GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▼	GO Labels	GO IDs
GL_000992	Protein OS-9	Q5RKH6	Rattus norvegicus	10116	carbohydrate binding endoplasmic reticulum lumen endoplasmic reticulum unfolded protein response negative regulation of retrograde protein transport, ER to cytosol protease binding protein retention in ER lumen protein targeting protein ubiquitination response to endoplasmic reticulum stress retrograde protein transport, ER to cytosol ubiquitin-dependent ERAD pathway ubiquitin-dependent protein catabolic process	GO:0002020 GO:0005788 GO:0006511 GO:0006605 GO:0006621 GO:0016567 GO:0030246 GO:0030433 GO:0030968 GO:0030970 GO:0034976 GO:1904153
GL_000325	Collectin-12	Q4V885	Rattus norvegicus	10116	carbohydrate binding cellular response to exogenous dsRNA collagen trimer defense response to bacterium immune response low-density lipoprotein particle binding membrane metal ion binding pattern recognition receptor activity phagocytosis, recognition plasma membrane raft organization scavenger receptor activity signaling receptor activity toll-like receptor 3 signaling pathway	GO:0005044 GO:0005581 GO:0006910 GO:0006955 GO:0016020 GO:0030169 GO:0030246 GO:0034138 GO:0038023 GO:0038187 GO:0042742 GO:0044857 GO:0046872 GO:0071360
GL_000387	Ficolin-1	Q9WTS8	Rattus norvegicus	10116	G protein-coupled receptor signaling pathway antigen binding carbohydrate binding carbohydrate derivative binding cell surface pattern recognition receptor signaling pathway collagen trimer collagen-containing extracellular matrix complement activation, lectin pathway extracellular space metal ion binding pattern recognition receptor activity plasma membrane positive regulation of interleukin-8 production signaling receptor binding	GO:0001867 GO:0002752 GO:0003823 GO:0005102 GO:0005581 GO:0005615 GO:0005886 GO:0007186 GO:0030246 GO:0032757 GO:0038187 GO:0046872 GO:0062023 GO:0097367
GL_002038	Lithostathine	P10758	Rattus norvegicus	10116	antimicrobial humoral immune response mediated by antimicrobial peptide basal part of cell cellular response to chemokine cellular response to gastrin dendrite membrane extracellular space gene expression growth cone growth factor activity identical protein binding liver regeneration midgut development molecular function inhibitor activity negative regulation of cell population proliferation neuronal cell body membrane oligosaccharide binding pancreas regeneration peptidoglycan binding perinuclear region of cytoplasm phosphatase binding phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of acinar cell proliferation positive regulation of cell population proliferation positive regulation of dendrite extension positive regulation of gene expression positive regulation of protein phosphorylation positive regulation of type B pancreatic cell proliferation protein phosphatase binding protein-containing complex response to gastrin response to growth hormone-releasing hormone response to hypoxia response to nutrient levels response to organic cyclic compound response to peptide hormone response to water-immersion restraint stress signaling receptor activity signaling receptor binding type B pancreatic cell differentiation zymogen granule	GO:0001666 GO:0001934 GO:0003309 GO:0005102 GO:0005615 GO:0007494 GO:0008083 GO:0008284 GO:0008285 GO:0010467 GO:0010628 GO:0014070 GO:0019902 GO:0019903 GO:0030426 GO:0031667 GO:0032590 GO:0032809 GO:0032991 GO:0038023 GO:0042588 GO:0042802 GO:0042834 GO:0043434 GO:0043491 GO:0045178 GO:0048471 GO:0061844 GO:0070492 GO:0097421 GO:0140678 GO:1903861 GO:1904692 GO:1904699 GO:1990785 GO:1990798 GO:1990864 GO:1990867 GO:1990869 GO:1990878
GL_000502	Galectin-4	P38552	Rattus norvegicus	10116	antibacterial peptide biosynthetic process carbohydrate binding defense response to bacterium extracellular space galactoside binding	GO:0002780 GO:0005615 GO:0016936 GO:0030246 GO:0042742
GL_000612	Killer cell lectin-like receptor subfamily B member 1	Q0ZUP0	Rattus norvegicus	10116	carbohydrate binding cell surface plasma membrane regulation of natural killer cell mediated cytotoxicity signaling receptor activity	GO:0005886 GO:0009986 GO:0030246 GO:0038023 GO:0042269
GL_001179	Zymogen granule membrane protein 16	Q8CJD3	Rattus norvegicus	10116	Golgi lumen carbohydrate binding collagen-containing extracellular matrix defense response to Gram-positive bacterium extracellular space mucus layer peptidoglycan binding protein transport suppression of symbiont entry into host zymogen granule membrane	GO:0005615 GO:0005796 GO:0015031 GO:0030246 GO:0042589 GO:0042834 GO:0050830 GO:0052373 GO:0062023 GO:0070701
GL_000024	Adhesion G protein-coupled receptor L3	Q9Z173	Rattus norvegicus	10116	G protein-coupled receptor activity Schaffer collateral - CA1 synapse adenylate cyclase-activating G protein-coupled receptor signaling pathway axon calcium ion binding carbohydrate binding cell surface receptor signaling pathway cell-cell adhesion via plasma-membrane adhesion molecules cell-cell junction glutamatergic synapse locomotion involved in locomotory behavior maintenance of postsynaptic specialization structure neuron migration plasma membrane positive regulation of synapse assembly postsynaptic membrane response to cocaine synapse assembly synapse organization	GO:0001764 GO:0004930 GO:0005509 GO:0005886 GO:0005911 GO:0007166 GO:0007189 GO:0007416 GO:0030246 GO:0030424 GO:0031987 GO:0042220 GO:0045211 GO:0050808 GO:0051965 GO:0098685 GO:0098742 GO:0098880 GO:0098978
GL_001985	Asialoglycoprotein receptor 2	P08290	Rattus norvegicus	10116	bone mineralization endocytosis endoplasmic reticulum quality control compartment external side of plasma membrane fucose binding glycoprotein metabolic process lipid homeostasis mannose binding perinuclear region of cytoplasm regulation of protein stability	GO:0005537 GO:0006897 GO:0009100 GO:0009897 GO:0030282 GO:0031647 GO:0042806 GO:0044322 GO:0048471 GO:0055088
GL_000179	C-type lectin domain family 4 member D	Q69FH1	Rattus norvegicus	10116	Fc-gamma receptor signaling pathway T cell differentiation involved in immune response adaptive immune response antifungal innate immune response carbohydrate binding defense response to bacterium external side of plasma membrane immunoglobulin receptor binding innate immune response mannose binding metal ion binding pattern recognition receptor activity plasma membrane positive regulation of canonical NF-kappaB signal transduction positive regulation of myeloid dendritic cell activation	GO:0002250 GO:0002292 GO:0005537 GO:0005886 GO:0009897 GO:0030246 GO:0030887 GO:0034987 GO:0038094 GO:0038187 GO:0042742 GO:0043123 GO:0045087 GO:0046872 GO:0061760