GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▲	GO Labels	GO IDs
GL_001111	Sialic acid-binding Ig-like lectin 10	Q96LC7	Homo sapiens	9606	SH2 domain binding adaptive immune response carbohydrate binding cell adhesion extracellular region innate immune response negative regulation of inflammatory response to wounding phosphatase binding plasma membrane sialic acid binding	GO:0002250 GO:0005576 GO:0005886 GO:0007155 GO:0019902 GO:0030246 GO:0033691 GO:0042169 GO:0045087 GO:0106015
GL_000169	C-type lectin domain family 3 member A	O75596	Homo sapiens	9606	carbohydrate binding extracellular space ossification skeletal system development	GO:0001501 GO:0001503 GO:0005615 GO:0030246
GL_000373	F-box only protein 2	Q9UK22	Homo sapiens	9606	SCF ubiquitin ligase complex SCF-dependent proteasomal ubiquitin-dependent protein catabolic process amyloid-beta binding carbohydrate binding cytoplasm cytosol denatured protein binding dendritic spine endoplasmic reticulum extrinsic component of postsynaptic membrane glutamatergic synapse glycoprotein catabolic process negative regulation of cell population proliferation protein modification process protein ubiquitination proteolysis regulation of protein catabolic process at postsynapse, modulating synaptic transmission regulation of protein ubiquitination ubiquitin-dependent ERAD pathway ubiquitin-protein transferase activity	GO:0001540 GO:0004842 GO:0005737 GO:0005783 GO:0005829 GO:0006508 GO:0006516 GO:0008285 GO:0016567 GO:0019005 GO:0030246 GO:0030433 GO:0031146 GO:0031249 GO:0031396 GO:0036211 GO:0043197 GO:0098890 GO:0098978 GO:0099576
GL_000907	Polypeptide N-acetylgalactosaminyltransferase 17	Q6IS24	Homo sapiens	9606	Golgi apparatus Golgi membrane carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0030246 GO:0046872
GL_001118	Sialic acid-binding Ig-like lectin 16	A6NMB1	Homo sapiens	9606	carbohydrate binding cell adhesion plasma membrane positive regulation of defense response to bacterium positive regulation of interleukin-6 production sialic acid binding	GO:0005886 GO:0007155 GO:0030246 GO:0032755 GO:0033691 GO:1900426
GL_001231	Alpha-mannosidase 2	Q16706	Homo sapiens	9606	Golgi medial cisterna Golgi membrane N-glycan processing alpha-mannosidase activity carbohydrate binding cis-Golgi network extracellular exosome hydrolase activity, hydrolyzing N-glycosyl compounds in utero embryonic development liver development lung alveolus development mannose metabolic process mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity membrane metal ion binding mitochondrion organization positive regulation of neurogenesis protein glycosylation protein homodimerization activity respiratory gaseous exchange by respiratory system retina morphogenesis in camera-type eye vacuole organization viral protein processing	GO:0000139 GO:0001701 GO:0001889 GO:0004559 GO:0004572 GO:0005797 GO:0005801 GO:0006013 GO:0006486 GO:0006491 GO:0007005 GO:0007033 GO:0007585 GO:0016020 GO:0016799 GO:0019082 GO:0030246 GO:0042803 GO:0046872 GO:0048286 GO:0050769 GO:0060042 GO:0070062
GL_000139	C-type lectin domain family 10 member A	Q8IUN9	Homo sapiens	9606	adaptive immune response carbohydrate binding endocytosis external side of plasma membrane fucose binding innate immune response mannose binding plasma membrane	GO:0002250 GO:0005537 GO:0005886 GO:0006897 GO:0009897 GO:0030246 GO:0042806 GO:0045087
GL_002302	C-reactive protein	P02741	Homo sapiens	9606	acute-phase response calcium ion binding choline binding complement component C1q complex binding defense response to Gram-positive bacterium extracellular region extracellular space identical protein binding inflammatory response innate immune response low-density lipoprotein particle binding low-density lipoprotein particle receptor binding negative regulation of lipid storage negative regulation of macrophage derived foam cell differentiation negative regulation of mononuclear cell proliferation opsonization positive regulation of gene expression positive regulation of superoxide anion generation regulation of interleukin-8 production vasoconstriction	GO:0001849 GO:0005509 GO:0005576 GO:0005615 GO:0006953 GO:0006954 GO:0008228 GO:0010628 GO:0010745 GO:0010888 GO:0030169 GO:0032677 GO:0032930 GO:0032945 GO:0033265 GO:0042310 GO:0042802 GO:0045087 GO:0050750 GO:0050830
GL_000794	N-acetylgalactosaminyltransferase 7	Q86SF2	Homo sapiens	9606	Golgi apparatus Golgi membrane O-glycan processing carbohydrate binding carbohydrate metabolic process extracellular exosome membrane metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0005975 GO:0006493 GO:0016020 GO:0016266 GO:0030246 GO:0046872 GO:0070062
GL_000077	B-cell differentiation antigen CD72	P21854	Homo sapiens	9606	carbohydrate binding cell adhesion plasma membrane signaling receptor binding transmembrane signaling receptor activity	GO:0004888 GO:0005102 GO:0005886 GO:0007155 GO:0030246