GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID ▲	Species	Taxonomy ID	GO Labels	GO IDs
GL_002260	Capsid	Q91H09	Human calicivirus NLV/VA97207/1997	165510
GL_000154	C-type lectin domain family 2 member D	Q91V08	Mus musculus	10090	carbohydrate binding cell surface cellular defense response endoplasmic reticulum external side of plasma membrane natural killer cell lectin-like receptor binding negative regulation of osteoclast differentiation plasma membrane protection from natural killer cell mediated cytotoxicity transmembrane signaling receptor activity	GO:0004888 GO:0005783 GO:0005886 GO:0006968 GO:0009897 GO:0009986 GO:0030246 GO:0042270 GO:0045671 GO:0046703
GL_000362	Endosialin	Q91V98	Mus musculus	10090	anatomical structure regression calcium ion binding carbohydrate binding cell migration cytoplasm endothelial cell apoptotic process external side of plasma membrane extracellular matrix binding extracellular matrix protein binding fibroblast migration fibroblast proliferation lymph node development plasma membrane positive regulation of endothelial cell apoptotic process positive regulation of fibroblast proliferation	GO:0005509 GO:0005737 GO:0005886 GO:0009897 GO:0010761 GO:0016477 GO:0030246 GO:0048144 GO:0048146 GO:0048535 GO:0050840 GO:0060033 GO:0072577 GO:1990430 GO:2000353
GL_002016	Galectin-12	Q91VD1	Mus musculus	10090	cytoplasm intrinsic apoptotic signaling pathway lactose binding mitochondrion nucleus	GO:0005634 GO:0005737 GO:0005739 GO:0030395 GO:0097193
GL_000973	Protein FAM3C	Q91VU0	Mus musculus	10090	Golgi apparatus carbohydrate binding cytoplasmic vesicle extracellular space	GO:0005615 GO:0005794 GO:0030246 GO:0031410
GL_001234	Alpha-mannosidase 2C1	Q91W89	Mus musculus	10090	alpha-mannosidase activity carbohydrate binding cytosol mannose metabolic process metal ion binding nucleoplasm oligosaccharide catabolic process	GO:0004559 GO:0005654 GO:0005829 GO:0006013 GO:0009313 GO:0030246 GO:0046872
GL_001628	Glucokinase regulatory protein	Q91X44	Mus musculus	10090	carbohydrate binding carbohydrate derivative metabolic process carbohydrate metabolic process cytoplasm cytosol enzyme binding enzyme inhibitor activity fructose-6-phosphate binding glucose homeostasis glucose sensor activity intracellular glucose homeostasis kinase binding kinase inhibitor activity mitochondrion negative regulation of glucokinase activity nucleoplasm nucleus positive regulation of glucokinase activity protein domain specific binding protein import into nucleus protein localization to nucleus response to fructose response to glucose triglyceride homeostasis urate metabolic process	GO:0001678 GO:0004857 GO:0005634 GO:0005654 GO:0005737 GO:0005739 GO:0005829 GO:0005975 GO:0006606 GO:0009749 GO:0009750 GO:0019210 GO:0019899 GO:0019900 GO:0019904 GO:0030246 GO:0033132 GO:0033133 GO:0034504 GO:0042593 GO:0046415 GO:0070095 GO:0070328 GO:0141089 GO:1901135
GL_000986	Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1	Q91X88	Mus musculus	10090	Golgi membrane O-glycan processing acetylglucosaminyltransferase activity basement membrane organization beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity brain development carbohydrate binding dentate gyrus development gene expression localization of cell manganese ion binding membrane myelination protein O-linked glycosylation protein O-linked mannosylation protein glycosylation protein modification process reactive gliosis sensory perception of sound	GO:0000139 GO:0006486 GO:0006493 GO:0007420 GO:0007605 GO:0008375 GO:0010467 GO:0016020 GO:0016266 GO:0021542 GO:0030145 GO:0030246 GO:0035269 GO:0036211 GO:0042552 GO:0047223 GO:0051674 GO:0071711 GO:0150103
GL_001678	Laforin	Q91XQ2	Rattus norvegicus	10116	L-glutamate transmembrane transport Wnt signaling pathway autophagosome assembly autophagy calcium ion transport carbohydrate binding carbohydrate phosphatase activity carbohydrate phosphorylation cytoplasm cytoplasmic side of endoplasmic reticulum membrane cytoplasmic side of rough endoplasmic reticulum membrane cytosol dendrite dephosphorylation glial cell proliferation glycogen (starch) synthase activity glycogen binding glycogen biosynthetic process glycogen metabolic process habituation identical protein binding macromolecule metabolic process mitochondrion organization myosin phosphatase activity negative regulation of TOR signaling negative regulation of cell cycle negative regulation of gene expression negative regulation of peptidyl-serine phosphorylation nervous system development nucleus perikaryon phosphatase activity phosphoprotein phosphatase activity plasma membrane polysaccharide binding positive regulation of macroautophagy proteasome-mediated ubiquitin-dependent protein catabolic process protein homodimerization activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity protein tyrosine/serine/threonine phosphatase activity regulation of cell growth regulation of gene expression regulation of phosphorylation regulation of proteasomal protein catabolic process regulation of protein import into nucleus regulation of protein localization to plasma membrane regulation of protein phosphorylation regulation of protein ubiquitination starch binding	GO:0000045 GO:0001558 GO:0001932 GO:0004373 GO:0004721 GO:0004722 GO:0004725 GO:0005634 GO:0005737 GO:0005829 GO:0005886 GO:0005977 GO:0005978 GO:0006816 GO:0006914 GO:0007005 GO:0007399 GO:0008138 GO:0010468 GO:0010629 GO:0014009 GO:0015813 GO:0016055 GO:0016239 GO:0016311 GO:0016791 GO:0017018 GO:0019203 GO:0030246 GO:0030247 GO:0030425 GO:0031396 GO:0032007 GO:0033137 GO:0042306 GO:0042325 GO:0042802 GO:0042803 GO:0043161 GO:0043170 GO:0043204 GO:0045786 GO:0046835 GO:0046959 GO:0061136 GO:0098554 GO:0098556 GO:1903076 GO:2001069 GO:2001070
GL_002073	Sialic acid-binding Ig-like lectin 12	Q91Y57	Mus musculus	10090	cell adhesion external side of plasma membrane inflammatory response membrane monosaccharide binding negative regulation of inflammatory response negative regulation of phagocytosis, engulfment phagocytosis, engulfment plasma membrane sialic acid binding	GO:0005886 GO:0006911 GO:0006954 GO:0007155 GO:0009897 GO:0016020 GO:0033691 GO:0048029 GO:0050728 GO:0060101