GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▲	GO Labels	GO IDs
GL_000883	Polypeptide N-acetylgalactosaminyltransferase 1	Q10472	Homo sapiens	9606	Golgi cisterna membrane Golgi membrane O-glycan processing carbohydrate binding endoplasmic reticulum membrane endoplasmic reticulum-Golgi intermediate compartment membrane extracellular region manganese ion binding membrane perinuclear region of cytoplasm polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation protein O-linked glycosylation via serine protein O-linked glycosylation via threonine viral protein processing	GO:0000139 GO:0004653 GO:0005576 GO:0005789 GO:0006493 GO:0016020 GO:0016266 GO:0018242 GO:0018243 GO:0019082 GO:0030145 GO:0030246 GO:0032580 GO:0033116 GO:0048471
GL_000534	Grifin	A4D1Z8	Homo sapiens	9606	carbohydrate binding	GO:0030246
GL_002386	Trefoil factor 3	Q07654	Homo sapiens	9606	extracellular region extracellular space identical protein binding maintenance of gastrointestinal epithelium regulation of glucose metabolic process secretory granule	GO:0005576 GO:0005615 GO:0010906 GO:0030141 GO:0030277 GO:0042802
GL_000482	Galectin-10	Q05315	Homo sapiens	9606	T cell apoptotic process carbohydrate binding collagen-containing extracellular matrix cysteine-type endopeptidase activity involved in apoptotic process cytosol identical protein binding regulation of T cell anergy regulation of T cell cytokine production regulation of activated T cell proliferation	GO:0002667 GO:0002724 GO:0005829 GO:0030246 GO:0042802 GO:0046006 GO:0062023 GO:0070231 GO:0097153
GL_000176	C-type lectin domain family 4 member C	Q8WTT0	Homo sapiens	9606	adaptive immune response antifungal innate immune response carbohydrate binding external side of plasma membrane ficolin-1-rich granule membrane metal ion binding plasma membrane secretory granule membrane tertiary granule membrane	GO:0002250 GO:0005886 GO:0009897 GO:0030246 GO:0030667 GO:0046872 GO:0061760 GO:0070821 GO:0101003
GL_000914	Polypeptide N-acetylgalactosaminyltransferase 3	Q14435	Homo sapiens	9606	Golgi apparatus Golgi cisterna membrane Golgi membrane O-glycan processing calcium ion binding carbohydrate binding carbohydrate metabolic process extracellular exosome fibroblast growth factor receptor signaling pathway manganese ion binding membrane perinuclear region of cytoplasm polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation protein O-linked glycosylation via serine protein O-linked glycosylation via threonine spermatogenesis	GO:0000139 GO:0004653 GO:0005509 GO:0005794 GO:0005975 GO:0006493 GO:0007283 GO:0008543 GO:0016020 GO:0016266 GO:0018242 GO:0018243 GO:0030145 GO:0030246 GO:0032580 GO:0048471 GO:0070062
GL_000829	NKG2-E type II integral membrane protein	Q07444	Homo sapiens	9606	carbohydrate binding cellular defense response external side of plasma membrane plasma membrane positive regulation of natural killer cell mediated cytotoxicity receptor complex regulation of natural killer cell activation stimulatory C-type lectin receptor signaling pathway transmembrane signaling receptor activity	GO:0002223 GO:0004888 GO:0005886 GO:0006968 GO:0009897 GO:0030246 GO:0032814 GO:0043235 GO:0045954
GL_000972	Protein FAM3B	P58499	Homo sapiens	9606	apoptotic process carbohydrate binding cytokine activity extracellular exosome extracellular region extracellular space insulin secretion	GO:0005125 GO:0005576 GO:0005615 GO:0006915 GO:0030073 GO:0030246 GO:0070062
GL_000187	C-type lectin domain family 4 member G	Q6UXB4	Homo sapiens	9606	T cell mediated immunity alpha-beta T cell proliferation carbohydrate binding carbohydrate derivative binding external side of plasma membrane fructose binding glycosylated region protein binding immature T cell proliferation in thymus immune response mannose binding negative regulation of T cell mediated immunity negative regulation of alpha-beta T cell proliferation negative regulation of immature T cell proliferation in thymus plasma membrane polysaccharide binding positive regulation of viral life cycle viral entry into host cell virus coreceptor activity virus receptor activity	GO:0001618 GO:0002456 GO:0002710 GO:0005537 GO:0005886 GO:0006955 GO:0009897 GO:0030246 GO:0030247 GO:0033080 GO:0033088 GO:0046633 GO:0046642 GO:0046718 GO:0070061 GO:0097367 GO:0120274 GO:0140081 GO:1903902
GL_000877	Polycystin-1-like protein 2	Q7Z442	Homo sapiens	9606	calcium channel activity calcium ion binding carbohydrate binding detection of mechanical stimulus membrane	GO:0005262 GO:0005509 GO:0016020 GO:0030246 GO:0050982