GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▼	GO Labels	GO IDs
GL_000636	Killer cell lectin-like receptor subfamily I member 2	Q5DT37	Rattus norvegicus	10116	carbohydrate binding external side of plasma membrane plasma membrane positive regulation of natural killer cell mediated cytotoxicity stimulatory C-type lectin receptor signaling pathway transmembrane signaling receptor activity	GO:0002223 GO:0004888 GO:0005886 GO:0009897 GO:0030246 GO:0045954
GL_002030	L-selectin	P30836	Rattus norvegicus	10116	calcium ion binding calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules cell adhesion molecule binding cell surface external side of plasma membrane extracellular space glycolipid binding heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte tethering or rolling oligosaccharide binding plasma membrane positive regulation of neutrophil chemotaxis protease binding regulation of apoptotic process response to ATP response to cytokine response to hyperoxia response to linoleic acid response to oleic acid sialic acid binding	GO:0002020 GO:0005509 GO:0005615 GO:0005886 GO:0007157 GO:0009897 GO:0009986 GO:0016339 GO:0033198 GO:0033691 GO:0034097 GO:0034201 GO:0042981 GO:0050839 GO:0050901 GO:0051861 GO:0055093 GO:0070492 GO:0070543 GO:0090023
GL_000798	N-acetylgalactosaminyltransferase 7	Q9R0C5	Rattus norvegicus	10116	Golgi apparatus Golgi membrane carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0030246 GO:0046872
GL_001831	Sclerostin	Q99P67	Rattus norvegicus	10116	BMP binding BMP signaling pathway DNA-binding transcription factor binding Golgi apparatus canonical Wnt signaling pathway carbohydrate binding cellular response to parathyroid hormone stimulus extracellular space heparin binding localization molecular function inhibitor activity negative regulation of BMP signaling pathway negative regulation of Wnt signaling pathway negative regulation of canonical Wnt signaling pathway negative regulation of ossification negative regulation of protein-containing complex assembly ossification positive regulation of DNA-templated transcription protein-containing complex response to mechanical stimulus	GO:0001503 GO:0005615 GO:0005794 GO:0008201 GO:0009612 GO:0030178 GO:0030246 GO:0030279 GO:0030509 GO:0030514 GO:0031333 GO:0032991 GO:0036122 GO:0045893 GO:0051179 GO:0060070 GO:0071374 GO:0090090 GO:0140297 GO:0140678
GL_001411	Collagen alpha-1(IX) chain (Fragment)	P20850	Rattus norvegicus	10116	bone morphogenesis carbohydrate binding cartilage development chondrocyte differentiation chondrocyte proliferation collagen type IX trimer extracellular region growth plate cartilage development metal ion binding protein homodimerization activity skeletal system development tissue homeostasis	GO:0001501 GO:0001894 GO:0002062 GO:0003417 GO:0005576 GO:0005594 GO:0030246 GO:0035988 GO:0042803 GO:0046872 GO:0051216 GO:0060349
GL_000181	C-type lectin domain family 4 member E	Q67EQ1	Rattus norvegicus	10116	Fc-gamma receptor signaling pathway T cell differentiation involved in immune response antifungal innate immune response calcium ion binding carbohydrate binding cell projection defense response to bacterium external side of plasma membrane glycolipid binding immune response innate immune response membrane pattern recognition receptor activity pattern recognition receptor signaling pathway phagocytic cup phagocytic vesicle membrane plasma membrane positive regulation of cytokine production signaling receptor activity	GO:0001819 GO:0001891 GO:0002221 GO:0002292 GO:0005509 GO:0005886 GO:0006955 GO:0009897 GO:0016020 GO:0030246 GO:0030670 GO:0038023 GO:0038094 GO:0038187 GO:0042742 GO:0042995 GO:0045087 GO:0051861 GO:0061760
GL_000052	Aggrecan core protein	P07897	Rattus norvegicus	10116	GABA-ergic synapse basement membrane calcium ion binding carbohydrate binding cartilage condensation cell adhesion cellular response to growth factor stimulus central nervous system development chondroblast differentiation chondrocyte development collagen fibril organization extracellular matrix extracellular space glial cell differentiation glutamatergic synapse heart development hyaluronic acid binding negative regulation of cell migration neuronal cell body ossification perineuronal net perisynaptic extracellular matrix positive regulation of neuroblast proliferation proteoglycan biosynthetic process response to acidic pH response to glucose response to gravity response to mechanical stimulus response to organic cyclic compound response to xenobiotic stimulus skeletal system development spinal cord development synapse	GO:0001501 GO:0001502 GO:0001503 GO:0002052 GO:0002063 GO:0005509 GO:0005540 GO:0005604 GO:0005615 GO:0007155 GO:0007417 GO:0007507 GO:0009410 GO:0009612 GO:0009629 GO:0009749 GO:0010001 GO:0010447 GO:0014070 GO:0021510 GO:0030166 GO:0030199 GO:0030246 GO:0030336 GO:0031012 GO:0043025 GO:0045202 GO:0060591 GO:0071363 GO:0072534 GO:0098966 GO:0098978 GO:0098982
GL_001457	Endomucin	Q6AY82	Rattus norvegicus	10116	angiogenesis carbohydrate binding cell-cell adhesion hematopoietic stem cell homeostasis plasma membrane regulation of cell adhesion	GO:0001525 GO:0005886 GO:0030155 GO:0030246 GO:0061484 GO:0098609
GL_001640	Glycogen phosphorylase, brain form (Fragment)	P53534	Rattus norvegicus	10116	SHG alpha-glucan phosphorylase activity axon carbohydrate binding cytoplasm glycogen catabolic process glycogen metabolic process glycogen phosphorylase activity identical protein binding linear malto-oligosaccharide phosphorylase activity organic cyclic compound binding pyridoxal phosphate binding	GO:0005737 GO:0005977 GO:0005980 GO:0008184 GO:0030170 GO:0030246 GO:0030424 GO:0042802 GO:0097159 GO:0102250 GO:0102499
GL_001850	Transaldolase	Q9EQS0	Rattus norvegicus	10116	carbohydrate binding carbohydrate metabolic process cytoplasm cytosol fructose 6-phosphate metabolic process glyceraldehyde-3-phosphate metabolic process identical protein binding monosaccharide binding nucleus pentose-phosphate shunt pentose-phosphate shunt, non-oxidative branch transaldolase activity	GO:0004801 GO:0005634 GO:0005737 GO:0005829 GO:0005975 GO:0006002 GO:0006098 GO:0009052 GO:0019682 GO:0030246 GO:0042802 GO:0048029