GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID	GO Labels ▼	GO IDs
GL_000514	Galectin-9	O00182	Homo sapiens	9606	ERK1 and ERK2 cascade carbohydrate binding cellular response to type II interferon cellular response to virus chemotaxis collagen-containing extracellular matrix cytoplasm cytosol disaccharide binding enzyme binding extracellular space female pregnancy galactose binding galactoside binding inflammatory response maternal process involved in female pregnancy natural killer cell tolerance induction negative regulation of CD4-positive, alpha-beta T cell proliferation negative regulation of activated T cell proliferation negative regulation of chemokine production negative regulation of gene expression negative regulation of mast cell degranulation negative regulation of natural killer cell mediated cytotoxicity negative regulation of tumor necrosis factor production negative regulation of type II interferon production nucleus p38MAPK cascade positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response positive regulation of CD4-positive, alpha-beta T cell proliferation positive regulation of ERK1 and ERK2 cascade positive regulation of NF-kappaB transcription factor activity positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell positive regulation of activated T cell autonomous cell death positive regulation of canonical NF-kappaB signal transduction positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway positive regulation of dendritic cell apoptotic process positive regulation of dendritic cell chemotaxis positive regulation of dendritic cell differentiation positive regulation of gene expression positive regulation of interleukin-1 beta production positive regulation of interleukin-10 production positive regulation of interleukin-12 production positive regulation of interleukin-13 production positive regulation of interleukin-4 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of monocyte chemotactic protein-1 production positive regulation of non-canonical NF-kappaB signal transduction positive regulation of transforming growth factor beta production positive regulation of tumor necrosis factor production positive regulation of type II interferon production positive regulation of viral entry into host cell response to interleukin-1 response to lipopolysaccharide	GO:0002519 GO:0005534 GO:0005615 GO:0005634 GO:0005737 GO:0005829 GO:0006935 GO:0006954 GO:0007565 GO:0010628 GO:0010629 GO:0016936 GO:0019899 GO:0030246 GO:0032496 GO:0032682 GO:0032689 GO:0032720 GO:0032729 GO:0032731 GO:0032733 GO:0032735 GO:0032736 GO:0032753 GO:0032755 GO:0032757 GO:0032760 GO:0032834 GO:0038066 GO:0043123 GO:0043305 GO:0045953 GO:0046007 GO:0046598 GO:0048030 GO:0051092 GO:0060135 GO:0062023 GO:0070241 GO:0070371 GO:0070374 GO:0070555 GO:0071346 GO:0071636 GO:0071639 GO:0098586 GO:1901224 GO:2000510 GO:2000562 GO:2000563 GO:2000670 GO:2001190 GO:2001200 GO:2001269
GL_000995	Protein OS-9 homolog	Q8GWH3	Arabidopsis thaliana	3702	ERAD pathway carbohydrate binding endoplasmic reticulum endoplasmic reticulum unfolded protein response plastid response to salt stress ubiquitin-dependent ERAD pathway	GO:0005783 GO:0009536 GO:0009651 GO:0030246 GO:0030433 GO:0030968 GO:0036503
