GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▼	GO Labels	GO IDs
GL_001369	Beta-hexosaminidase subunit beta	Q6AXR4	Rattus norvegicus	10116	N-acetyl-beta-D-galactosaminidase activity N-acetylglucosamine metabolic process acetylglucosaminyltransferase activity acrosomal vesicle astrocyte cell migration azurophil granule beta-N-acetylglucosaminidase activity beta-N-acetylhexosaminidase activity beta-N-acetylhexosaminidase complex carbohydrate binding chondroitin sulfate catabolic process cortical granule dermatan sulfate catabolic process extracellular space ganglioside catabolic process glycosaminoglycan metabolic process glycosphingolipid metabolic process hexosaminidase activity hyaluronan catabolic process hydrolase activity identical protein binding intracellular calcium ion homeostasis lipid storage locomotory behavior lysosome lysosome organization maintenance of location in cell male courtship behavior membrane myelination neuromuscular process neuromuscular process controlling balance neuron cellular homeostasis oligosaccharide catabolic process oogenesis penetration of zona pellucida phospholipid biosynthetic process positive regulation of transcription by RNA polymerase II protein metabolic process protein-containing complex binding regulation of cell shape sensory perception of sound sexual reproduction single fertilization skeletal system development	GO:0001501 GO:0001669 GO:0004563 GO:0005615 GO:0005764 GO:0006044 GO:0006687 GO:0006689 GO:0006874 GO:0007040 GO:0007338 GO:0007341 GO:0007605 GO:0007626 GO:0008049 GO:0008360 GO:0008375 GO:0008654 GO:0009313 GO:0015929 GO:0016020 GO:0016231 GO:0016787 GO:0019538 GO:0019915 GO:0019953 GO:0030203 GO:0030207 GO:0030209 GO:0030214 GO:0030246 GO:0042552 GO:0042582 GO:0042802 GO:0043615 GO:0044877 GO:0045944 GO:0048477 GO:0050885 GO:0050905 GO:0051651 GO:0060473 GO:0070050 GO:0102148 GO:1905379
GL_000618	Killer cell lectin-like receptor subfamily B member 1B allele B	Q5NKN4	Rattus norvegicus	10116	carbohydrate binding cell surface plasma membrane regulation of natural killer cell mediated cytotoxicity signaling receptor activity	GO:0005886 GO:0009986 GO:0030246 GO:0038023 GO:0042269
GL_000073	Attractin	Q99J86	Rattus norvegicus	10116	Notch binding carbohydrate binding cerebellum development extracellular space inflammatory response myelination pigmentation plasma membrane regulation of multicellular organism growth response to oxidative stress signaling receptor activity	GO:0005112 GO:0005615 GO:0005886 GO:0006954 GO:0006979 GO:0021549 GO:0030246 GO:0038023 GO:0040014 GO:0042552 GO:0043473
GL_000475	Galectin-1	P11762	Rattus norvegicus	10116	T cell costimulation apoptotic process carbohydrate binding cell surface cell-cell adhesion cellular response to glucose stimulus cellular response to organic cyclic compound cytoplasm extracellular space galectin complex identical protein binding lactose binding laminin binding myoblast differentiation negative regulation of cell-substrate adhesion negative regulation of neuron projection development plasma cell differentiation positive regulation of apoptotic process positive regulation of erythrocyte aggregation positive regulation of inflammatory response positive regulation of viral entry into host cell response to axon injury response to isolation stress response to xenobiotic stimulus	GO:0002317 GO:0005615 GO:0005737 GO:0006915 GO:0009410 GO:0009986 GO:0010812 GO:0010977 GO:0030246 GO:0030395 GO:0031295 GO:0034120 GO:0035900 GO:0042802 GO:0043065 GO:0043236 GO:0045445 GO:0046598 GO:0048678 GO:0050729 GO:0071333 GO:0071407 GO:0098609 GO:1990724
GL_001642	Glycogen phosphorylase, liver form	P09811	Rattus norvegicus	10116	5-phosphoribose 1-diphosphate biosynthetic process AMP binding ATP binding SHG alpha-glucan phosphorylase activity bile acid binding carbohydrate binding cytoplasm cytosol glucose binding glucose homeostasis glycogen catabolic process glycogen metabolic process glycogen phosphorylase activity identical protein binding linear malto-oligosaccharide phosphorylase activity necroptotic process purine nucleobase binding pyridoxal phosphate binding response to bacterium vitamin binding	GO:0002060 GO:0005524 GO:0005536 GO:0005737 GO:0005829 GO:0005977 GO:0005980 GO:0006015 GO:0008184 GO:0009617 GO:0016208 GO:0019842 GO:0030170 GO:0030246 GO:0032052 GO:0042593 GO:0042802 GO:0070266 GO:0102250 GO:0102499
GL_001743	Pleiotrophin	P63090	Rattus norvegicus	10116	Schaffer collateral - CA1 synapse basement membrane bone mineralization carbohydrate binding cell surface cellular response to UV cellular response to hypoxia cellular response to organic cyclic compound cellular response to platelet-derived growth factor stimulus cellular response to vitamin D cerebellum development chondroitin sulfate binding chondroitin sulfate proteoglycan binding decidualization dendrite arborization dendrite regeneration endothelial cell differentiation estrous cycle extracellular region extracellular space glycosaminoglycan binding growth factor activity heart development heparan sulfate binding heparin binding hindbrain development integrin binding integrin-mediated signaling pathway learning leukocyte chemotaxis involved in inflammatory response liver development long-term synaptic potentiation lung development