GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▲	GO Labels	GO IDs
GL_002022	Intelectin-1	Q8WWA0	Homo sapiens	9606	brush border membrane calcium ion binding extracellular exosome extracellular region extracellular space identical protein binding membrane raft oligosaccharide binding positive regulation of glucose import positive regulation of protein phosphorylation protein homotrimerization receptor complex response to nematode side of membrane	GO:0001934 GO:0005509 GO:0005576 GO:0005615 GO:0009624 GO:0031526 GO:0042802 GO:0043235 GO:0045121 GO:0046326 GO:0070062 GO:0070207 GO:0070492 GO:0098552
GL_000190	C-type lectin domain family 5 member A	Q9NY25	Homo sapiens	9606	carbohydrate binding cell surface cellular defense response cytosol innate immune response myeloid cell differentiation negative regulation of apoptotic process negative regulation of myeloid cell apoptotic process osteoblast development plasma membrane positive regulation of cytokine production signal transduction specific granule membrane tertiary granule membrane virus receptor activity	GO:0001618 GO:0001819 GO:0002076 GO:0005829 GO:0005886 GO:0006968 GO:0007165 GO:0009986 GO:0030099 GO:0030246 GO:0033033 GO:0035579 GO:0043066 GO:0045087 GO:0070821
GL_002053	Protein ERGIC-53	P49257	Homo sapiens	9606	COPII-coated ER to Golgi transport vesicle ER to Golgi transport vesicle membrane Golgi membrane Golgi organization blood coagulation collagen-containing extracellular matrix endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum organization endoplasmic reticulum to Golgi vesicle-mediated transport endoplasmic reticulum-Golgi intermediate compartment endoplasmic reticulum-Golgi intermediate compartment membrane extracellular exosome mannose binding membrane metal ion binding negative regulation of protein targeting to mitochondrion positive regulation of organelle organization protein folding protein transport sarcomere unfolded protein binding	GO:0000139 GO:0005537 GO:0005783 GO:0005789 GO:0005793 GO:0006457 GO:0006888 GO:0007029 GO:0007030 GO:0007596 GO:0010638 GO:0012507 GO:0015031 GO:0016020 GO:0030017 GO:0030134 GO:0033116 GO:0046872 GO:0051082 GO:0062023 GO:0070062 GO:1903215
GL_002357	Myelin protein P0	P25189	Homo sapiens	9606	cell aggregation cell-cell adhesion via plasma-membrane adhesion molecules chemical synaptic transmission myelin sheath myelination plasma membrane structural molecule activity synapse	GO:0005198 GO:0005886 GO:0007268 GO:0042552 GO:0043209 GO:0045202 GO:0098742 GO:0098743
GL_002057	Protein ERGIC-53-like	Q9HAT1	Homo sapiens	9606	COPII-coated ER to Golgi transport vesicle Golgi membrane collagen-containing extracellular matrix endoplasmic reticulum membrane endoplasmic reticulum to Golgi vesicle-mediated transport endoplasmic reticulum-Golgi intermediate compartment endoplasmic reticulum-Golgi intermediate compartment membrane mannose binding	GO:0000139 GO:0005537 GO:0005789 GO:0005793 GO:0006888 GO:0030134 GO:0033116 GO:0062023
GL_000071	Attractin	O75882	Homo sapiens	9606	Golgi apparatus carbohydrate binding cerebellum development extracellular exosome extracellular space inflammatory response myelination pigmentation plasma membrane regulation of multicellular organism growth signaling receptor activity	GO:0005615 GO:0005794 GO:0005886 GO:0006954 GO:0021549 GO:0030246 GO:0038023 GO:0040014 GO:0042552 GO:0043473 GO:0070062
GL_000517	Galectin-9C	Q6DKI2	Homo sapiens	9606	carbohydrate binding cytosol galactoside binding negative regulation of CD4-positive, alpha-beta T cell proliferation negative regulation of type II interferon production nucleus positive regulation of gene expression	GO:0005634 GO:0005829 GO:0010628 GO:0016936 GO:0030246 GO:0032689 GO:2000562
GL_002428	Sialic acid-binding Ig-like lectin 15	Q6ZMC9	Homo sapiens	9606	plasma membrane protein-containing complex regulation of actin cytoskeleton organization regulation of bone resorption regulation of osteoclast development	GO:0005886 GO:0032956 GO:0032991 GO:0045124 GO:2001204
GL_000874	Placental protein 13-like	Q8TCE9	Homo sapiens	9606	apoptotic process carbohydrate binding nucleoplasm	GO:0005654 GO:0006915 GO:0030246
GL_000980	Protein FAM3D	Q96BQ1	Homo sapiens	9606	carbohydrate binding cytokine activity extracellular region extracellular space negative regulation of insulin secretion	GO:0005125 GO:0005576 GO:0005615 GO:0030246 GO:0046676