GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▼	GO Labels	GO IDs
GL_001638	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1	P82808	Rattus norvegicus	10116	UDP-N-acetylglucosamine biosynthetic process UDP-N-acetylglucosamine metabolic process amino acid binding carbohydrate binding carbohydrate derivative binding cellular response to insulin stimulus circadian regulation of gene expression fructose 6-phosphate metabolic process glucosamine biosynthetic process glutamine metabolic process glutamine-fructose-6-phosphate transaminase (isomerizing) activity identical protein binding negative regulation of glycogen biosynthetic process protein N-linked glycosylation response to insulin response to sucrose	GO:0004360 GO:0006002 GO:0006042 GO:0006047 GO:0006048 GO:0006487 GO:0006541 GO:0009744 GO:0016597 GO:0030246 GO:0032868 GO:0032869 GO:0032922 GO:0042802 GO:0045719 GO:0097367
GL_000489	Galectin-2	Q9Z144	Rattus norvegicus	10116	T cell homeostasis carbohydrate binding cell-cell adhesion galactoside binding galectin complex positive regulation of apoptotic process positive regulation of inflammatory response	GO:0016936 GO:0030246 GO:0043029 GO:0043065 GO:0050729 GO:0098609 GO:1990724
GL_001230	Alpha-mannosidase 2	P28494	Rattus norvegicus	10116	Golgi apparatus Golgi medial cisterna Golgi membrane N-glycan processing alpha-mannosidase activity carbohydrate binding cis-Golgi network extracellular space hydrolase activity hydrolase activity, hydrolyzing N-glycosyl compounds identical protein binding in utero embryonic development liver development lung alveolus development mannose metabolic process mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity mitochondrion organization positive regulation of neurogenesis protein glycosylation protein homodimerization activity respiratory gaseous exchange by respiratory system retina morphogenesis in camera-type eye vacuole organization zinc ion binding	GO:0000139 GO:0001701 GO:0001889 GO:0004559 GO:0004572 GO:0005615 GO:0005794 GO:0005797 GO:0005801 GO:0006013 GO:0006486 GO:0006491 GO:0007005 GO:0007033 GO:0007585 GO:0008270 GO:0015923 GO:0016787 GO:0016799 GO:0030246 GO:0042802 GO:0042803 GO:0048286 GO:0050769 GO:0060042
GL_002068	Regenerating islet-derived protein 3-gamma	P42854	Rattus norvegicus	10116	MyD88-dependent toll-like receptor signaling pathway acute-phase response antimicrobial humoral immune response mediated by antimicrobial peptide defense response to Gram-negative bacterium defense response to Gram-positive bacterium extracellular space hormone activity metal ion binding negative regulation of inflammatory response negative regulation of inflammatory response to wounding negative regulation of keratinocyte differentiation oligosaccharide binding peptidoglycan binding positive regulation of cell population proliferation positive regulation of detection of glucose positive regulation of keratinocyte proliferation positive regulation of wound healing response to bacterium response to peptide hormone response to symbiotic bacterium secretory granule signaling receptor activity	GO:0002755 GO:0005179 GO:0005615 GO:0006953 GO:0008284 GO:0009609 GO:0009617 GO:0010838 GO:0030141 GO:0038023 GO:0042834 GO:0043434 GO:0045617 GO:0046872 GO:0050728 GO:0050829 GO:0050830 GO:0061844 GO:0070492 GO:0090303 GO:0106015 GO:2000972
GL_002060	Pulmonary surfactant-associated protein D	P35248	Rattus norvegicus	10116	collagen trimer cytoplasm extracellular space identical protein binding innate immune response lipopolysaccharide binding lung alveolus development monosaccharide binding multivesicular body negative regulation of T cell proliferation negative regulation of interleukin-2 production negative regulation of phagocytosis opsonization positive regulation of phagocytosis respiratory gaseous exchange by respiratory system response to glucocorticoid response to growth factor response to hyperoxia surfactant homeostasis	GO:0001530 GO:0005581 GO:0005615 GO:0005737 GO:0005771 GO:0007585 GO:0008228 GO:0032703 GO:0042130 GO:0042802 GO:0043129 GO:0045087 GO:0048029 GO:0048286 GO:0050765 GO:0050766 GO:0051384 GO:0055093 GO:0070848
GL_000160	C-type lectin domain family 2 member D6	A4KWA8	Rattus norvegicus	10116	carbohydrate binding external side of plasma membrane natural killer cell lectin-like receptor binding	GO:0009897 GO:0030246 GO:0046703
GL_000615	Killer cell lectin-like receptor subfamily B member 1B allele A	A4KWA1	Rattus norvegicus	10116	carbohydrate binding cell surface plasma membrane regulation of natural killer cell mediated cytotoxicity signaling receptor activity	GO:0005886 GO:0009986 GO:0030246 GO:0038023 GO:0042269
GL_001867	Transketolase	P50137	Rattus norvegicus	10116	calcium ion binding carbohydrate binding cytosol endoplasmic reticulum membrane glyceraldehyde-3-phosphate biosynthetic process magnesium ion binding monosaccharide binding pentose-phosphate shunt pentose-phosphate shunt, non-oxidative branch peroxisome protein homodimerization activity regulation of growth thiamine pyrophosphate binding transketolase activity xylulose 5-phosphate biosynthetic process	GO:0000287 GO:0004802 GO:0005509 GO:0005777 GO:0005789 GO:0005829 GO:0006098 GO:0009052 GO:0030246 GO:0030976 GO:0040008 GO:0042803 GO:0046166 GO:0048029 GO:1901159
GL_000155	C-type lectin domain family 2 member D-related protein	Q5M9I1	Rattus norvegicus	10116	carbohydrate binding external side of plasma membrane natural killer cell lectin-like receptor binding	GO:0009897 GO:0030246 GO:0046703
GL_001643	Glycogen phosphorylase, muscle form	P09812	Rattus norvegicus	10116	AMP binding SHG alpha-glucan phosphorylase activity carbohydrate binding cytoplasm glycogen catabolic process glycogen metabolic process glycogen phosphorylase activity intracellular calcium ion homeostasis linear malto-oligosaccharide phosphorylase activity organic cyclic compound binding pyridoxal phosphate binding response to cAMP response to hypoxia response to organic substance sarcoplasmic reticulum	GO:0001666 GO:0005737 GO:0005977 GO:0005980 GO:0006874 GO:0008184 GO:0010033 GO:0016208 GO:0016529 GO:0030170 GO:0030246 GO:0051591 GO:0097159 GO:0102250 GO:0102499