GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID	GO Labels	GO IDs
GL_000165	C-type lectin domain family 2 member I	Q9WVF9	Mus musculus	10090	T cell receptor signaling pathway carbohydrate binding cell surface endoplasmic reticulum external side of plasma membrane membrane raft assembly natural killer cell lectin-like receptor binding negative regulation of osteoclast differentiation positive regulation of immunological synapse formation receptor clustering regulation of T cell proliferation regulation of actin filament polymerization regulation of interleukin-2 production transmembrane signaling receptor activity	GO:0001765 GO:0004888 GO:0005783 GO:0009897 GO:0009986 GO:0030246 GO:0030833 GO:0032663 GO:0042129 GO:0043113 GO:0045671 GO:0046703 GO:0050852 GO:2000522
GL_000703	Lectin 1	Q7M3Y0	Apostichopus japonicus	307972	carbohydrate binding	GO:0030246
GL_000384	Ficolin-1	O00602	Homo sapiens	9606	G protein-coupled receptor binding G protein-coupled receptor signaling pathway antigen binding carbohydrate binding carbohydrate derivative binding cell surface pattern recognition receptor signaling pathway collagen trimer collagen-containing extracellular matrix complement activation, lectin pathway external side of plasma membrane extracellular region extracellular space ficolin-1-rich granule lumen metal ion binding negative regulation of viral entry into host cell pattern recognition receptor activity plasma membrane positive regulation of interleukin-8 production positive regulation of opsonization protein localization to cell surface proteolysis recognition of apoptotic cell secretory granule lumen serine-type endopeptidase complex sialic acid binding signaling receptor binding	GO:0001664 GO:0001867 GO:0002752 GO:0003823 GO:0005102 GO:0005576 GO:0005581 GO:0005615 GO:0005886 GO:0006508 GO:0007186 GO:0009897 GO:0030246 GO:0032757 GO:0033691 GO:0034394 GO:0034774 GO:0038187 GO:0043654 GO:0046597 GO:0046872 GO:0062023 GO:0097367 GO:1903028 GO:1904813 GO:1905370
GL_000757	Lectin-like protein LEC	Q9LJR2	Arabidopsis thaliana	3702	apoplast carbohydrate binding cellular response to chitin cellular response to ethylene stimulus cellular response to jasmonic acid stimulus cytosol defense response to fungus ethylene-activated signaling pathway response to wounding	GO:0005829 GO:0009611 GO:0009873 GO:0030246 GO:0048046 GO:0050832 GO:0071323 GO:0071369 GO:0071395
GL_000665	Ladderlectin	P81018	Oncorhynchus mykiss	8022	brush border carbohydrate binding chitin binding cytolytic granule cytoplasm cytosol extracellular space plasma membrane	GO:0005615 GO:0005737 GO:0005829 GO:0005886 GO:0005903 GO:0008061 GO:0030246 GO:0044194
GL_001693	Lysosomal alpha-glucosidase	Q5R7A9	Pongo abelii	9601	alpha-1,4-glucosidase activity carbohydrate binding glycogen catabolic process lysosomal membrane maltose alpha-glucosidase activity	GO:0004558 GO:0005765 GO:0005980 GO:0030246 GO:0032450
GL_000790	N-acetyl-D-galactosamine-binding lectin subunit A (Fragment)	P36230	Iris x hollandica	35876	carbohydrate binding negative regulation of translation rRNA N-glycosylase activity toxin activity	GO:0017148 GO:0030246 GO:0030598 GO:0090729
GL_000432	G-type lectin S-receptor-like serine/threonine-protein kinase At4g03230	Q9ZR08	Arabidopsis thaliana	3702	ATP binding calmodulin binding carbohydrate binding phosphorylation plasma membrane protein serine kinase activity protein serine/threonine kinase activity recognition of pollen ubiquitin protein ligase binding	GO:0004674 GO:0005516 GO:0005524 GO:0005886 GO:0016310 GO:0030246 GO:0031625 GO:0048544 GO:0106310
GL_001463	ER degradation-enhancing alpha-mannosidase-like protein 1	P38888	Saccharomyces cerevisiae S288C	559292	calcium ion binding carbohydrate binding carbohydrate metabolic process endoplasmic reticulum endoplasmic reticulum lumen endoplasmic reticulum mannose trimming endoplasmic reticulum quality control compartment mannose trimming involved in glycoprotein ERAD pathway mannosyl-oligosaccharide 1,2-alpha-mannosidase activity mannosyl-oligosaccharide 1,2-alpha-mannosidase complex membrane positive regulation of endoplasmic reticulum unfolded protein response protein alpha-1,2-demannosylation protein glycosylation response to unfolded protein ubiquitin-dependent glycoprotein ERAD pathway	GO:0004571 GO:0005509 GO:0005783 GO:0005788 GO:0005975 GO:0006486 GO:0006986 GO:0016020 GO:0030246 GO:0036508 GO:0044322 GO:0097466 GO:0106055 GO:1900103 GO:1904380 GO:1904382
GL_002300	Enterotoxin type B	P01552	Staphylococcus aureus	1280	extracellular region metal ion binding toxin activity	GO:0005576 GO:0046872 GO:0090729