GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▼	GO Labels	GO IDs
GL_000630	Killer cell lectin-like receptor subfamily G member 1	Q64335	Rattus norvegicus	10116	carbohydrate binding innate immune response plasma membrane	GO:0005886 GO:0030246 GO:0045087
GL_002071	Regenerating islet-derived protein 4	Q68AX7	Rattus norvegicus	10116	cytoplasm extracellular region heparin binding mannan binding response to bacterium signaling receptor activity	GO:0005576 GO:0005737 GO:0008201 GO:0009617 GO:0038023 GO:2001065
GL_000894	Polypeptide N-acetylgalactosaminyltransferase 11	Q6P6V1	Rattus norvegicus	10116	Golgi apparatus Golgi membrane Notch binding Notch receptor processing Notch signaling involved in heart development carbohydrate binding cilium assembly determination of left/right symmetry metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation protein O-linked glycosylation via threonine regulation of Notch signaling pathway	GO:0000139 GO:0004653 GO:0005112 GO:0005794 GO:0006493 GO:0007220 GO:0007368 GO:0008593 GO:0018243 GO:0030246 GO:0046872 GO:0060271 GO:0061314
GL_000778	Myelin-associated glycoprotein	P07722	Rattus norvegicus	10116	Schmidt-Lanterman incisure axon regeneration carbohydrate binding cell adhesion cell-cell adhesion via plasma-membrane adhesion molecules cellular response to mechanical stimulus central nervous system myelin formation central nervous system myelination compact myelin ganglioside GT1b binding membrane raft mesaxon myelin sheath myelin sheath adaxonal region myelination negative regulation of axon extension negative regulation of neuron apoptotic process negative regulation of neuron differentiation negative regulation of neuron projection development nervous system development paranode region of axon plasma membrane positive regulation of astrocyte differentiation positive regulation of myelination protein homodimerization activity protein kinase binding sialic acid binding signaling receptor binding transmission of nerve impulse	GO:0005102 GO:0005886 GO:0007155 GO:0007399 GO:0010977 GO:0019226 GO:0019901 GO:0022010 GO:0030246 GO:0030517 GO:0031103 GO:0031643 GO:0032289 GO:0033270 GO:0033691 GO:0035749 GO:0042552 GO:0042803 GO:0043209 GO:0043218 GO:0043220 GO:0043524 GO:0045121 GO:0045665 GO:0048711 GO:0071260 GO:0097453 GO:0098742 GO:1905576
GL_000156	C-type lectin domain family 2 member D11	Q0H8B9	Rattus norvegicus	10116	carbohydrate binding external side of plasma membrane natural killer cell lectin-like receptor binding	GO:0009897 GO:0030246 GO:0046703
GL_000826	NKG2-D type II integral membrane protein	O70215	Rattus norvegicus	10116	MHC class I protein binding MHC class Ib receptor activity adaptive immune response carbohydrate binding cell differentiation cell surface cellular response to lipopolysaccharide defense response to Gram-positive bacterium external side of plasma membrane identical protein binding kinase binding natural killer cell activation natural killer cell mediated cytotoxicity negative regulation of natural killer cell chemotaxis nitric oxide biosynthetic process plasma membrane positive regulation of apoptotic process positive regulation of myeloid dendritic cell activation positive regulation of natural killer cell mediated cytotoxicity positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target positive regulation of nitric oxide biosynthetic process positive regulation of type II interferon production signaling receptor activity stimulatory C-type lectin receptor signaling pathway	GO:0002223 GO:0002250 GO:0002860 GO:0005886 GO:0006809 GO:0009897 GO:0009986 GO:0019900 GO:0030101 GO:0030154 GO:0030246 GO:0030887 GO:0032394 GO:0032729 GO:0038023 GO:0042267 GO:0042288 GO:0042802 GO:0043065 GO:0045429 GO:0045954 GO:0050830 GO:0071222 GO:2000502
GL_000510	Galectin-8	Q62665	Rattus norvegicus	10116	T cell costimulation carbohydrate binding cellular response to virus cytoplasm cytoplasmic vesicle cytosol integrin binding lymphatic endothelial cell migration plasma cell differentiation xenophagy	GO:0002317 GO:0005178 GO:0005737 GO:0005829 GO:0030246 GO:0031295 GO:0031410 GO:0098586 GO:0098792 GO:1904977
GL_000201	C-type lectin domain family 9 member A	D4AD02	Rattus norvegicus	10116	carbohydrate binding cell surface membrane positive regulation of cytokine production receptor-mediated endocytosis	GO:0001819 GO:0006898 GO:0009986 GO:0016020 GO:0030246
GL_001368	Beta-glucuronidase	P06760	Rattus norvegicus	10116	beta-glucuronidase activity carbohydrate binding carbohydrate metabolic process chondroitin sulfate catabolic process extracellular space glucuronoside catabolic process heparan sulfate proteoglycan catabolic process hyaluronan catabolic process hydrolase activity lysosomal lumen lysosome protein domain specific binding signaling receptor binding	GO:0004566 GO:0005102 GO:0005615 GO:0005764 GO:0005975 GO:0016787 GO:0019391 GO:0019904 GO:0030200 GO:0030207 GO:0030214 GO:0030246 GO:0043202
GL_000989	Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1	Q5XIN7	Rattus norvegicus	10116	Golgi membrane O-glycan processing acetylglucosaminyltransferase activity basement membrane organization beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity brain development carbohydrate binding dentate gyrus development gene expression localization of cell manganese ion binding membrane myelination protein O-linked glycosylation protein O-linked mannosylation protein glycosylation protein modification process reactive gliosis sensory perception of sound	GO:0000139 GO:0006486 GO:0006493 GO:0007420 GO:0007605 GO:0008375 GO:0010467 GO:0016020 GO:0016266 GO:0021542 GO:0030145 GO:0030246 GO:0035269 GO:0036211 GO:0042552 GO:0047223 GO:0051674 GO:0071711 GO:0150103