GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin ▼	Lectin Name	UniProt ID	Monosaccharide Specificities	Species	Taxonomy ID	GO Labels	GO IDs
GL_000313	Chitinase-3-like protein 1	Q9WTV1		Rattus norvegicus	10116	activation of NF-kappaB-inducing kinase activity apoptotic process carbohydrate binding carbohydrate metabolic process cellular response to interleukin-1 cellular response to tumor necrosis factor chitin binding chitin catabolic process cytoplasm endoplasmic reticulum extracellular region extracellular space inflammatory response lung development perinuclear region of cytoplasm positive regulation of ERK1 and ERK2 cascade positive regulation of angiogenesis positive regulation of interleukin-8 production positive regulation of peptidyl-threonine phosphorylation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction response to interleukin-1 response to interleukin-6 response to mechanical stimulus response to tumor necrosis factor	GO:0005576 GO:0005615 GO:0005737 GO:0005783 GO:0005975 GO:0006032 GO:0006915 GO:0006954 GO:0007250 GO:0008061 GO:0009612 GO:0010800 GO:0030246 GO:0030324 GO:0032757 GO:0034612 GO:0045766 GO:0048471 GO:0051897 GO:0070374 GO:0070555 GO:0070741 GO:0071347 GO:0071356
GL_000312	Chitinase-3-like protein 1	Q7YS85		Bubalus bubalis	89462	activation of NF-kappaB-inducing kinase activity apoptotic process carbohydrate binding carbohydrate metabolic process cellular response to tumor necrosis factor chitin binding cytoplasm endoplasmic reticulum extracellular space inflammatory response lung development perinuclear region of cytoplasm positive regulation of ERK1 and ERK2 cascade positive regulation of angiogenesis positive regulation of interleukin-8 production positive regulation of peptidyl-threonine phosphorylation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction response to interleukin-1 response to interleukin-6 response to mechanical stimulus response to tumor necrosis factor	GO:0005615 GO:0005737 GO:0005783 GO:0005975 GO:0006915 GO:0006954 GO:0007250 GO:0008061 GO:0009612 GO:0010800 GO:0030246 GO:0030324 GO:0032757 GO:0034612 GO:0045766 GO:0048471 GO:0051897 GO:0070374 GO:0070555 GO:0070741 GO:0071356
GL_000311	Chitinase-3-like protein 1	P30922		Bos taurus	9913	activation of NF-kappaB-inducing kinase activity apoptotic process carbohydrate binding carbohydrate metabolic process cellular response to tumor necrosis factor chitin binding chitin catabolic process cytoplasm endoplasmic reticulum extracellular region extracellular space inflammatory response lung development perinuclear region of cytoplasm positive regulation of ERK1 and ERK2 cascade positive regulation of angiogenesis positive regulation of interleukin-8 production positive regulation of peptidyl-threonine phosphorylation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction response to interleukin-1 response to interleukin-6 response to mechanical stimulus response to tumor necrosis factor	GO:0005576 GO:0005615 GO:0005737 GO:0005783 GO:0005975 GO:0006032 GO:0006915 GO:0006954 GO:0007250 GO:0008061 GO:0009612 GO:0010800 GO:0030246 GO:0030324 GO:0032757 GO:0034612 GO:0045766 GO:0048471 GO:0051897 GO:0070374 GO:0070555 GO:0070741 GO:0071356
GL_000310	Chitinase-3-like protein 1	Q29411		Sus scrofa	9823	activation of NF-kappaB-inducing kinase activity apoptotic process carbohydrate binding carbohydrate metabolic process cellular response to tumor necrosis factor chitin binding chitin catabolic process cytoplasm endoplasmic reticulum extracellular region extracellular space inflammatory response lung development perinuclear region of cytoplasm positive regulation of ERK1 and ERK2 cascade positive regulation of angiogenesis positive regulation of interleukin-8 production positive regulation of peptidyl-threonine phosphorylation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction response to interleukin-1 response to interleukin-6 response to mechanical stimulus response to tumor necrosis factor	GO:0005576 GO:0005615 GO:0005737 GO:0005783 GO:0005975 GO:0006032 GO:0006915 GO:0006954 GO:0007250 GO:0008061 GO:0009612 GO:0010800 GO:0030246 GO:0030324 GO:0032757 GO:0034612 GO:0045766 GO:0048471 GO:0051897 GO:0070374 GO:0070555 GO:0070741 GO:0071356
