GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database Last Updated
MCAW-DB July 10, 2019
UniLectin June 14, 2023
UniProt February 16, 2024
Lectin Frontier DataBase (LfDB) February 16, 2024
CarboGrove June 14, 2023
GlyCosmos Lectin Lectin Name UniProt ID Monosaccharide Specificities Species Taxonomy ID ▲ GO Labels GO IDs
Cell surface hyaluronidase
10090
  • angiogenesis
  • calcium ion binding
  • carbohydrate binding
  • cytosol
  • hyaluronan catabolic process
  • hyalurononglucosaminidase activity
  • intracellular membrane-bounded organelle
  • nucleolus
  • plasma membrane
  • regulation of sprouting angiogenesis
  • GO:0001525
  • GO:0004415
  • GO:0005509
  • GO:0005730
  • GO:0005829
  • GO:0005886
  • GO:0030214
  • GO:0030246
  • GO:0043231
  • GO:1903670
C-type lectin domain family 4 member K
10090
  • carbohydrate binding
  • defense response to virus
  • external side of plasma membrane
  • plasma membrane
  • GO:0005886
  • GO:0009897
  • GO:0030246
  • GO:0051607
F-box only protein 6
10090
  • DNA repair
  • SCF ubiquitin ligase complex
  • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
  • carbohydrate binding
  • cytoplasm
  • endoplasmic reticulum quality control compartment
  • glycoprotein catabolic process
  • protein ubiquitination
  • response to unfolded protein
  • ubiquitin-dependent ERAD pathway
  • ubiquitin-dependent glycoprotein ERAD pathway
  • GO:0005737
  • GO:0006281
  • GO:0006516
  • GO:0006986
  • GO:0016567
  • GO:0019005
  • GO:0030246
  • GO:0030433
  • GO:0031146
  • GO:0044322
  • GO:0097466
Protein OS-9
10090
  • carbohydrate binding
  • endoplasmic reticulum
  • endoplasmic reticulum lumen
  • endoplasmic reticulum unfolded protein response
  • negative regulation of retrograde protein transport, ER to cytosol
  • protease binding
  • protein retention in ER lumen
  • protein targeting
  • protein ubiquitination
  • response to endoplasmic reticulum stress
  • retrograde protein transport, ER to cytosol
  • ubiquitin-dependent ERAD pathway
  • ubiquitin-dependent protein catabolic process
  • GO:0002020
  • GO:0005783
  • GO:0005788
  • GO:0006511
  • GO:0006605
  • GO:0006621
  • GO:0016567
  • GO:0030246
  • GO:0030433
  • GO:0030968
  • GO:0030970
  • GO:0034976
  • GO:1904153
CD209 antigen-like protein E
10090
  • B cell adhesion
  • endocytosis
  • external side of plasma membrane
  • immune response
  • mannose binding
  • membrane
  • plasma membrane
  • positive regulation of T cell proliferation
  • positive regulation of viral life cycle
  • viral entry into host cell
  • virus receptor activity
  • GO:0001618
  • GO:0005537
  • GO:0005886
  • GO:0006897
  • GO:0006955
  • GO:0009897
  • GO:0016020
  • GO:0042102
  • GO:0046718
  • GO:0097323
  • GO:1903902
Protein FAM3A
10090
  • antifungal humoral response
  • antimicrobial humoral immune response mediated by antimicrobial peptide
  • carbohydrate binding
  • extracellular space
  • negative regulation of antifungal innate immune response
  • GO:0005615
  • GO:0019732
  • GO:0030246
  • GO:0061844
  • GO:1905035
C-type lectin domain family 5 member A
10090
  • carbohydrate binding
  • cell surface
  • cytosol
  • innate immune response
  • myeloid cell differentiation
  • negative regulation of apoptotic process
  • negative regulation of myeloid cell apoptotic process
  • osteoblast development
  • plasma membrane
  • positive regulation of cytokine production
  • virus receptor activity
  • GO:0001618
  • GO:0001819
  • GO:0002076
  • GO:0005829
  • GO:0005886
  • GO:0009986
  • GO:0030099
  • GO:0030246
  • GO:0033033
  • GO:0043066
  • GO:0045087
Endomucin
10090
  • angiogenesis
  • carbohydrate binding
  • cell-cell adhesion
  • hematopoietic stem cell homeostasis
  • membrane
  • plasma membrane
  • regulation of cell adhesion
  • GO:0001525
  • GO:0005886
  • GO:0016020
  • GO:0030155
  • GO:0030246
  • GO:0061484
  • GO:0098609
Killer cell lectin-like receptor 5
10090
  • carbohydrate binding
  • cell adhesion
  • plasma membrane
  • GO:0005886
  • GO:0007155
  • GO:0030246
Neutral alpha-glucosidase AB
10090
  • Golgi apparatus
  • N-glycan processing
  • alpha-glucosidase activity
  • carbohydrate binding
  • carbohydrate metabolic process
  • endoplasmic reticulum
  • glucan 1,3-alpha-glucosidase activity
  • glucosidase II complex
  • glucosidase activity
  • intracellular membrane-bounded organelle
  • melanosome
  • GO:0005783
  • GO:0005794
  • GO:0005975
  • GO:0006491
  • GO:0015926
  • GO:0017177
  • GO:0030246
  • GO:0033919
  • GO:0042470
  • GO:0043231
  • GO:0090599
Displaying entries 11 - 20 of 2433 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01