005634 GO:0005654 GO:0005681 GO:0005737 GO:0005743 GO:0005829 GO:0006397 GO:0008284 GO:0008380 GO:0009897 GO:0009986 GO:0014064 GO:0019863 GO:0019903 GO:0030154 GO:0030198 GO:0030246 GO:0030593 GO:0031012 GO:0031334 GO:0031640 GO:0034988 GO:0042056 GO:0042129 GO:0043066 GO:0043236 GO:0045087 GO:0045766 GO:0045806 GO:0048029 GO:0048030 GO:0048245 GO:0048246 GO:0050785 GO:0050860 GO:0050918 GO:0061844 GO:0062023 GO:0070232 GO:0070492 GO:0071674 GO:0071677 GO:0090280 GO:0097386 GO:0140693 GO:1902041 GO:1903078 GO:1903769 GO:2000521 GO:2001189 GO:2001237
GL_001811	Putative glucose-6-phosphate 1-epimerase	P44160		Haemophilus influenzae Rd KW20	71421	carbohydrate binding carbohydrate metabolic process glucose-6-phosphate 1-epimerase activity	GO:0005975 GO:0030246 GO:0047938