GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID	GO Labels ▲	GO IDs
GL_002315	Hemagglutinin (Fragment)	P03462	Influenza B virus (B/Hong Kong/8/1973)	427826	endocytosis involved in viral entry into host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell plasma membrane host cell surface receptor binding membrane viral envelope virion attachment to host cell virion membrane	GO:0016020 GO:0019031 GO:0019062 GO:0019064 GO:0020002 GO:0039654 GO:0046789 GO:0055036 GO:0075509
GL_002191	Spike glycoprotein (Fragment)	Q1HLC5	Bovine coronavirus	11128	endocytosis involved in viral entry into host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell plasma membrane membrane receptor-mediated virion attachment to host cell viral envelope virion membrane	GO:0016020 GO:0019031 GO:0019064 GO:0020002 GO:0039654 GO:0046813 GO:0055036 GO:0075509
GL_002020	Hepatic lectin	P02707	Gallus gallus	9031	endocytosis external side of plasma membrane fucose binding mannose binding	GO:0005537 GO:0006897 GO:0009897 GO:0042806
GL_002337	Spike glycoprotein	P0DTC2	Severe acute respiratory syndrome coronavirus 2	2697049	entry receptor-mediated virion attachment to host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endoplasmic reticulum-Golgi intermediate compartment membrane host cell plasma membrane host cell surface host cell surface receptor binding host extracellular space identical protein binding membrane fusion plasma membrane positive regulation of viral entry into host cell receptor ligand activity receptor-mediated endocytosis of virus by host cell receptor-mediated virion attachment to host cell structural constituent of virion suppression by virus of host tetherin activity suppression by virus of host type I interferon-mediated signaling pathway viral envelope viral translation virion attachment to host cell virion membrane	GO:0005886 GO:0019031 GO:0019062 GO:0019064 GO:0019065 GO:0019081 GO:0020002 GO:0039502 GO:0039587 GO:0039654 GO:0039660 GO:0042802 GO:0043655 GO:0044173 GO:0044228 GO:0046598 GO:0046789 GO:0046813 GO:0048018 GO:0055036 GO:0061025 GO:0098670
GL_002006	E-selectin	P98110	Sus scrofa	9823	external side of plasma membrane extracellular space heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte tethering or rolling metal ion binding oligosaccharide binding positive regulation of leukocyte tethering or rolling response to cytokine sialic acid binding	GO:0005615 GO:0007157 GO:0009897 GO:0033691 GO:0034097 GO:0046872 GO:0050901 GO:0070492 GO:1903238
GL_002386	Trefoil factor 3	Q07654	Homo sapiens	9606	extracellular region extracellular space identical protein binding maintenance of gastrointestinal epithelium regulation of glucose metabolic process secretory granule	GO:0005576 GO:0005615 GO:0010906 GO:0030141 GO:0030277 GO:0042802
GL_002335	Botulinum neurotoxin type A	P0DPI0	Clostridium botulinum	1491	extracellular region ganglioside GT1b binding host cell cytoplasmic vesicle host cell cytosol host cell plasma membrane host cell presynaptic membrane membrane metalloendopeptidase activity protein transmembrane transporter activity proteolysis toxin activity zinc ion binding	GO:0004222 GO:0005576 GO:0006508 GO:0008270 GO:0008320 GO:0016020 GO:0020002 GO:0044161 GO:0044164 GO:0044231 GO:0090729 GO:1905576
GL_002353	Botulinum neurotoxin type D	P19321	Clostridium botulinum D phage	29342	extracellular region ganglioside GT1b binding metalloendopeptidase activity protein transmembrane transporter activity proteolysis toxin activity zinc ion binding	GO:0004222 GO:0005576 GO:0006508 GO:0008270 GO:0008320 GO:0090729 GO:1905576
GL_002352	Botulinum neurotoxin type C	P18640	Clostridium phage c-st	12336	extracellular region ganglioside binding membrane protein proteolysis metalloendopeptidase activity negative regulation by symbiont of host neurotransmitter secretion negative regulation of calcium ion-dependent exocytosis protein transmembrane transporter activity toxin activity zinc ion binding	GO:0004222 GO:0005576 GO:0008270 GO:0008320 GO:0033619 GO:0035594 GO:0044762 GO:0045955 GO:0090729
GL_002374	Shiga-like toxin 1 subunit B	P69179	Enterobacteria phage H-19B	69932	extracellular region hemolysis by symbiont of host erythrocytes modulation of host virulence by virus toxin activity	GO:0005576 GO:0019836 GO:0090729 GO:0098676