GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID	GO Labels ▲	GO IDs
GL_001192	6-phosphogluconate dehydrogenase, decarboxylating	P85968	Rattus norvegicus	10116	D-gluconate catabolic process D-gluconate metabolic process NADP binding NADP metabolic process carbohydrate binding carboxylic acid binding cytosol pentose biosynthetic process pentose-phosphate shunt pentose-phosphate shunt, oxidative branch phosphogluconate dehydrogenase (decarboxylating) activity	GO:0004616 GO:0005829 GO:0006098 GO:0006739 GO:0009051 GO:0019322 GO:0019521 GO:0030246 GO:0031406 GO:0046177 GO:0050661
GL_001821	Ribose-5-phosphate isomerase	P47968	Mus musculus	10090	D-ribose metabolic process carbohydrate binding cytosol identical protein binding monosaccharide binding pentose-phosphate shunt pentose-phosphate shunt, non-oxidative branch ribose-5-phosphate isomerase activity	GO:0004751 GO:0005829 GO:0006014 GO:0006098 GO:0009052 GO:0030246 GO:0042802 GO:0048029
GL_001827	Ribulose-phosphate 3-epimerase	Q8VEE0	Mus musculus	10090	D-ribulose-phosphate 3-epimerase activity carbohydrate binding carbohydrate metabolic process cytosol identical protein binding metal ion binding monosaccharide binding pentose-phosphate shunt pentose-phosphate shunt, non-oxidative branch protein homodimerization activity	GO:0004750 GO:0005829 GO:0005975 GO:0006098 GO:0009052 GO:0030246 GO:0042802 GO:0042803 GO:0046872 GO:0048029
GL_001431	D-xylose-binding periplasmic protein	P45047	Haemophilus influenzae Rd KW20	71421	D-xylose transmembrane transport carbohydrate binding monosaccharide binding outer membrane-bounded periplasmic space	GO:0015753 GO:0030246 GO:0030288 GO:0048029
GL_000272	Calreticulin	P27797	Homo sapiens	9606	DNA binding MHC class I peptide loading complex RNA binding acrosomal vesicle calcium ion binding carbohydrate binding cardiac muscle cell differentiation cell surface cellular response to electrical stimulus cellular response to lithium ion cellular response to virus cellular senescence collagen-containing extracellular matrix complement component C1q complex binding cortical actin cytoskeleton organization cortical granule cytolytic granule cytoplasm cytosol endocytic vesicle lumen endoplasmic reticulum endoplasmic reticulum lumen endoplasmic reticulum membrane endoplasmic reticulum quality control compartment endoplasmic reticulum-Golgi intermediate compartment membrane external side of plasma membrane extracellular exosome extracellular region extracellular space focal adhesion glucocorticoid receptor signaling pathway hormone binding integrin binding intracellular calcium ion homeostasis iron ion binding lumenal side of endoplasmic reticulum membrane mRNA binding membrane negative regulation of DNA-templated transcription negative regulation of intracellular steroid hormone receptor signaling pathway negative regulation of neuron differentiation negative regulation of retinoic acid receptor signaling pathway negative regulation of transcription by RNA polymerase II negative regulation of translation negative regulation of trophoblast cell migration nuclear androgen receptor binding nuclear envelope nuclear export signal receptor activity nucleus obsolete selective autophagy peptide antigen assembly with MHC class I protein complex peptide binding perinuclear region of cytoplasm phagocytic vesicle membrane polysome positive regulation of cell cycle positive regulation of cell population proliferation positive regulation of dendritic cell chemotaxis positive regulation of endothelial cell migration positive regulation of gene expression positive regulation of non-canonical NF-kappaB signal transduction positive regulation of phagocytosis positive regulation of substrate adhesion-dependent cell spreading protein export from nucleus protein folding protein folding chaperone protein folding in endoplasmic reticulum protein localization to nucleus protein maturation by protein folding protein stabilization protein-folding chaperone binding regulation of DNA-templated transcription regulation of apoptotic process regulation of meiotic nuclear division response to estradiol response to glycoside response to testosterone response to xenobiotic stimulus sarcoplasmic reticulum lumen sequestering of calcium ion smooth endoplasmic reticulum spermatogenesis ubiquitin protein ligase binding ubiquitin-dependent ERAD pathway unfolded protein binding zinc ion binding	GO:0000122 GO:0001669 GO:0001849 GO:0002502 GO:0003677 GO:0003723 GO:0003729 GO:0005049 GO:0005178 GO:0005506 GO:0005509 GO:0005576 GO:0005615 GO:0005634 GO:0005635 GO:0005737 GO:0005783 GO:0005788 GO:0005789 GO:0005790 GO:0005829 GO:0005844 GO:0005925 GO:0006355 GO:0006457 GO:0006611 GO:0006874 GO:0007283 GO:0008270 GO:0008284 GO:0009410 GO:0009897 GO:0009986 GO:0010595 GO:0010628 GO:0016020 GO:0017148 GO:0022417 GO:0030246 GO:0030433 GO:0030670 GO:0030866 GO:0031625 GO:0032355 GO:0033018 GO:0033116 GO:0033144 GO:0033574 GO:0034504 GO:0034975 GO:0040020 GO:0042277 GO:0042562 GO:0042824 GO:0042921 GO:0042981 GO:0044183 GO:0044194 GO:0044322 GO:0045665 GO:0045787 GO:0045892 GO:0048387 GO:0048471 GO:0050681 GO:0050766 GO:0050821 GO:0051082 GO:0051087 GO:0051208 GO:0055007 GO:0060473 GO:0061912 GO:0062023 GO:0070062 GO:0071257 GO:0071285 GO:0071682 GO:0090398 GO:0098553 GO:0098586 GO:1900026 GO:1901164 GO:1901224 GO:1903416 GO:2000510
GL_002404	Collectin-11	Q9BWP8	Homo sapiens	9606	DNA binding antimicrobial humoral response calcium ion binding calcium-dependent carbohydrate binding cell surface pattern recognition receptor signaling pathway collagen trimer complement activation complement activation, lectin pathway developmental process execution phase of apoptosis external side of plasma membrane extracellular region extracellular space fucose binding identical protein binding mannose binding oligosaccharide binding positive regulation of opsonization proteolysis serine-type endopeptidase complex	GO:0001867 GO:0002752 GO:0003677 GO:0005509 GO:0005537 GO:0005576 GO:0005581 GO:0005615 GO:0006508 GO:0006956 GO:0009897 GO:0019730 GO:0032502 GO:0042802 GO:0042806 GO:0070492 GO:0097194 GO:0120153 GO:1903028 GO:1905370
GL_001862	Transcriptional regulator LsrR	Q7N2E0	Photorhabdus laumondii subsp. laumondii TTO1	243265	DNA binding carbohydrate binding cytoplasm regulation of DNA-templated transcription	GO:0003677 GO:0005737 GO:0006355 GO:0030246
GL_001854	Transcriptional regulator LsrR	A6TEB9	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	272620	DNA binding carbohydrate binding cytoplasm	GO:0003677 GO:0005737 GO:0030246
GL_001860	Transcriptional regulator LsrR	B1LFA3	Escherichia coli SMS-3-5	439855	DNA binding carbohydrate binding cytoplasm	GO:0003677 GO:0005737 GO:0030246
GL_001853	Transcriptional regulator LsrR	Q8XAY6	Escherichia coli O157:H7	83334	DNA binding carbohydrate binding cytoplasm	GO:0003677 GO:0005737 GO:0030246