GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID ▲	Species	Taxonomy ID	GO Labels	GO IDs
GL_002264	Tail spike protein	Q9AYY6	Enterobacteria phage HK620	155148	virion component	GO:0044423
GL_001730	Neutral alpha-glucosidase C (Fragment)	Q9BE70	Macaca fascicularis	9541	carbohydrate binding maltose alpha-glucosidase activity	GO:0030246 GO:0032450
GL_001829	Sclerostin	Q9BQB4	Homo sapiens	9606	BMP binding BMP signaling pathway DNA-binding transcription factor binding Golgi apparatus canonical Wnt signaling pathway carbohydrate binding cellular response to parathyroid hormone stimulus extracellular region extracellular space heparin binding localization molecular function inhibitor activity negative regulation of BMP signaling pathway negative regulation of Wnt signaling pathway negative regulation of canonical Wnt signaling pathway negative regulation of ossification negative regulation of protein-containing complex assembly ossification positive regulation of DNA-templated transcription protein-containing complex response to mechanical stimulus	GO:0001503 GO:0005576 GO:0005615 GO:0005794 GO:0008201 GO:0009612 GO:0030178 GO:0030246 GO:0030279 GO:0030509 GO:0030514 GO:0031333 GO:0032991 GO:0036122 GO:0045893 GO:0051179 GO:0060070 GO:0071374 GO:0090090 GO:0140297 GO:0140678
GL_002404	Collectin-11	Q9BWP8	Homo sapiens	9606	DNA binding antimicrobial humoral response calcium ion binding calcium-dependent carbohydrate binding cell surface pattern recognition receptor signaling pathway collagen trimer complement activation complement activation, lectin pathway developmental process execution phase of apoptosis external side of plasma membrane extracellular region extracellular space fucose binding identical protein binding mannose binding oligosaccharide binding positive regulation of opsonization proteolysis serine-type endopeptidase complex	GO:0001867 GO:0002752 GO:0003677 GO:0005509 GO:0005537 GO:0005576 GO:0005581 GO:0005615 GO:0006508 GO:0006956 GO:0009897 GO:0019730 GO:0032502 GO:0042802 GO:0042806 GO:0070492 GO:0097194 GO:0120153 GO:1903028 GO:1905370
GL_002405	Chitinase domain-containing protein 1	Q9BWS9	Homo sapiens	9606	carbohydrate metabolic process chitin binding endomembrane system extracellular exosome extracellular region extracellular space innate immune response late endosome lysosomal lumen lysosome membrane negative regulation of cytokine production involved in inflammatory response nucleus oligosaccharide binding trans-Golgi network	GO:0005576 GO:0005615 GO:0005634 GO:0005764 GO:0005770 GO:0005802 GO:0005975 GO:0008061 GO:0012505 GO:0016020 GO:0043202 GO:0045087 GO:0070062 GO:0070492 GO:1900016
GL_000197	C-type lectin domain family 7 member A	Q9BXN2	Homo sapiens	9606	(1->3)-beta-D-glucan binding MHC protein binding T cell activation antifungal innate immune response carbohydrate binding carbohydrate mediated signaling cell activation cell recognition cell surface cellular response to molecule of fungal origin cytoplasm defense response to protozoan detection of fungus detection of molecule of fungal origin detection of yeast identical protein binding inflammatory response membrane metal ion binding pattern recognition receptor activity phagocytosis, recognition plasma membrane positive regulation of DNA-binding transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of T-helper 17 type immune response positive regulation of calcium-mediated signaling positive regulation of canonical NF-kappaB signal transduction positive regulation of cell maturation positive regulation of cell migration positive regulation of cell population proliferation positive regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of cytokine production involved in inflammatory response positive regulation of dendritic cell cytokine production positive regulation of gene expression positive regulation of interleukin-1 beta production positive regulation of interleukin-10 production positive regulation of interleukin-12 production positive regulation of interleukin-2 production positive regulation of interleukin-23 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of killing of cells of another organism positive regulation of lymphocyte activation positive regulation of monocyte chemotactic protein-1 production positive regulation of nitric oxide biosynthetic process positive regulation of phagocytosis positive regulation of protein-containing complex assembly positive regulation of respiratory burst positive regulation of superoxide anion generation positive regulation of tumor necrosis factor production positive regulation of type II interferon production positive regulation of wound healing regulation of calcineurin-NFAT signaling cascade regulation of canonical NF-kappaB signal transduction response to yeast stimulatory C-type lectin receptor signaling pathway	GO:0001775 GO:0001872 GO:0001878 GO:0001879 GO:0002223 GO:0002732 GO:0005737 GO:0005886 GO:0006910 GO:0006954 GO:0008037 GO:0008284 GO:0009756 GO:0009986 GO:0010628 GO:0016020 GO:0016046 GO:0030246 GO:0030335 GO:0031334 GO:0032491 GO:0032729 GO:0032731 GO:0032733 GO:0032735 GO:0032743 GO:0032747 GO:0032755 GO:0032757 GO:0032760 GO:0032930 GO:0038187 GO:0042110 GO:0042287 GO:0042802 GO:0042832 GO:0043122 GO:0043123 GO:0043280 GO:0045429 GO:0046872 GO:0050766 GO:0050850 GO:0051091 GO:0051092 GO:0051251 GO:0051712 GO:0060267 GO:0061760 GO:0070884 GO:0071226 GO:0071639 GO:0090303 GO:1900017 GO:1903431 GO:2000318
GL_002069	Regenerating islet-derived protein 4	Q9BYZ8	Homo sapiens	9606	cytoplasm extracellular region heparin binding mannan binding response to bacterium signaling receptor activity	GO:0005576 GO:0005737 GO:0008201 GO:0009617 GO:0038023 GO:2001065
GL_001127	Sialoadhesin	Q9BZZ2	Homo sapiens	9606	carbohydrate binding cell-cell adhesion cell-matrix adhesion clathrin-dependent endocytosis of virus by host cell early endosome extracellular region inflammatory response late endosome membrane negative regulation of type I interferon production plasma membrane virion binding	GO:0005576 GO:0005769 GO:0005770 GO:0005886 GO:0006954 GO:0007160 GO:0016020 GO:0030246 GO:0032480 GO:0046790 GO:0075512 GO:0098609
GL_001218	Alpha-glucosidase	Q9C0Y4	Schizosaccharomyces pombe 972h-	284812	carbohydrate binding extracellular region hydrolase activity, hydrolyzing O-glycosyl compounds maltose alpha-glucosidase activity maltose catabolic process starch alpha-glucosidase activity	GO:0000025 GO:0004553 GO:0005576 GO:0030246 GO:0032450 GO:0044654
GL_001787	Protein NDH-DEPENDENT CYCLIC ELECTRON FLOW 5	Q9C503	Arabidopsis thaliana	3702	carbohydrate binding carbohydrate metabolic process catalytic activity chloroplast chloroplast thylakoid membrane membrane photosynthetic electron transport in photosystem I positive regulation of gene expression	GO:0003824 GO:0005975 GO:0009507 GO:0009535 GO:0009773 GO:0010628 GO:0016020 GO:0030246