GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name ▼	UniProt ID	Species	Taxonomy ID	GO Labels	GO IDs
GL_000185	C-type lectin domain family 4 member F	Q8N1N0	Homo sapiens	9606	carbohydrate binding endocytosis external side of plasma membrane	GO:0006897 GO:0009897 GO:0030246
GL_000182	C-type lectin domain family 4 member E	Q9R0Q8	Mus musculus	10090	Fc-gamma receptor signaling pathway T cell differentiation involved in immune response antifungal innate immune response calcium ion binding carbohydrate binding cell projection defense response to bacterium external side of plasma membrane glycolipid binding immune response innate immune response membrane pattern recognition receptor activity pattern recognition receptor signaling pathway phagocytic cup phagocytic vesicle membrane plasma membrane positive regulation of cytokine production signaling receptor activity	GO:0001819 GO:0001891 GO:0002221 GO:0002292 GO:0005509 GO:0005886 GO:0006955 GO:0009897 GO:0016020 GO:0030246 GO:0030670 GO:0038023 GO:0038094 GO:0038187 GO:0042742 GO:0042995 GO:0045087 GO:0051861 GO:0061760
GL_000180	C-type lectin domain family 4 member E	Q9ULY5	Homo sapiens	9606	Fc-gamma receptor signaling pathway T cell differentiation involved in immune response antifungal innate immune response calcium ion binding carbohydrate binding cell projection defense response to bacterium external side of plasma membrane glycolipid binding innate immune response membrane pattern recognition receptor activity pattern recognition receptor signaling pathway phagocytic cup phagocytic vesicle membrane plasma membrane positive regulation of cytokine production	GO:0001819 GO:0001891 GO:0002221 GO:0002292 GO:0005509 GO:0005886 GO:0009897 GO:0016020 GO:0030246 GO:0030670 GO:0038094 GO:0038187 GO:0042742 GO:0042995 GO:0045087 GO:0051861 GO:0061760
GL_001925	C-type lectin domain family 4 member E	E1BHM0	Bos taurus	9913	Fc-gamma receptor signaling pathway T cell differentiation involved in immune response antifungal innate immune response calcium ion binding carbohydrate binding defense response to bacterium external side of plasma membrane glycolipid binding pattern recognition receptor activity pattern recognition receptor signaling pathway phagocytic vesicle membrane positive regulation of cytokine production	GO:0001819 GO:0002221 GO:0002292 GO:0005509 GO:0009897 GO:0030246 GO:0030670 GO:0038094 GO:0038187 GO:0042742 GO:0051861 GO:0061760
GL_000181	C-type lectin domain family 4 member E	Q67EQ1	Rattus norvegicus	10116	Fc-gamma receptor signaling pathway T cell differentiation involved in immune response antifungal innate immune response calcium ion binding carbohydrate binding cell projection defense response to bacterium external side of plasma membrane glycolipid binding immune response innate immune response membrane pattern recognition receptor activity pattern recognition receptor signaling pathway phagocytic cup phagocytic vesicle membrane plasma membrane positive regulation of cytokine production signaling receptor activity	GO:0001819 GO:0001891 GO:0002221 GO:0002292 GO:0005509 GO:0005886 GO:0006955 GO:0009897 GO:0016020 GO:0030246 GO:0030670 GO:0038023 GO:0038094 GO:0038187 GO:0042742 GO:0042995 GO:0045087 GO:0051861 GO:0061760
GL_000178	C-type lectin domain family 4 member D	Q8WXI8	Homo sapiens	9606	Fc-gamma receptor signaling pathway T cell differentiation involved in immune response adaptive immune response antifungal innate immune response carbohydrate binding defense response to bacterium external side of plasma membrane ficolin-1-rich granule membrane immunoglobulin receptor binding mannose binding metal ion binding pattern recognition receptor activity plasma membrane positive regulation of canonical NF-kappaB signal transduction positive regulation of myeloid dendritic cell activation specific granule membrane tertiary granule membrane	GO:0002250 GO:0002292 GO:0005537 GO:0005886 GO:0009897 GO:0030246 GO:0030887 GO:0034987 GO:0035579 GO:0038094 GO:0038187 GO:0042742 GO:0043123 GO:0046872 GO:0061760 GO:0070821 GO:0101003
GL_000177	C-type lectin domain family 4 member D	Q9Z2H6	Mus musculus	10090	Fc-gamma receptor signaling pathway T cell differentiation involved in immune response adaptive immune response antifungal innate immune response carbohydrate binding defense response to bacterium external side of plasma membrane immunoglobulin receptor binding innate immune response mannose binding metal ion binding pattern recognition receptor activity plasma membrane positive regulation of canonical NF-kappaB signal transduction positive regulation of myeloid dendritic cell activation	GO:0002250 GO:0002292 GO:0005537 GO:0005886 GO:0009897 GO:0030246 GO:0030887 GO:0034987 GO:0038094 GO:0038187 GO:0042742 GO:0043123 GO:0045087 GO:0046872 GO:0061760
GL_000179	C-type lectin domain family 4 member D	Q69FH1	Rattus norvegicus	10116	Fc-gamma receptor signaling pathway T cell differentiation involved in immune response adaptive immune response antifungal innate immune response carbohydrate binding defense response to bacterium external side of plasma membrane immunoglobulin receptor binding innate immune response mannose binding metal ion binding pattern recognition receptor activity plasma membrane positive regulation of canonical NF-kappaB signal transduction positive regulation of myeloid dendritic cell activation	GO:0002250 GO:0002292 GO:0005537 GO:0005886 GO:0009897 GO:0030246 GO:0030887 GO:0034987 GO:0038094 GO:0038187 GO:0042742 GO:0043123 GO:0045087 GO:0046872 GO:0061760
GL_000176	C-type lectin domain family 4 member C	Q8WTT0	Homo sapiens	9606	adaptive immune response antifungal innate immune response carbohydrate binding external side of plasma membrane ficolin-1-rich granule membrane metal ion binding plasma membrane secretory granule membrane tertiary granule membrane	GO:0002250 GO:0005886 GO:0009897 GO:0030246 GO:0030667 GO:0046872 GO:0061760 GO:0070821 GO:0101003
GL_000174	C-type lectin domain family 4 member A	Q9UMR7	Homo sapiens	9606	CD8-positive, alpha-beta T cell activation adaptive immune response antifungal innate immune response antigen processing and presentation of exogenous peptide antigen via MHC class I calcium ion binding carbohydrate binding cell adhesion cell surface receptor signaling pathway external side of plasma membrane mannose binding negative regulation of cytokine production negative regulation of tumor necrosis factor production plasma membrane plasmacytoid dendritic cell antigen processing and presentation transmembrane signaling receptor activity	GO:0001818 GO:0002250 GO:0002470 GO:0004888 GO:0005509 GO:0005537 GO:0005886 GO:0007155 GO:0007166 GO:0009897 GO:0030246 GO:0032720 GO:0036037 GO:0042590 GO:0061760