memory modulation of chemical synaptic transmission molecular function activator activity negative regulation of angiogenesis negative regulation of cell migration negative regulation of epithelial cell proliferation negative regulation of glial cell proliferation negative regulation of long-term synaptic potentiation negative regulation of membrane potential negative regulation of mesenchymal cell proliferation negative regulation of neuroblast proliferation negative regulation of neuromuscular junction development neuromuscular junction oogenesis ossification ossification involved in bone remodeling perinuclear region of cytoplasm plasma membrane positive regulation of apoptotic process positive regulation of axon regeneration positive regulation of bone mineralization positive regulation of cell differentiation positive regulation of cell division positive regulation of cell population proliferation positive regulation of cell-substrate adhesion positive regulation of dendrite development positive regulation of hepatocyte proliferation positive regulation of leukocyte chemotaxis positive regulation of neuron projection development positive regulation of oligodendrocyte differentiation positive regulation of ossification positive regulation of skeletal muscle acetylcholine-gated channel clustering positive regulation of stem cell differentiation postsynapse presynapse protein kinase binding protein phosphatase inhibitor activity protein-containing complex proteoglycan binding receptor clustering regulation of cell shape regulation of endothelial cell migration regulation of hemopoiesis regulation of myelination regulation of stem cell population maintenance regulation of synaptic plasticity response to activity response to auditory stimulus response to ciliary neurotrophic factor response to estradiol response to kainic acid response to nerve growth factor response to progesterone response to xenobiotic stimulus retina development in camera-type eye retinal rod cell differentiation rod bipolar cell differentiation spinal cord development syndecan binding thalamus development tissue regeneration vascular endothelial growth factor binding	GO:0001503 GO:0001889 GO:0002232 GO:0002690 GO:0004864 GO:0005178 GO:0005539 GO:0005576 GO:0005604 GO:0005615 GO:0005886 GO:0007229 GO:0007406 GO:0007507 GO:0007612 GO:0007613 GO:0008083 GO:0008201 GO:0008284 GO:0008360 GO:0009410 GO:0009986 GO:0010594 GO:0010811 GO:0010976 GO:0010996 GO:0014823 GO:0016525 GO:0019901 GO:0021510 GO:0021549 GO:0021794 GO:0030246 GO:0030282 GO:0030324 GO:0030336 GO:0030501 GO:0030902 GO:0031104 GO:0031594 GO:0031641 GO:0032355 GO:0032570 GO:0032991 GO:0034644 GO:0035373 GO:0035374 GO:0036120 GO:0038085 GO:0042246 GO:0043065 GO:0043113 GO:0043394 GO:0043932 GO:0044849 GO:0045446 GO:0045545 GO:0045597 GO:0045778 GO:0045837 GO:0046697 GO:0048167 GO:0048471 GO:0048477 GO:0048680 GO:0048714 GO:0050680 GO:0050804 GO:0051781 GO:0060041 GO:0060221 GO:0060253 GO:0060291 GO:0071305 GO:0071407 GO:0071456 GO:0072201 GO:0098685 GO:0098793 GO:0098794 GO:0140059 GO:0140677 GO:1900006 GO:1900272 GO:1903706 GO:1904373 GO:1904389 GO:1904391 GO:1904395 GO:1904397 GO:1904399 GO:1990089 GO:2000036 GO:2000347 GO:2000738
GL_000622	Killer cell lectin-like receptor subfamily B member 1F	Q63378	Rattus norvegicus	10116	carbohydrate binding cell surface plasma membrane regulation of natural killer cell mediated cytotoxicity signaling receptor activity	GO:0005886 GO:0009986 GO:0030246 GO:0038023 GO:0042269
GL_000390	Ficolin-2	P57756	Rattus norvegicus	10116	G protein-coupled receptor binding G protein-coupled receptor signaling pathway antigen binding carbohydrate binding carbohydrate derivative binding cell surface pattern recognition receptor signaling pathway collagen trimer collagen-containing extracellular matrix complement activation, lectin pathway extracellular space metal ion binding negative regulation of viral entry into host cell pattern recognition receptor activity plasma membrane positive regulation of interleukin-8 production positive regulation of opsonization protein localization to cell surface proteolysis recognition of apoptotic cell serine-type endopeptidase complex sialic acid binding signaling receptor binding	GO:0001664 GO:0001867 GO:0002752 GO:0003823 GO:0005102 GO:0005581 GO:0005615 GO:0005886 GO:0006508 GO:0007186 GO:0030246 GO:0032757 GO:0033691 GO:0034394 GO:0038187 GO:0043654 GO:0046597 GO:0046872 GO:0062023 GO:0097367 GO:1903028 GO:1905370
GL_001704	Malectin	Q5FVQ4	Rattus norvegicus	10116	carbohydrate binding carbohydrate metabolic process endoplasmic reticulum enzyme binding membrane oligosaccharyltransferase complex protein N-linked glycosylation	GO:0005783 GO:0005975 GO:0006487 GO:0008250 GO:0016020 GO:0019899 GO:0030246
GL_001782	Protein AMBP	Q64240	Rattus norvegicus	10116	IgA binding carbohydrate binding cell surface cytosol endoplasmic reticulum extracellular space heme binding mitochondrial inner membrane nuclear membrane oxidoreductase activity plasma membrane protein catabolic process protein homodimerization activity serine-type endopeptidase inhibitor activity	GO:0004867 GO:0005615 GO:0005743 GO:0005783 GO:0005829 GO:0005886 GO:0009986 GO:0016491 GO:0019862 GO:0020037 GO:0030163 GO:0030246 GO:0031965 GO:0042803