GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species ▲	Taxonomy ID	GO Labels	GO IDs
GL_001782	Protein AMBP	Q64240	Rattus norvegicus	10116	IgA binding carbohydrate binding cell surface cytosol endoplasmic reticulum extracellular space heme binding mitochondrial inner membrane nuclear membrane oxidoreductase activity plasma membrane protein catabolic process protein homodimerization activity serine-type endopeptidase inhibitor activity	GO:0004867 GO:0005615 GO:0005743 GO:0005783 GO:0005829 GO:0005886 GO:0009986 GO:0016491 GO:0019862 GO:0020037 GO:0030163 GO:0030246 GO:0031965 GO:0042803
GL_000240	C-type mannose receptor 2	Q4TU93	Rattus norvegicus	10116	carbohydrate binding collagen binding collagen catabolic process endocytosis plasma membrane signaling receptor activity	GO:0005518 GO:0005886 GO:0006897 GO:0030246 GO:0030574 GO:0038023
GL_001989	C-type lectin domain family 10 member A	P49301	Rattus norvegicus	10116	connective tissue replacement involved in inflammatory response wound healing external side of plasma membrane fucose binding mannose binding	GO:0002248 GO:0005537 GO:0009897 GO:0042806
GL_001694	Lysosomal alpha-glucosidase	Q6P7A9	Rattus norvegicus	10116	alpha-1,4-glucosidase activity alpha-glucosidase activity aorta development autolysosome lumen carbohydrate binding cardiac muscle contraction diaphragm contraction glycogen catabolic process glycogen metabolic process glycophagy heart morphogenesis locomotory behavior lysosomal membrane lysosome lysosome organization maltose alpha-glucosidase activity membrane muscle cell cellular homeostasis neuromuscular process controlling balance neuromuscular process controlling posture regulation of the force of heart contraction striated muscle contraction tissue development vacuolar sequestering	GO:0002026 GO:0002086 GO:0003007 GO:0004558 GO:0005764 GO:0005765 GO:0005977 GO:0005980 GO:0006941 GO:0007040 GO:0007626 GO:0009888 GO:0016020 GO:0030246 GO:0032450 GO:0035904 GO:0043181 GO:0046716 GO:0050884 GO:0050885 GO:0060048 GO:0061723 GO:0090599 GO:0120282
GL_001013	Pulmonary surfactant-associated protein A	P08427	Rattus norvegicus	10116	carbohydrate binding cellular response to mechanical stimulus cellular response to nitric oxide circadian rhythm collagen trimer extracellular space metal ion binding multivesicular body opsonization positive regulation of phagocytosis respiratory gaseous exchange by respiratory system response to epidermal growth factor response to glucocorticoid response to hormone response to hyperoxia response to hypoxia response to interleukin-6 response to lipopolysaccharide response to retinoic acid response to vitamin A	GO:0001666 GO:0005581 GO:0005615 GO:0005771 GO:0007585 GO:0007623 GO:0008228 GO:0009725 GO:0030246 GO:0032496 GO:0032526 GO:0033189 GO:0046872 GO:0050766 GO:0051384 GO:0055093 GO:0070741 GO:0070849 GO:0071260 GO:0071732
GL_000168	C-type lectin domain family 2 member L	Q0ZCA7	Rattus norvegicus	10116	carbohydrate binding membrane	GO:0016020 GO:0030246
GL_000506	Galectin-7	P97590	Rattus norvegicus	10116	apoptotic process carbohydrate binding cornified envelope cytoplasm extracellular region nucleus	GO:0001533 GO:0005576 GO:0005634 GO:0005737 GO:0006915 GO:0030246
GL_000536	Grifin	O88644	Rattus norvegicus	10116	carbohydrate binding	GO:0030246
GL_001667	Interleukin-2	P17108	Rattus norvegicus	10116	G protein-coupled receptor signaling pathway T cell proliferation activated T cell proliferation adaptive immune response carbohydrate binding cytokine activity extracellular space extrinsic apoptotic signaling pathway in absence of ligand gene expression glycosphingolipid binding growth factor activity interleukin-2 receptor binding interleukin-2-mediated signaling pathway kappa-type opioid receptor binding leukocyte activation involved in immune response lymphocyte proliferation negative regulation of B cell apoptotic process negative regulation of T-helper 17 cell differentiation negative regulation of inflammatory response negative regulation of lymphocyte proliferation negative regulation of protein phosphorylation positive regulation of B cell proliferation positive regulation of T cell differentiation positive regulation of T cell proliferation positive regulation of activated T cell proliferation positive regulation of cytosolic calcium ion concentration positive regulation of dendritic spine development positive regulation of immunoglobulin production positive regulation of interleukin-17 production positive regulation of isotype switching to IgG isotypes positive regulation of plasma cell differentiation positive regulation of protein phosphorylation positive regulation of regulatory T cell differentiation positive regulation of transcription by RNA polymerase II positive regulation of type II interferon production positive regulation of tyrosine phosphorylation of STAT protein protein kinase C-activating G protein-coupled receptor signaling pathway regulation of CD4-positive, alpha-beta T cell proliferation regulation of T cell homeostatic proliferation response to ethanol response to tacrolimus transcription by RNA polymerase II	GO:0001933 GO:0001934 GO:0002250 GO:0002366 GO:0002639 GO:0002903 GO:0005125 GO:0005134 GO:0005615 GO:0006366 GO:0007186 GO:0007204 GO:0007205 GO:0008083 GO:0010467 GO:0030246 GO:0030890 GO:0031851 GO:0032729 GO:0032740 GO:0038110 GO:0042098 GO:0042102 GO:0042104 GO:0042531 GO:0043208 GO:0045471 GO:0045582 GO:0045591 GO:0045944 GO:0046013 GO:0046651 GO:0048304 GO:0050672 GO:0050728 GO:0050798 GO:0060999 GO:0097192 GO:1900100 GO:1901327 GO:2000320 GO:2000561
GL_000813	Neuronal pentraxin-2	P97738	Rattus norvegicus	10116	associative learning carbohydrate binding extrinsic component of postsynaptic specialization membrane glutamatergic synapse metal ion binding neurotransmitter receptor localization to postsynaptic specialization membrane synaptic cleft	GO:0008306 GO:0030246 GO:0043083 GO:0046872 GO:0098892 GO:0098978 GO:0099645