GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin ▲	Lectin Name	UniProt ID	Species	Taxonomy ID	GO Labels	GO IDs
GL_000181	C-type lectin domain family 4 member E	Q67EQ1	Rattus norvegicus	10116	Fc-gamma receptor signaling pathway T cell differentiation involved in immune response antifungal innate immune response calcium ion binding carbohydrate binding cell projection defense response to bacterium external side of plasma membrane glycolipid binding immune response innate immune response membrane pattern recognition receptor activity pattern recognition receptor signaling pathway phagocytic cup phagocytic vesicle membrane plasma membrane positive regulation of cytokine production signaling receptor activity	GO:0001819 GO:0001891 GO:0002221 GO:0002292 GO:0005509 GO:0005886 GO:0006955 GO:0009897 GO:0016020 GO:0030246 GO:0030670 GO:0038023 GO:0038094 GO:0038187 GO:0042742 GO:0042995 GO:0045087 GO:0051861 GO:0061760
GL_000182	C-type lectin domain family 4 member E	Q9R0Q8	Mus musculus	10090	Fc-gamma receptor signaling pathway T cell differentiation involved in immune response antifungal innate immune response calcium ion binding carbohydrate binding cell projection defense response to bacterium external side of plasma membrane glycolipid binding immune response innate immune response membrane pattern recognition receptor activity pattern recognition receptor signaling pathway phagocytic cup phagocytic vesicle membrane plasma membrane positive regulation of cytokine production signaling receptor activity	GO:0001819 GO:0001891 GO:0002221 GO:0002292 GO:0005509 GO:0005886 GO:0006955 GO:0009897 GO:0016020 GO:0030246 GO:0030670 GO:0038023 GO:0038094 GO:0038187 GO:0042742 GO:0042995 GO:0045087 GO:0051861 GO:0061760
GL_000183	C-type lectin domain family 4 member F	P10716	Rattus norvegicus	10116	NK T cell activation carbohydrate binding endocytosis external side of plasma membrane galactose binding glycolipid binding plasma membrane positive regulation of gene expression	GO:0005534 GO:0005886 GO:0006897 GO:0009897 GO:0010628 GO:0030246 GO:0051132 GO:0051861
GL_000184	C-type lectin domain family 4 member F	P70194	Mus musculus	10090	NK T cell activation carbohydrate binding endocytosis external side of plasma membrane galactose binding glycolipid binding plasma membrane	GO:0005534 GO:0005886 GO:0006897 GO:0009897 GO:0030246 GO:0051132 GO:0051861
GL_000185	C-type lectin domain family 4 member F	Q8N1N0	Homo sapiens	9606	carbohydrate binding endocytosis external side of plasma membrane	GO:0006897 GO:0009897 GO:0030246
GL_000186	C-type lectin domain family 4 member G	Q8BNX1	Mus musculus	10090	T cell mediated immunity alpha-beta T cell proliferation carbohydrate binding carbohydrate derivative binding external side of plasma membrane fructose binding immature T cell proliferation in thymus immune response mannose binding negative regulation of T cell mediated immunity negative regulation of T cell proliferation negative regulation of alpha-beta T cell proliferation negative regulation of immature T cell proliferation in thymus plasma membrane polysaccharide binding positive regulation of viral life cycle viral entry into host cell virus coreceptor activity virus receptor activity	GO:0001618 GO:0002456 GO:0002710 GO:0005537 GO:0005886 GO:0006955 GO:0009897 GO:0030246 GO:0030247 GO:0033080 GO:0033088 GO:0042130 GO:0046633 GO:0046642 GO:0046718 GO:0070061 GO:0097367 GO:0120274 GO:1903902
GL_000187	C-type lectin domain family 4 member G	Q6UXB4	Homo sapiens	9606	T cell mediated immunity alpha-beta T cell proliferation carbohydrate binding carbohydrate derivative binding external side of plasma membrane fructose binding glycosylated region protein binding immature T cell proliferation in thymus immune response mannose binding negative regulation of T cell mediated immunity negative regulation of alpha-beta T cell proliferation negative regulation of immature T cell proliferation in thymus plasma membrane polysaccharide binding positive regulation of viral life cycle viral entry into host cell virus coreceptor activity virus receptor activity	GO:0001618 GO:0002456 GO:0002710 GO:0005537 GO:0005886 GO:0006955 GO:0009897 GO:0030246 GO:0030247 GO:0033080 GO:0033088 GO:0046633 GO:0046642 GO:0046718 GO:0070061 GO:0097367 GO:0120274 GO:0140081 GO:1903902
GL_000188	C-type lectin domain family 4 member K	Q8VBX4	Mus musculus	10090	carbohydrate binding defense response to virus external side of plasma membrane plasma membrane	GO:0005886 GO:0009897 GO:0030246 GO:0051607
GL_000189	C-type lectin domain family 4 member K	Q9UJ71	Homo sapiens	9606	carbohydrate binding clathrin-coated endocytic vesicle membrane defense response to virus early endosome membrane endocytic vesicle external side of plasma membrane mannose binding plasma membrane	GO:0005537 GO:0005886 GO:0009897 GO:0030139 GO:0030246 GO:0030669 GO:0031901 GO:0051607
GL_000190	C-type lectin domain family 5 member A	Q9NY25	Homo sapiens	9606	carbohydrate binding cell surface cellular defense response cytosol innate immune response myeloid cell differentiation negative regulation of apoptotic process negative regulation of myeloid cell apoptotic process osteoblast development plasma membrane positive regulation of cytokine production signal transduction specific granule membrane tertiary granule membrane virus receptor activity	GO:0001618 GO:0001819 GO:0002076 GO:0005829 GO:0005886 GO:0006968 GO:0007165 GO:0009986 GO:0030099 GO:0030246 GO:0033033 GO:0035579 GO:0043066 GO:0045087 GO:0070821