GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name ▲	UniProt ID	Species	Taxonomy ID	GO Labels	GO IDs
GL_001231	Alpha-mannosidase 2	Q16706	Homo sapiens	9606	Golgi medial cisterna Golgi membrane N-glycan processing alpha-mannosidase activity carbohydrate binding cis-Golgi network extracellular exosome hydrolase activity, hydrolyzing N-glycosyl compounds in utero embryonic development liver development lung alveolus development mannose metabolic process mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity membrane metal ion binding mitochondrion organization positive regulation of neurogenesis protein glycosylation protein homodimerization activity respiratory gaseous exchange by respiratory system retina morphogenesis in camera-type eye vacuole organization viral protein processing	GO:0000139 GO:0001701 GO:0001889 GO:0004559 GO:0004572 GO:0005797 GO:0005801 GO:0006013 GO:0006486 GO:0006491 GO:0007005 GO:0007033 GO:0007585 GO:0016020 GO:0016799 GO:0019082 GO:0030246 GO:0042803 GO:0046872 GO:0048286 GO:0050769 GO:0060042 GO:0070062
GL_001232	Alpha-mannosidase 2	P27046	Mus musculus	10090	Golgi apparatus Golgi medial cisterna Golgi membrane N-glycan processing alpha-mannosidase activity carbohydrate binding cis-Golgi network extracellular space hydrolase activity hydrolase activity, hydrolyzing N-glycosyl compounds identical protein binding in utero embryonic development liver development lung alveolus development mannose metabolic process mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity metal ion binding mitochondrion organization positive regulation of neurogenesis protein glycosylation protein homodimerization activity respiratory gaseous exchange by respiratory system retina morphogenesis in camera-type eye vacuole organization	GO:0000139 GO:0001701 GO:0001889 GO:0004559 GO:0004572 GO:0005615 GO:0005794 GO:0005797 GO:0005801 GO:0006013 GO:0006486 GO:0006491 GO:0007005 GO:0007033 GO:0007585 GO:0015923 GO:0016787 GO:0016799 GO:0030246 GO:0042802 GO:0042803 GO:0046872 GO:0048286 GO:0050769 GO:0060042
GL_001230	Alpha-mannosidase 2	P28494	Rattus norvegicus	10116	Golgi apparatus Golgi medial cisterna Golgi membrane N-glycan processing alpha-mannosidase activity carbohydrate binding cis-Golgi network extracellular space hydrolase activity hydrolase activity, hydrolyzing N-glycosyl compounds identical protein binding in utero embryonic development liver development lung alveolus development mannose metabolic process mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity mitochondrion organization positive regulation of neurogenesis protein glycosylation protein homodimerization activity respiratory gaseous exchange by respiratory system retina morphogenesis in camera-type eye vacuole organization zinc ion binding	GO:0000139 GO:0001701 GO:0001889 GO:0004559 GO:0004572 GO:0005615 GO:0005794 GO:0005797 GO:0005801 GO:0006013 GO:0006486 GO:0006491 GO:0007005 GO:0007033 GO:0007585 GO:0008270 GO:0015923 GO:0016787 GO:0016799 GO:0030246 GO:0042802 GO:0042803 GO:0048286 GO:0050769 GO:0060042
GL_001228	Alpha-mannosidase 2	Q24451	Drosophila melanogaster	7227	Golgi membrane Golgi stack N-glycan processing alpha-mannosidase activity carbohydrate binding encapsulation of foreign target endoplasmic reticulum mannose metabolic process mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity metal ion binding protein deglycosylation protein glycosylation rhodopsin biosynthetic process	GO:0000139 GO:0004559 GO:0004572 GO:0005783 GO:0005795 GO:0006013 GO:0006486 GO:0006491 GO:0006517 GO:0015923 GO:0016063 GO:0030246 GO:0035010 GO:0046872
GL_001229	Alpha-mannosidase 2	Q9LFR0	Arabidopsis thaliana	3702	Golgi apparatus Golgi cis cisterna Golgi membrane alpha-mannosidase activity carbohydrate binding endosome hyperosmotic salinity response mannose metabolic process mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity metal ion binding protein N-linked glycosylation trans-Golgi network	GO:0000137 GO:0000139 GO:0004559 GO:0004572 GO:0005768 GO:0005794 GO:0005802 GO:0006013 GO:0006487 GO:0030246 GO:0042538 GO:0046872
GL_001236	Alpha-mannosidase 2C1	P21139	Rattus norvegicus	10116	alpha-mannosidase activity carbohydrate binding cytosol mannose metabolic process metal ion binding oligosaccharide catabolic process	GO:0004559 GO:0005829 GO:0006013 GO:0009313 GO:0030246 GO:0046872
GL_001234	Alpha-mannosidase 2C1	Q91W89	Mus musculus	10090	alpha-mannosidase activity carbohydrate binding cytosol mannose metabolic process metal ion binding nucleoplasm oligosaccharide catabolic process	GO:0004559 GO:0005654 GO:0005829 GO:0006013 GO:0009313 GO:0030246 GO:0046872
GL_001235	Alpha-mannosidase 2C1	Q9NTJ4	Homo sapiens	9606	alpha-mannosidase activity carbohydrate binding cytosol mannose metabolic process metal ion binding nucleoplasm oligosaccharide catabolic process	GO:0004559 GO:0005654 GO:0005829 GO:0006013 GO:0009313 GO:0030246 GO:0046872
GL_001238	Alpha-mannosidase 2x	P49641	Homo sapiens	9606	Golgi membrane N-glycan processing alpha-mannosidase activity carbohydrate binding hydrolase activity, hydrolyzing N-glycosyl compounds mannose metabolic process mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity metal ion binding protein glycosylation	GO:0000139 GO:0004559 GO:0004572 GO:0006013 GO:0006486 GO:0006491 GO:0016799 GO:0030246 GO:0046872
GL_001237	Alpha-mannosidase 2x	Q8BRK9	Mus musculus	10090	Golgi membrane N-glycan processing alpha-mannosidase activity carbohydrate binding hydrolase activity, hydrolyzing N-glycosyl compounds mannose metabolic process mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity metal ion binding protein glycosylation	GO:0000139 GO:0004559 GO:0004572 GO:0006013 GO:0006486 GO:0006491 GO:0015923 GO:0016799 GO:0030246 GO:0046872