GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▲	GO Labels	GO IDs
GL_000286	Calreticulin	Q2HWU3	Macaca fuscata fuscata	9543	calcium ion binding carbohydrate binding cell surface cortical granule cytolytic granule cytosol extracellular region protein folding protein stabilization sarcoplasmic reticulum lumen unfolded protein binding	GO:0005509 GO:0005576 GO:0005829 GO:0006457 GO:0009986 GO:0030246 GO:0033018 GO:0044194 GO:0050821 GO:0051082 GO:0060473
GL_000799	Natural killer cells antigen CD94	Q9MZK9	Macaca mulatta	9544	carbohydrate binding external side of plasma membrane negative regulation of T cell mediated cytotoxicity negative regulation of natural killer cell mediated cytotoxicity plasma membrane positive regulation of natural killer cell mediated cytotoxicity stimulatory C-type lectin receptor signaling pathway transmembrane signaling receptor activity	GO:0001915 GO:0002223 GO:0004888 GO:0005886 GO:0009897 GO:0030246 GO:0045953 GO:0045954
GL_000828	NKG2-D type II integral membrane protein	Q9MZJ7	Macaca mulatta	9544	adaptive immune response carbohydrate binding cell differentiation cell surface external side of plasma membrane innate immune response positive regulation of natural killer cell mediated cytotoxicity signaling receptor activity	GO:0002250 GO:0009897 GO:0009986 GO:0030154 GO:0030246 GO:0038023 GO:0045087 GO:0045954
GL_002031	L-selectin	Q95198	Macaca mulatta	9544	calcium ion binding calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules external side of plasma membrane extracellular space heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte tethering or rolling oligosaccharide binding plasma membrane response to cytokine sialic acid binding	GO:0005509 GO:0005615 GO:0005886 GO:0007157 GO:0009897 GO:0016339 GO:0033691 GO:0034097 GO:0050901 GO:0070492
GL_001012	Pulmonary surfactant-associated protein A	Q9TUC5	Macaca mulatta	9544	carbohydrate binding collagen trimer extracellular space metal ion binding multivesicular body respiratory gaseous exchange by respiratory system	GO:0005581 GO:0005615 GO:0005771 GO:0007585 GO:0030246 GO:0046872
GL_001995	C-type lectin domain family 7 member A	Q8HZR8	Macaca mulatta	9544	(1->3)-beta-D-glucan binding antifungal innate immune response cell surface cellular response to molecule of fungal origin detection of fungus detection of molecule of fungal origin inflammatory response metal ion binding pattern recognition receptor activity phagocytosis, recognition plasma membrane positive regulation of T-helper 17 type immune response positive regulation of canonical NF-kappaB signal transduction positive regulation of cell migration positive regulation of cell population proliferation positive regulation of cytokine production involved in inflammatory response positive regulation of killing of cells of another organism positive regulation of lymphocyte activation positive regulation of phagocytosis positive regulation of wound healing	GO:0001872 GO:0005886 GO:0006910 GO:0006954 GO:0008284 GO:0009986 GO:0016046 GO:0030335 GO:0032491 GO:0038187 GO:0043123 GO:0046872 GO:0050766 GO:0051251 GO:0051712 GO:0061760 GO:0071226 GO:0090303 GO:1900017 GO:2000318
GL_000816	NKG2-A/NKG2-B type II integral membrane protein	Q9MZJ3	Macaca mulatta	9544	CD8-positive, gamma-delta intraepithelial T cell differentiation HLA-E specific inhibitory MHC class Ib receptor activity adaptive immune response carbohydrate binding external side of plasma membrane innate immune response negative regulation of T cell mediated cytotoxicity negative regulation of natural killer cell mediated cytotoxicity plasma membrane positive regulation of natural killer cell mediated cytotoxicity stimulatory C-type lectin receptor signaling pathway transmembrane signaling receptor activity	GO:0001915 GO:0002223 GO:0002250 GO:0002305 GO:0004888 GO:0005886 GO:0009897 GO:0030246 GO:0045087 GO:0045953 GO:0045954 GO:0062082
GL_000819	NKG2-C type II integral membrane protein	Q9MZK6	Macaca mulatta	9544	activating MHC class Ib receptor activity adaptive immune response carbohydrate binding external side of plasma membrane innate immune response plasma membrane positive regulation of natural killer cell degranulation positive regulation of natural killer cell mediated cytotoxicity stimulatory C-type lectin receptor signaling pathway transmembrane signaling receptor activity	GO:0002223 GO:0002250 GO:0004888 GO:0005886 GO:0009897 GO:0030246 GO:0043323 GO:0045087 GO:0045954 GO:0062081
GL_001024	Pulmonary surfactant-associated protein D	Q1PBC5	Macaca mulatta	9544	carbohydrate binding collagen trimer extracellular space innate immune response lung alveolus development multivesicular body positive regulation of phagocytosis regulation of immune system process respiratory gaseous exchange by respiratory system surfactant homeostasis	GO:0002682 GO:0005581 GO:0005615 GO:0005771 GO:0007585 GO:0030246 GO:0043129 GO:0045087 GO:0048286 GO:0050766
GL_001172	Versican core protein (Fragments)	Q28858	Macaca nemestrina	9545	calcium ion binding carbohydrate binding cell adhesion extracellular region hyaluronic acid binding interphotoreceptor matrix photoreceptor outer segment	GO:0001750 GO:0005509 GO:0005540 GO:0005576 GO:0007155 GO:0030246 GO:0033165