GL_000309	Chitinase-3-like protein 1	P36222		Homo sapiens	9606	activation of NF-kappaB-inducing kinase activity apoptotic process carbohydrate binding carbohydrate metabolic process cartilage development cellular response to tumor necrosis factor chitin binding chitin catabolic process cytoplasm endoplasmic reticulum extracellular exosome extracellular matrix extracellular matrix structural constituent extracellular region extracellular space inflammatory response lung development perinuclear region of cytoplasm positive regulation of ERK1 and ERK2 cascade positive regulation of angiogenesis positive regulation of interleukin-8 production positive regulation of peptidyl-threonine phosphorylation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction response to interleukin-1 response to interleukin-6 response to mechanical stimulus response to tumor necrosis factor specific granule lumen	GO:0005201 GO:0005576 GO:0005615 GO:0005737 GO:0005783 GO:0005975 GO:0006032 GO:0006915 GO:0006954 GO:0007250 GO:0008061 GO:0009612 GO:0010800 GO:0030246 GO:0030324 GO:0031012 GO:0032757 GO:0034612 GO:0035580 GO:0045766 GO:0048471 GO:0051216 GO:0051897 GO:0070062 GO:0070374 GO:0070555 GO:0070741 GO:0071356
GL_000308	Chitin-binding lectin 1	Q9S8M0	GlcNAc	Solanum tuberosum	4113	carbohydrate binding chitin binding defense response	GO:0006952 GO:0008061 GO:0030246
GL_000307	Chitin-binding lectin	P81859		Viscum album	3972	carbohydrate binding chitin binding	GO:0008061 GO:0030246
GL_000306	Cell surface hyaluronidase	A3KPQ7		Danio rerio	7955	angiogenesis atrioventricular valve formation calcium ion binding carbohydrate binding cardiac muscle tissue morphogenesis cell migration involved in heart formation cell migration to the midline involved in heart development embryonic heart tube morphogenesis endocardial cushion development heart looping hyaluronan catabolic process hyalurononglucosaminidase activity muscle attachment muscle tissue morphogenesis plasma membrane positive regulation of extracellular matrix assembly positive regulation of vascular endothelial growth factor signaling pathway regulation of Wnt signaling pathway regulation of sprouting angiogenesis	GO:0001525 GO:0001947 GO:0003143 GO:0003190 GO:0003197 GO:0003318 GO:0004415 GO:0005509 GO:0005886 GO:0016203 GO:0030111 GO:0030214 GO:0030246 GO:0055008 GO:0060415 GO:0060974 GO:1900748 GO:1901203 GO:1903670
GL_000305	Cell surface hyaluronidase	Q5FWI3		Mus musculus	10090	angiogenesis calcium ion binding carbohydrate binding cytosol hyaluronan catabolic process hyalurononglucosaminidase activity intracellular membrane-bounded organelle nucleolus plasma membrane regulation of sprouting angiogenesis	GO:0001525 GO:0004415 GO:0005509 GO:0005730 GO:0005829 GO:0005886 GO:0030214 GO:0030246 GO:0043231 GO:1903670
GL_000304	Cell migration-inducing and hyaluronan-binding protein	Q8WUJ3		Homo sapiens	9606	ER retention sequence binding carbohydrate binding clathrin heavy chain binding clathrin-coated endocytic vesicle clathrin-coated pit clathrin-coated vesicle membrane cytoplasm endoplasmic reticulum extracellular region fibrillar center hyaluronan biosynthetic process hyaluronan catabolic process hyaluronic acid binding hyalurononglucosaminidase activity nuclear membrane plasma membrane positive regulation of cell migration positive regulation of peptidyl-threonine phosphorylation positive regulation of protein kinase C activity positive regulation of protein targeting to membrane positive regulation of release of sequestered calcium ion into cytosol sensory perception of sound	GO:0001650 GO:0004415 GO:0005540 GO:0005576 GO:0005737 GO:0005783 GO:0005886 GO:0005905 GO:0007605 GO:0010800 GO:0030213 GO:0030214 GO:0030246 GO:0030335 GO:0030665 GO:0031965 GO:0032050 GO:0045334 GO:0046923 GO:0051281 GO:0090314 GO:1900020