GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID	GO Labels	GO IDs
GL_000429	G-type lectin S-receptor-like serine/threonine-protein kinase At1g61550	Q9SY95	Arabidopsis thaliana	3702	ATP binding calmodulin binding carbohydrate binding phosphorylation plasma membrane protein serine kinase activity protein serine/threonine kinase activity recognition of pollen ubiquitin protein ligase binding	GO:0004674 GO:0005516 GO:0005524 GO:0005886 GO:0016310 GO:0030246 GO:0031625 GO:0048544 GO:0106310
GL_001235	Alpha-mannosidase 2C1	Q9NTJ4	Homo sapiens	9606	alpha-mannosidase activity carbohydrate binding cytosol mannose metabolic process metal ion binding nucleoplasm oligosaccharide catabolic process	GO:0004559 GO:0005654 GO:0005829 GO:0006013 GO:0009313 GO:0030246 GO:0046872
GL_000269	Calreticulin	P18418	Rattus norvegicus	10116	MHC class I peptide loading complex acrosomal vesicle calcium ion binding carbohydrate binding cardiac muscle cell differentiation cell surface cellular response to electrical stimulus cellular response to lithium ion cellular response to organic substance cellular response to virus cellular senescence collagen-containing extracellular matrix complement component C1q complex binding cortical actin cytoskeleton organization cortical granule cytolytic granule cytoplasm cytosol endoplasmic reticulum endoplasmic reticulum lumen endoplasmic reticulum membrane endoplasmic reticulum quality control compartment external side of plasma membrane extracellular space hormone binding integrin binding iron ion binding mRNA binding membrane negative regulation of DNA-templated transcription negative regulation of intracellular steroid hormone receptor signaling pathway negative regulation of neuron differentiation negative regulation of retinoic acid receptor signaling pathway negative regulation of transcription by RNA polymerase II negative regulation of translation negative regulation of trophoblast cell migration nuclear androgen receptor binding nuclear envelope nuclear export signal receptor activity nucleus obsolete selective autophagy peptide antigen assembly with MHC class I protein complex peptide binding perinuclear region of cytoplasm polysome positive regulation of cell cycle positive regulation of cell population proliferation positive regulation of dendritic cell chemotaxis positive regulation of endothelial cell migration positive regulation of gene expression positive regulation of non-canonical NF-kappaB signal transduction positive regulation of phagocytosis positive regulation of substrate adhesion-dependent cell spreading protein export from nucleus protein folding protein localization to nucleus protein stabilization protein-containing complex regulation of meiotic nuclear division response to estradiol response to glycoside response to organic substance response to testosterone response to xenobiotic stimulus sarcoplasmic reticulum sarcoplasmic reticulum lumen smooth endoplasmic reticulum spermatogenesis ubiquitin protein ligase binding ubiquitin-dependent ERAD pathway unfolded protein binding	GO:0000122 GO:0001669 GO:0001849 GO:0002502 GO:0003729 GO:0005049 GO:0005178 GO:0005506 GO:0005509 GO:0005615 GO:0005634 GO:0005635 GO:0005737 GO:0005783 GO:0005788 GO:0005789 GO:0005790 GO:0005829 GO:0005844 GO:0006457 GO:0006611 GO:0007283 GO:0008284 GO:0009410 GO:0009897 GO:0009986 GO:0010033 GO:0010595 GO:0010628 GO:0016020 GO:0016529 GO:0017148 GO:0030246 GO:0030433 GO:0030866 GO:0031625 GO:0032355 GO:0032991 GO:0033018 GO:0033144 GO:0033574 GO:0034504 GO:0040020 GO:0042277 GO:0042562 GO:0042824 GO:0044194 GO:0044322 GO:0045665 GO:0045787 GO:0045892 GO:0048387 GO:0048471 GO:0050681 GO:0050766 GO:0050821 GO:0051082 GO:0055007 GO:0060473 GO:0061912 GO:0062023 GO:0071257 GO:0071285 GO:0071310 GO:0090398 GO:0098586 GO:1900026 GO:1901164 GO:1901224 GO:1903416 GO:2000510
GL_000397	FRAS1-related extracellular matrix protein 1	Q5H8C1	Homo sapiens	9606	anatomical structure morphogenesis basement membrane carbohydrate binding cell communication cell-matrix adhesion collagen-containing extracellular matrix craniofacial suture morphogenesis extracellular region membrane metal ion binding	GO:0005576 GO:0005604 GO:0007154 GO:0007160 GO:0009653 GO:0016020 GO:0030246 GO:0046872 GO:0062023 GO:0097094
GL_001967	Agglutinin (BOA)	R4GRU1	Burkholderia oklahomensis	342113	carbohydrate binding	GO:0030246
GL_001394	Central glycolytic genes regulator	P35168	Priestia megaterium DSM 319	592022	DNA binding carbohydrate binding	GO:0003677 GO:0030246
GL_001832	Secreted beta-glucosidase sun1	Q4WGL5	Aspergillus fumigatus Af293	330879	(1->3)-beta-D-glucan catabolic process carbohydrate binding cell surface extracellular region fungal-type cell wall fungal-type cell wall organization hydrolase activity, acting on glycosyl bonds hyphal growth	GO:0005576 GO:0006076 GO:0009277 GO:0009986 GO:0016798 GO:0030246 GO:0030448 GO:0031505
GL_000364	Eosinophil granule major basic protein 1	P22032	Cavia porcellus	10141	carbohydrate binding defense response to bacterium immune response	GO:0006955 GO:0030246 GO:0042742
GL_002384	CD83 antigen	Q01151	Homo sapiens	9606	CD4-positive, alpha-beta T cell differentiation defense response external side of plasma membrane humoral immune response negative regulation of interleukin-4 production plasma membrane positive regulation of CD4-positive, alpha-beta T cell differentiation positive regulation of interleukin-10 production positive regulation of interleukin-2 production response to organic cyclic compound signal transduction	GO:0005886 GO:0006952 GO:0006959 GO:0007165 GO:0009897 GO:0014070 GO:0032713 GO:0032733 GO:0032743 GO:0043367 GO:0043372
GL_000160	C-type lectin domain family 2 member D6	A4KWA8	Rattus norvegicus	10116	carbohydrate binding external side of plasma membrane natural killer cell lectin-like receptor binding	GO:0009897 GO:0030246 GO:0046703