GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin ▲	Lectin Name	UniProt ID	Species	Taxonomy ID	GO Labels	GO IDs
GL_002041	Lithostathine-1-alpha	P05451	Homo sapiens	9606	antimicrobial humoral immune response mediated by antimicrobial peptide extracellular exosome extracellular space growth factor activity molecular function inhibitor activity oligosaccharide binding peptidoglycan binding positive regulation of cell population proliferation response to peptide hormone signaling receptor activity	GO:0005615 GO:0008083 GO:0008284 GO:0038023 GO:0042834 GO:0043434 GO:0061844 GO:0070062 GO:0070492 GO:0140678
GL_002042	Lithostathine-1-beta	P48304	Homo sapiens	9606	antimicrobial humoral immune response mediated by antimicrobial peptide extracellular exosome extracellular space oligosaccharide binding peptidoglycan binding positive regulation of cell population proliferation response to peptide hormone signaling receptor activity	GO:0005615 GO:0008284 GO:0038023 GO:0042834 GO:0043434 GO:0061844 GO:0070062 GO:0070492
GL_002043	Lithostathine-2	Q08731	Mus musculus	10090	antimicrobial humoral immune response mediated by antimicrobial peptide collagen-containing extracellular matrix extracellular space molecular function inhibitor activity myelination oligosaccharide binding peptidoglycan binding positive regulation of cell population proliferation response to peptide hormone signaling receptor activity suckling behavior	GO:0001967 GO:0005615 GO:0008284 GO:0038023 GO:0042552 GO:0042834 GO:0043434 GO:0061844 GO:0062023 GO:0070492 GO:0140678
GL_002044	Macrophage mannose receptor 1	Q61830	Mus musculus	10090	cargo receptor activity cell surface cellular response to interleukin-4 cellular response to lipopolysaccharide cellular response to type II interferon endosome membrane mannose binding plasma membrane receptor-mediated endocytosis signaling receptor activity transmembrane signaling receptor activity	GO:0004888 GO:0005537 GO:0005886 GO:0006898 GO:0009986 GO:0010008 GO:0038023 GO:0038024 GO:0071222 GO:0071346 GO:0071353
GL_002045	Macrophage mannose receptor 1	P22897	Homo sapiens	9606	cargo receptor activity cell surface cellular response to interleukin-4 cellular response to lipopolysaccharide cellular response to type II interferon endosome membrane mannose binding plasma membrane receptor-mediated endocytosis signaling receptor activity transmembrane signaling receptor activity virus receptor activity	GO:0001618 GO:0004888 GO:0005537 GO:0005886 GO:0006898 GO:0009986 GO:0010008 GO:0038023 GO:0038024 GO:0071222 GO:0071346 GO:0071353
GL_002046	Mannose/glucose-specific lectin	C0HLR9	Parkia pendula	1905032	glucose binding mannose binding	GO:0005536 GO:0005537
GL_002047	P-selectin	P16109	Homo sapiens	9606	calcium ion binding calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules calcium-dependent protein binding calcium-mediated signaling using intracellular calcium source cell adhesion defense response to Gram-negative bacterium external side of plasma membrane extracellular space fucose binding glycosphingolipid binding heparin binding heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules inflammatory response leukocyte cell-cell adhesion leukocyte tethering or rolling lipopolysaccharide binding oligosaccharide binding plasma membrane platelet alpha granule membrane platelet dense granule membrane positive regulation of leukocyte migration positive regulation of leukocyte tethering or rolling positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of platelet activation regulation of integrin activation response to cytokine response to lipopolysaccharide sialic acid binding	GO:0001530 GO:0002687 GO:0005509 GO:0005615 GO:0005886 GO:0006954 GO:0007155 GO:0007157 GO:0007159 GO:0008201 GO:0009897 GO:0010572 GO:0016339 GO:0031088 GO:0031092 GO:0032496 GO:0033623 GO:0033691 GO:0034097 GO:0035584 GO:0042806 GO:0043208 GO:0048306 GO:0050829 GO:0050901 GO:0051897 GO:0070492 GO:1903238
GL_002048	P-selectin	Q01102	Mus musculus	10090	calcium ion binding calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules calcium-dependent protein binding calcium-mediated signaling using intracellular calcium source cell-cell adhesion cellular response to interleukin-6 external side of plasma membrane extracellular space fucose binding heparin binding heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules inflammatory response leukocyte cell-cell adhesion leukocyte migration leukocyte tethering or rolling lipopolysaccharide binding membrane oligosaccharide binding plasma membrane platelet alpha granule membrane positive regulation of cell adhesion positive regulation of leukocyte migration positive regulation of leukocyte tethering or rolling positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of platelet activation regulation of cellular extravasation regulation of integrin activation response to cytokine sialic acid binding	GO:0001530 GO:0002687 GO:0002691 GO:0005509 GO:0005615 GO:0005886 GO:0006954 GO:0007157 GO:0007159 GO:0008201 GO:0009897 GO:0010572 GO:0016020 GO:0016339 GO:0031092 GO:0033623 GO:0033691 GO:0034097 GO:0035584 GO:0042806 GO:0045785 GO:0048306 GO:0050900 GO:0050901 GO:0051897 GO:0070492 GO:0071354 GO:0098609 GO:1903238
GL_002049	P-selectin	P42201	Bos taurus	9913	calcium ion binding calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules external side of plasma membrane extracellular space heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte tethering or rolling oligosaccharide binding plasma membrane positive regulation of leukocyte tethering or rolling response to cytokine sialic acid binding	GO:0005509 GO:0005615 GO:0005886 GO:0007157 GO:0009897 GO:0016339 GO:0033691 GO:0034097 GO:0050901 GO:0070492 GO:1903238
GL_002050	P-selectin	P98106	Rattus norvegicus	10116	calcium ion binding calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules calcium-dependent protein binding calcium-mediated signaling using intracellular calcium source cell-cell adhesion external side of plasma membrane extracellular space fucose binding heparin binding heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules inflammatory response leukocyte cell-cell adhesion leukocyte migration leukocyte tethering or rolling lipopolysaccharide binding membrane oligosaccharide binding plasma membrane platelet alpha granule membrane positive regulation of cell adhesion positive regulation of leukocyte migration positive regulation of leukocyte tethering or rolling positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of platelet activation regulation of cellular extravasation regulation of integrin activation response to cytokine response to lipopolysaccharide response to organic cyclic compound sialic acid binding	GO:0001530 GO:0002687 GO:0002691 GO:0005509 GO:0005615 GO:0005886 GO:0006954 GO:0007157 GO:0007159 GO:0008201 GO:0009897 GO:0010572 GO:0014070 GO:0016020 GO:0016339 GO:0031092 GO:0032496 GO:0033623 GO:0033691 GO:0034097 GO:0035584 GO:0042806 GO:0045785 GO:0048306 GO:0050900 GO:0050901 GO:0051897 GO:0070492 GO:0098609 GO:1903238