GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID	GO Labels ▲	GO IDs
GL_000816	NKG2-A/NKG2-B type II integral membrane protein	Q9MZJ3	Macaca mulatta	9544	CD8-positive, gamma-delta intraepithelial T cell differentiation HLA-E specific inhibitory MHC class Ib receptor activity adaptive immune response carbohydrate binding external side of plasma membrane innate immune response negative regulation of T cell mediated cytotoxicity negative regulation of natural killer cell mediated cytotoxicity plasma membrane positive regulation of natural killer cell mediated cytotoxicity stimulatory C-type lectin receptor signaling pathway transmembrane signaling receptor activity	GO:0001915 GO:0002223 GO:0002250 GO:0002305 GO:0004888 GO:0005886 GO:0009897 GO:0030246 GO:0045087 GO:0045953 GO:0045954 GO:0062082
GL_001384	CDP-diacylglycerol--inositol 3-phosphatidyltransferase	P70500	Rattus norvegicus	10116	CDP-diacylglycerol metabolic process CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity Golgi apparatus alcohol binding carbohydrate binding diacylglycerol binding endoplasmic reticulum membrane manganese ion binding membrane phosphatidylinositol biosynthetic process plasma membrane	GO:0003881 GO:0005789 GO:0005794 GO:0005886 GO:0006661 GO:0016020 GO:0019992 GO:0030145 GO:0030246 GO:0043178 GO:0046341
GL_001385	CDP-diacylglycerol--inositol 3-phosphatidyltransferase	Q8VDP6	Mus musculus	10090	CDP-diacylglycerol metabolic process CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity Golgi apparatus alcohol binding carbohydrate binding diacylglycerol binding endoplasmic reticulum membrane manganese ion binding membrane phosphatidylinositol biosynthetic process plasma membrane	GO:0003881 GO:0005789 GO:0005794 GO:0005886 GO:0006661 GO:0016020 GO:0019992 GO:0030145 GO:0030246 GO:0043178 GO:0046341
GL_002075	Vesicular integral-membrane protein VIP36	P49256	Canis lupus familiaris	9615	COPI-coated vesicle COPII-coated ER to Golgi transport vesicle Golgi apparatus Golgi membrane cell surface cytoplasmic vesicle endoplasmic reticulum membrane endoplasmic reticulum to Golgi vesicle-mediated transport endoplasmic reticulum-Golgi intermediate compartment exocytic vesicle extracellular space heat shock protein binding mannose binding metal ion binding perinuclear region of cytoplasm plasma membrane positive regulation of phagocytosis protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	GO:0000139 GO:0005537 GO:0005615 GO:0005789 GO:0005793 GO:0005794 GO:0005886 GO:0006888 GO:0006890 GO:0009986 GO:0015031 GO:0030134 GO:0030137 GO:0031072 GO:0031410 GO:0046872 GO:0048471 GO:0050766 GO:0070382
GL_002053	Protein ERGIC-53	P49257	Homo sapiens	9606	COPII-coated ER to Golgi transport vesicle ER to Golgi transport vesicle membrane Golgi membrane Golgi organization blood coagulation collagen-containing extracellular matrix endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum organization endoplasmic reticulum to Golgi vesicle-mediated transport endoplasmic reticulum-Golgi intermediate compartment endoplasmic reticulum-Golgi intermediate compartment membrane extracellular exosome mannose binding membrane metal ion binding negative regulation of protein targeting to mitochondrion positive regulation of organelle organization protein folding protein transport sarcomere unfolded protein binding	GO:0000139 GO:0005537 GO:0005783 GO:0005789 GO:0005793 GO:0006457 GO:0006888 GO:0007029 GO:0007030 GO:0007596 GO:0010638 GO:0012507 GO:0015031 GO:0016020 GO:0030017 GO:0030134 GO:0033116 GO:0046872 GO:0051082 GO:0062023 GO:0070062 GO:1903215
GL_002054	Protein ERGIC-53	Q62902	Rattus norvegicus	10116	COPII-coated ER to Golgi transport vesicle Golgi apparatus Golgi membrane Golgi organization calcium ion binding endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum organization endoplasmic reticulum to Golgi vesicle-mediated transport endoplasmic reticulum-Golgi intermediate compartment endoplasmic reticulum-Golgi intermediate compartment membrane identical protein binding mannose binding metal ion binding positive regulation of organelle organization protein transport sarcomere	GO:0000139 GO:0005509 GO:0005537 GO:0005783 GO:0005789 GO:0005793 GO:0005794 GO:0006888 GO:0007029 GO:0007030 GO:0010638 GO:0015031 GO:0030017 GO:0030134 GO:0033116 GO:0042802 GO:0046872
GL_002055	Protein ERGIC-53	Q9D0F3	Mus musculus	10090	COPII-coated ER to Golgi transport vesicle Golgi apparatus Golgi membrane Golgi organization collagen-containing extracellular matrix endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum organization endoplasmic reticulum to Golgi vesicle-mediated transport endoplasmic reticulum-Golgi intermediate compartment endoplasmic reticulum-Golgi intermediate compartment membrane identical protein binding mannose binding metal ion binding positive regulation of organelle organization protein transport sarcomere	GO:0000139 GO:0005537 GO:0005783 GO:0005789 GO:0005793 GO:0005794 GO:0006888 GO:0007029 GO:0007030 GO:0010638 GO:0015031 GO:0030017 GO:0030134 GO:0033116 GO:0042802 GO:0046872 GO:0062023
GL_001174	Vesicular integral-membrane protein VIP36	Q12907	Homo sapiens	9606	COPII-coated ER to Golgi transport vesicle Golgi apparatus Golgi membrane carbohydrate binding cell surface endoplasmic reticulum membrane endoplasmic reticulum to Golgi vesicle-mediated transport endoplasmic reticulum-Golgi intermediate compartment endoplasmic reticulum-Golgi intermediate compartment membrane extracellular exosome extracellular space heat shock protein binding mannose binding metal ion binding plasma membrane positive regulation of phagocytosis protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	GO:0000139 GO:0005537 GO:0005615 GO:0005789 GO:0005793 GO:0005794 GO:0005886 GO:0006888 GO:0006890 GO:0009986 GO:0015031 GO:0030134 GO:0030246 GO:0031072 GO:0033116 GO:0046872 GO:0050766 GO:0070062
GL_001175	Vesicular integral-membrane protein VIP36	Q9DBH5	Mus musculus	10090	COPII-coated ER to Golgi transport vesicle Golgi apparatus Golgi membrane carbohydrate binding cell surface endoplasmic reticulum membrane endoplasmic reticulum to Golgi vesicle-mediated transport endoplasmic reticulum-Golgi intermediate compartment extracellular space heat shock protein binding mannose binding metal ion binding plasma membrane positive regulation of phagocytosis protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	GO:0000139 GO:0005537 GO:0005615 GO:0005789 GO:0005793 GO:0005794 GO:0005886 GO:0006888 GO:0006890 GO:0009986 GO:0015031 GO:0030134 GO:0030246 GO:0031072 GO:0046872 GO:0050766
GL_001677	L-type lectin-like domain-containing protein C4F6.05c	O42707	Schizosaccharomyces pombe 972h-	284812	COPII-coated ER to Golgi transport vesicle Golgi apparatus Golgi membrane carbohydrate binding endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum to Golgi vesicle-mediated transport endoplasmic reticulum-Golgi intermediate compartment intracellular protein transport mannose binding	GO:0000139 GO:0005537 GO:0005783 GO:0005789 GO:0005793 GO:0005794 GO:0006886 GO:0006888 GO:0030134 GO:0030246