GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▼	GO Labels	GO IDs
GL_002051	P-selectin	P98109	Ovis aries	9940	calcium ion binding calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules calcium-dependent protein binding calcium-mediated signaling using intracellular calcium source external side of plasma membrane extracellular space fucose binding heparin binding heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules inflammatory response leukocyte tethering or rolling lipopolysaccharide binding oligosaccharide binding plasma membrane platelet alpha granule membrane positive regulation of leukocyte migration positive regulation of leukocyte tethering or rolling positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of platelet activation regulation of integrin activation sialic acid binding	GO:0001530 GO:0002687 GO:0005509 GO:0005615 GO:0005886 GO:0006954 GO:0007157 GO:0008201 GO:0009897 GO:0010572 GO:0016339 GO:0031092 GO:0033623 GO:0033691 GO:0035584 GO:0042806 GO:0048306 GO:0050901 GO:0051897 GO:0070492 GO:1903238
GL_000478	Galectin-1	P81184	Ovis aries	9940	apoptotic process carbohydrate binding cytoplasm extracellular region	GO:0005576 GO:0005737 GO:0006915 GO:0030246
GL_000315	Chitinase-3-like protein 1	Q6TMG6	Ovis aries	9940	activation of NF-kappaB-inducing kinase activity apoptotic process carbohydrate binding carbohydrate metabolic process cellular response to tumor necrosis factor chitin binding cytoplasm endoplasmic reticulum extracellular space inflammatory response lung development perinuclear region of cytoplasm positive regulation of ERK1 and ERK2 cascade positive regulation of angiogenesis positive regulation of interleukin-8 production positive regulation of peptidyl-threonine phosphorylation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction response to interleukin-1 response to interleukin-6 response to mechanical stimulus response to tumor necrosis factor	GO:0005615 GO:0005737 GO:0005783 GO:0005975 GO:0006915 GO:0006954 GO:0007250 GO:0008061 GO:0009612 GO:0010800 GO:0030246 GO:0030324 GO:0032757 GO:0034612 GO:0045766 GO:0048471 GO:0051897 GO:0070374 GO:0070555 GO:0070741 GO:0071356
GL_001865	Transcriptional regulator LsrR	Q8ZKQ5	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2	99287	DNA binding carbohydrate binding cytoplasm	GO:0003677 GO:0005737 GO:0030246
GL_001551	Glucans biosynthesis protein D	Q8ZPB3	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2	99287	beta-glucan biosynthetic process carbohydrate binding catalytic activity outer membrane-bounded periplasmic space	GO:0003824 GO:0030246 GO:0030288 GO:0051274
GL_001810	Putative glucose-6-phosphate 1-epimerase	Q8ZPV9	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2	99287	carbohydrate binding carbohydrate metabolic process cytoplasm glucose-6-phosphate 1-epimerase activity	GO:0005737 GO:0005975 GO:0030246 GO:0047938
GL_001559	Glucans biosynthesis protein G	P67557	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2	99287	beta-glucan biosynthetic process carbohydrate binding catalytic activity outer membrane-bounded periplasmic space	GO:0003824 GO:0030246 GO:0030288 GO:0051274
GL_001425	D-galactose/methyl-galactoside binding periplasmic protein MglB	P23905	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2	99287	carbohydrate binding carbohydrate transport chemotaxis metal ion binding outer membrane-bounded periplasmic space	GO:0006935 GO:0008643 GO:0030246 GO:0030288 GO:0046872
GL_001885	Uncharacterized protein YiiZ	P43020	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2	99287	carbohydrate binding organic substance transport outer membrane-bounded periplasmic space transmembrane transport	GO:0030246 GO:0030288 GO:0055085 GO:0071702
GL_000316	Chitinase-3-like protein 1	Q8SPQ0	Capra hircus	9925	activation of NF-kappaB-inducing kinase activity apoptotic process carbohydrate binding carbohydrate metabolic process cellular response to tumor necrosis factor chitin binding cytoplasm endoplasmic reticulum extracellular space inflammatory response lung development perinuclear region of cytoplasm positive regulation of ERK1 and ERK2 cascade positive regulation of angiogenesis positive regulation of interleukin-8 production positive regulation of peptidyl-threonine phosphorylation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction response to interleukin-1 response to interleukin-6 response to mechanical stimulus response to tumor necrosis factor	GO:0005615 GO:0005737 GO:0005783 GO:0005975 GO:0006915 GO:0006954 GO:0007250 GO:0008061 GO:0009612 GO:0010800 GO:0030246 GO:0030324 GO:0032757 GO:0034612 GO:0045766 GO:0048471 GO:0051897 GO:0070374 GO:0070555 GO:0070741 GO:0071356