GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID ▲	Species	Taxonomy ID	GO Labels	GO IDs
GL_000815	NKG2-A/NKG2-B type II integral membrane protein	Q95MI5	Pan troglodytes	9598	CD8-positive, gamma-delta intraepithelial T cell differentiation HLA-E specific inhibitory MHC class Ib receptor activity MHC class I protein complex binding adaptive immune response carbohydrate binding external side of plasma membrane innate immune response natural killer cell inhibitory signaling pathway negative regulation of T cell mediated cytotoxicity negative regulation of natural killer cell mediated cytotoxicity plasma membrane positive regulation of natural killer cell mediated cytotoxicity receptor complex stimulatory C-type lectin receptor signaling pathway transmembrane signaling receptor activity	GO:0001915 GO:0002223 GO:0002250 GO:0002305 GO:0002769 GO:0004888 GO:0005886 GO:0009897 GO:0023024 GO:0030246 GO:0043235 GO:0045087 GO:0045953 GO:0045954 GO:0062082
GL_000923	Polypeptide N-acetylgalactosaminyltransferase 5	Q95ZJ1	Caenorhabditis elegans	6239	Golgi apparatus Golgi membrane carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation protein O-linked glycosylation via threonine	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0018243 GO:0030246 GO:0046872
GL_000657	L-type lectin-domain containing receptor kinase V.5	Q96285	Arabidopsis thaliana	3702	ATP binding carbohydrate binding defense response to bacterium defense response to oomycetes negative regulation of defense response to bacterium plasma membrane protein autophosphorylation protein serine kinase activity protein serine/threonine kinase activity regulation of stomatal closure	GO:0002229 GO:0004674 GO:0005524 GO:0005886 GO:0030246 GO:0042742 GO:0046777 GO:0090333 GO:0106310 GO:1900425
GL_001503	Galactose-3-O-sulfotransferase 3	Q96A11	Homo sapiens	9606	3'-phosphoadenosine 5'-phosphosulfate binding Golgi cisterna membrane carbohydrate binding galactose 3-O-sulfotransferase activity galactosylceramide sulfotransferase activity glycolipid biosynthetic process membrane monosaccharide metabolic process oligosaccharide metabolic process poly-N-acetyllactosamine metabolic process proteoglycan biosynthetic process proteoglycan sulfotransferase activity sulfur compound metabolic process	GO:0001733 GO:0005996 GO:0006790 GO:0009247 GO:0009311 GO:0016020 GO:0030166 GO:0030246 GO:0030309 GO:0032580 GO:0050656 GO:0050694 GO:0050698
GL_000980	Protein FAM3D	Q96BQ1	Homo sapiens	9606	carbohydrate binding cytokine activity extracellular region extracellular space negative regulation of insulin secretion	GO:0005125 GO:0005576 GO:0005615 GO:0030246 GO:0046676
GL_001497	Galactose mutarotase	Q96C23	Homo sapiens	9606	aldose 1-epimerase activity carbohydrate binding carbohydrate metabolic process cytoplasm extracellular exosome galactose catabolic process via UDP-galactose galactose metabolic process glucose metabolic process	GO:0004034 GO:0005737 GO:0005975 GO:0006006 GO:0006012 GO:0030246 GO:0033499 GO:0070062
GL_000842	Pancreatic adenocarcinoma up-regulated factor	Q96DA0	Homo sapiens	9606	carbohydrate binding extracellular exosome extracellular space	GO:0005615 GO:0030246 GO:0070062
GL_002017	Galectin-12	Q96DT0	Homo sapiens	9606	cytoplasm intrinsic apoptotic signaling pathway lactose binding mitochondrion nucleus	GO:0005634 GO:0005737 GO:0005739 GO:0030395 GO:0097193
GL_000629	Killer cell lectin-like receptor subfamily G member 1	Q96E93	Homo sapiens	9606	carbohydrate binding cell surface receptor signaling pathway cellular defense response inflammatory response innate immune response intracellular membrane-bounded organelle membrane plasma membrane signaling receptor activity	GO:0005886 GO:0006954 GO:0006968 GO:0007166 GO:0016020 GO:0030246 GO:0038023 GO:0043231 GO:0045087
GL_000900	Polypeptide N-acetylgalactosaminyltransferase 14	Q96FL9	Homo sapiens	9606	Golgi apparatus Golgi membrane O-glycan processing carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0016266 GO:0030246 GO:0046872