GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID	GO Labels	GO IDs
GL_000006	Abrin-b	Q06077	Abrus precatorius	3816	carbohydrate binding defense response negative regulation of translation rRNA N-glycosylase activity toxin activity	GO:0006952 GO:0017148 GO:0030246 GO:0030598 GO:0090729
GL_000766	Low affinity immunoglobulin epsilon Fc receptor	P06734	Homo sapiens	9606	B cell antigen processing and presentation Fc receptor-mediated immune complex endocytosis IgE binding carbohydrate binding external side of plasma membrane extracellular exosome immune response integrin binding low-affinity IgE receptor activity macrophage activation metal ion binding plasma membrane positive regulation of humoral immune response mediated by circulating immunoglobulin positive regulation of killing of cells of another organism positive regulation of nitric-oxide synthase activity positive regulation of nitric-oxide synthase biosynthetic process	GO:0002450 GO:0002925 GO:0005178 GO:0005886 GO:0006955 GO:0009897 GO:0019769 GO:0019863 GO:0030246 GO:0042116 GO:0046872 GO:0051000 GO:0051712 GO:0051770 GO:0070062 GO:0160006
GL_001556	Glucans biosynthesis protein G	P67555	Escherichia coli CFT073	199310	carbohydrate binding catalytic activity glucan biosynthetic process periplasmic space	GO:0003824 GO:0009250 GO:0030246 GO:0042597
GL_001940	Mannan-binding lectin	Q2MDE2	Microcystis aeruginosa PCC 7806	267872	carbohydrate binding	GO:0030246
GL_000066	Arcelin-2	P19330	Phaseolus vulgaris	3885	carbohydrate binding defense response nutrient reservoir activity toxin activity	GO:0006952 GO:0030246 GO:0045735 GO:0090729
GL_001765	Probable rhamnogalacturonate lyase A	A2R2L1	Aspergillus niger CBS 513.88	425011	carbohydrate binding cell wall organization extracellular region polysaccharide catabolic process rhamnogalacturonan endolyase activity	GO:0000272 GO:0005576 GO:0030246 GO:0071555 GO:0102210
GL_001397	Chitinase A	P32823	Pseudoalteromonas piscicida	43662	calcium ion binding carbohydrate binding chitin binding chitin catabolic process chitinase activity extracellular region homophilic cell adhesion via plasma membrane adhesion molecules membrane polysaccharide catabolic process	GO:0000272 GO:0004568 GO:0005509 GO:0005576 GO:0006032 GO:0007156 GO:0008061 GO:0016020 GO:0030246
GL_001895	Zona pellucida sperm-binding protein 3	P42098	Sus scrofa	9823	acrosin binding binding of sperm to zona pellucida blastocyst formation carbohydrate binding collagen-containing extracellular matrix egg coat egg coat formation extracellular matrix extracellular space humoral immune response mediated by circulating immunoglobulin negative regulation of DNA-templated transcription negative regulation of binding of sperm to zona pellucida oocyte development plasma membrane positive regulation of DNA-templated transcription positive regulation of T cell proliferation positive regulation of acrosomal vesicle exocytosis positive regulation of acrosome reaction positive regulation of antral ovarian follicle growth positive regulation of humoral immune response positive regulation of inflammatory response positive regulation of interleukin-4 production positive regulation of leukocyte migration positive regulation of ovarian follicle development positive regulation of type II interferon production positive regulation of type IV hypersensitivity receptor ligand activity structural constituent of egg coat	GO:0001809 GO:0001825 GO:0002455 GO:0002687 GO:0002922 GO:0005615 GO:0005886 GO:0007339 GO:0030246 GO:0031012 GO:0032190 GO:0032729 GO:0032753 GO:0035803 GO:0035804 GO:0035805 GO:0042102 GO:0045892 GO:0045893 GO:0048018 GO:0048599 GO:0050729 GO:0062023 GO:2000344 GO:2000360 GO:2000368 GO:2000386 GO:2000388
GL_001708	Maltase-glucoamylase	O43451	Homo sapiens	9606	alpha-1,4-glucosidase activity amylase activity apical plasma membrane carbohydrate binding catalytic activity dextrin catabolic process extracellular exosome ficolin-1-rich granule membrane glucan 1,4-alpha-glucosidase activity maltose alpha-glucosidase activity maltose catabolic process plasma membrane starch catabolic process tertiary granule membrane	GO:0000025 GO:0003824 GO:0004339 GO:0004558 GO:0005886 GO:0005983 GO:0016160 GO:0016324 GO:0030246 GO:0032450 GO:0070062 GO:0070821 GO:0101003 GO:1901027
GL_002345	Outer capsid protein VP4	P12473	Simian rotavirus A strain RRV	444185	host cell endoplasmic reticulum-Golgi intermediate compartment host cell plasma membrane host cell rough endoplasmic reticulum host cytoskeleton membrane permeabilization of host organelle membrane involved in viral entry into host cell viral entry via permeabilization of inner membrane viral outer capsid virion attachment to host cell	GO:0016020 GO:0019062 GO:0020002 GO:0039624 GO:0039665 GO:0044163 GO:0044168 GO:0044172 GO:0099008