GL_000303	Cell migration-inducing and hyaluronan-binding protein	Q8BI06	Mus musculus	10090	ER retention sequence binding carbohydrate binding clathrin heavy chain binding clathrin-coated endocytic vesicle clathrin-coated pit clathrin-coated vesicle membrane cytoplasm endoplasmic reticulum extracellular region fibrillar center hyaluronan catabolic process hyaluronan metabolic process hyaluronic acid binding hyalurononglucosaminidase activity nuclear membrane plasma membrane positive regulation of cell migration positive regulation of peptidyl-threonine phosphorylation positive regulation of protein kinase C activity positive regulation of protein targeting to membrane positive regulation of release of sequestered calcium ion into cytosol sensory perception of sound	GO:0001650 GO:0004415 GO:0005540 GO:0005576 GO:0005737 GO:0005783 GO:0005886 GO:0005905 GO:0007605 GO:0010800 GO:0030212 GO:0030214 GO:0030246 GO:0030335 GO:0030665 GO:0031965 GO:0032050 GO:0045334 GO:0046923 GO:0051281 GO:0090314 GO:1900020
GL_000304	Cell migration-inducing and hyaluronan-binding protein	Q8WUJ3	Homo sapiens	9606	ER retention sequence binding carbohydrate binding clathrin heavy chain binding clathrin-coated endocytic vesicle clathrin-coated pit clathrin-coated vesicle membrane cytoplasm endoplasmic reticulum extracellular region fibrillar center hyaluronan biosynthetic process hyaluronan catabolic process hyaluronic acid binding hyalurononglucosaminidase activity nuclear membrane plasma membrane positive regulation of cell migration positive regulation of peptidyl-threonine phosphorylation positive regulation of protein kinase C activity positive regulation of protein targeting to membrane positive regulation of release of sequestered calcium ion into cytosol sensory perception of sound	GO:0001650 GO:0004415 GO:0005540 GO:0005576 GO:0005737 GO:0005783 GO:0005886 GO:0005905 GO:0007605 GO:0010800 GO:0030213 GO:0030214 GO:0030246 GO:0030335 GO:0030665 GO:0031965 GO:0032050 GO:0045334 GO:0046923 GO:0051281 GO:0090314 GO:1900020
GL_001465	ER membrane protein complex subunit 7	Q9NPA0	Homo sapiens	9606	EMC complex carbohydrate binding endoplasmic reticulum membrane membrane protein insertion into ER membrane by stop-transfer membrane-anchor sequence tail-anchored membrane protein insertion into ER membrane	GO:0005789 GO:0016020 GO:0030246 GO:0045050 GO:0071816 GO:0072546
GL_001467	ER membrane protein complex subunit 7	A5PJA8	Bos taurus	9913	EMC complex carbohydrate binding endoplasmic reticulum membrane membrane protein insertion into ER membrane by stop-transfer membrane-anchor sequence tail-anchored membrane protein insertion into ER membrane	GO:0005789 GO:0016020 GO:0030246 GO:0045050 GO:0071816 GO:0072546
GL_001469	ER membrane protein complex subunit 7	Q5TYV0	Danio rerio	7955	EMC complex carbohydrate binding endoplasmic reticulum membrane membrane protein insertion into ER membrane by stop-transfer membrane-anchor sequence tail-anchored membrane protein insertion into ER membrane	GO:0005789 GO:0016020 GO:0030246 GO:0045050 GO:0071816 GO:0072546
GL_001466	ER membrane protein complex subunit 7	Q4R5V2	Macaca fascicularis	9541	EMC complex carbohydrate binding endoplasmic reticulum membrane membrane protein insertion into ER membrane by stop-transfer membrane-anchor sequence tail-anchored membrane protein insertion into ER membrane	GO:0005789 GO:0016020 GO:0030246 GO:0045050 GO:0071816 GO:0072546
GL_001468	ER membrane protein complex subunit 7	Q9EP72	Mus musculus	10090	EMC complex carbohydrate binding endoplasmic reticulum membrane membrane membrane insertase activity protein insertion into ER membrane by stop-transfer membrane-anchor sequence tail-anchored membrane protein insertion into ER membrane	GO:0005789 GO:0016020 GO:0030246 GO:0032977 GO:0045050 GO:0071816 GO:0072546
GL_001852	Transcriptional regulator LsrR	P76141	Escherichia coli K-12	83333	DNA-templated transcription carbohydrate binding cis-regulatory region sequence-specific DNA binding cytosol identical protein binding regulation of DNA-templated transcription initiation response to heat	GO:0000987 GO:0005829 GO:0006351 GO:0009408 GO:0030246 GO:0042802 GO:2000142